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J Clin Neurol.  2008 Mar;4(1):51-57. 10.3988/jcn.2008.4.1.51.

Multiple Sclerosis and Peripheral Multifocal Demyelinating Neuropathies Occurring in a Same Patient

Affiliations
  • 1Department of Neurology, College of Medicine, Ewha Womans University Medical Center, Seoul, Korea. pkd1165@ewha.ac.kr

Abstract

The co-occurrence of multiple sclerosis and peripheral demyelinating neuropathy is rare. It has been disputed whether these are pathologically related or coincidental findings. We report a 36-year-old woman who presented with diplopia, right facial palsy and left-sided weakness. Brain magnetic resonance imaging showed a lesion indicative of central demyelinating disease. Nerve conduction studies revealed peripheral multifocal demyelinating neuropathies. We suggest that the central and the peripheral lesions may be continua of a demyelinating process.

Keyword

Multiple sclerosis; Demyelinating neuropathy; Conduction block

MeSH Terms

Adult
Brain
Demyelinating Diseases
Diplopia
Facial Paralysis
Female
Humans
Magnetic Resonance Imaging
Multiple Sclerosis
Neural Conduction
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