- Nusinersen as a Therapeutic Agent for Spinal Muscular Atrophy
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Li Q
- KMID: 2471912
- Yonsei Med J.
- 2020 Apr;61(4):273-283.
- doi: 10.3349/ymj.2020.61.4.273
The reduction of survival motor neuron (SMN) protein causes spinal muscular atrophy (SMA), an autosomal recessive neuromuscular disease. Nusinersen is an antisense oligonucleotide, approved by the FDA, which specifically binds... -
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- Reflex and Spontaneous Movements in Adult Patients during the Process of Determining Brain Death in Korea
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Kim DH, Kwon OY, Yang TW, Kim M, Lee J, Cho W, Yeom JS, Kim YS
- KMID: 2471792
- J Korean Med Sci.
- 2020 Mar;35(11):e71.
- doi: 10.3346/jkms.2020.35.e71
BACKGROUND: Brain death is a clinical diagnosis that implies irreversible loss of function of the entire brain, including the brainstem and both hemispheres. Based on previous reports, it is not... -
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- Acute Leukemia Relapse Presenting as Recurrent Involvement of the Optic Nerve
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Lee SY, Yoon JH, Chung SA
- KMID: 2471776
- J Korean Ophthalmol Soc.
- 2020 Mar;61(3):319-324.
- doi: 10.3341/jkos.2020.61.3.319
PURPOSE: To report two cases with recurrent involvement of the optic nerve as the initial sign of acute leukemic relapse. CASE SUMMARY: An 8-year-old male with acute lymphoblastic leukemia on the... -
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- Changes in attention variables in those who treated with anticholinergic agents for nonmonosymptomatic enuresis
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Jang G, Im YJ, Suh J, Park K
- KMID: 2471077
- Investig Clin Urol.
- 2020 Mar;61(2):207-215.
- doi: 10.4111/icu.2020.61.2.207
PURPOSE: Brain dysfunction related to areas regarding attention and arousal may occur not only in patients with attention-deficit/hyperactivity disorder (ADHD) but also in patients with enuresis and daytime symptoms. This... -
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- Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats
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Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK
- KMID: 2471038
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):165-171.
- doi: 10.4196/kjpp.2020.24.2.165
Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma... -
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- Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders
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Choi S, Kim SW, Jeon HR, Lee JS, Kim DY, Lee JW
- KMID: 2469628
- Brain Neurorehabil.
- 2020 Mar;13(1):e6.
- doi: 10.12786/bn.2020.13.e6
Robots are being used to assist the recovery of walking ability for patients with neurologic disorders. This study aimed to evaluate the feasibility and functional improvement of training with robot-assisted... -
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- Ultrasonographic Demonstration of the Tissue Microvasculature in Children: Microvascular Ultrasonography Versus Conventional Color Doppler Ultrasonography
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Yoo J, Je BK, Choo JY
- KMID: 2471632
- Korean J Radiol.
- 2020 Feb;21(2):146-158.
- doi: 10.3348/kjr.2019.0500
Microvascular ultrasonographic imaging is the most recent and unique Doppler ultrasound technique. It uses an advanced clutter filter that can remove clutter artifacts and preserve the low-velocity microvascular flow signal.... -
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- Clinical Application of Meditation in Children and Adolescents
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Kwack YS, Moon DS
- KMID: 2471264
- J Korean Neuropsychiatr Assoc.
- 2020 Feb;59(1):36-43.
- doi: 10.4306/jknpa.2020.59.1.36
Meditation is one of the psychological therapeutic techniques that can be applied to many conditions, including stress reduction. Meditation can be an alternative to overcoming the limitations of existing therapies,... -
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- Opioids and Antidepressants for Pain Control in Musculoskeletal Disease
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Park SJ, Kim WS, Jang T
- KMID: 2470764
- J Korean Orthop Assoc.
- 2020 Feb;55(1):1-8.
- doi: 10.4055/jkoa.2020.55.1.1
The progression of aging and the increase in musculoskeletal diseases have led to an increase in invasive treatment methods, including various surgical methods, but conservative treatment should be attempted before... -
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- Evolution of tobacco products
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Lee S, Kim J
- KMID: 2470063
- J Korean Med Assoc.
- 2020 Feb;63(2):88-95.
- doi: 10.5124/jkma.2020.63.2.88
Tobacco products are rapidly evolving. Since the World Health Organization Framework Convention on Tobacco Control came to effect in 2005, the parties of the treaty have been aiming to control... -
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- Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report
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Kim JH, Park NH, Park JY, Kim SJ
- KMID: 2469201
- J Korean Soc Radiol.
- 2020 Jan;81(1):243-247.
- doi: 10.3348/jksr.2020.81.1.243
We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst.... -
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- Sevoflurane with opioid or dexmedetomidine infusions in dogs undergoing intracranial surgery: a retrospective observational study
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Marquez-Grados F, Vettorato , Corletto F
- KMID: 2469023
- J Vet Sci.
- 2020 Jan;21(1):e8.
- doi: 10.4142/jvs.2020.21.e8
This study reports the clinical use of two sevoflurane-based anesthetic techniques in dogs undergoing craniectomy. Twenty-one animals undergoing elective rostrotentorial or transfrontal craniectomy for brain tumor excision, anesthetized with sevoflurane,... -
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- Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells
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Hwang S, Kim JK
- KMID: 2468142
- Chonnam Med J.
- 2020 Jan;56(1):20-26.
- doi: 10.4068/cmj.2020.56.1.20
We examined the effect of fluoxetine, a selective serotonin reuptake inhibitor antidepressant, on neuronal viability in mouse cortical near-pure neuronal cultures. Addition of fluoxetine to the media for 24 hours... -
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- “Self-Neuroenhancementâ€: The Last Frontier of Noninvasive Brain Stimulation?
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Fisicaro F, Lanza G, Bella R, Pennisi M
- KMID: 2467800
- J Clin Neurol.
- 2020 Jan;16(1):158-159.
- doi: 10.3988/jcn.2020.16.1.158
No abstract available. -
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- Clinical Usefulness of ¹â¸F-FC119S Positron-Emission Tomography as an Auxiliary Diagnostic Method for Dementia: An Open-Label, Single-Dose, Evaluator-Blind Clinical Trial
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Lee I, Na HR, Byun BH, Lim I, Kim BI, Choi CW, Ko IO, Lee KC, Kim KM, Park SY, Kim YK, Lee JY, Bu SH, Kim JH, Kil HS, Park C, Chi DY, Ha JH, Lim SM
- KMID: 2467795
- J Clin Neurol.
- 2020 Jan;16(1):131-139.
- doi: 10.3988/jcn.2020.16.1.131
BACKGROUND AND PURPOSE: The aim of this study was to determine the diagnostic performance and safety of a new ¹â¸F-labeled amyloid tracer, ¹â¸F-FC119S. METHODS: This study prospectively recruited 105 participants, comprising... -
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- Individual-Level Lesion-Network Mapping to Visualize the Effects of a Stroke Lesion on the Brain Network: Connectograms in Stroke Syndromes
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Lim JS, Lee JJ, Woo CW, Song J, Oh MS, Yu KH, Lee BC
- KMID: 2467793
- J Clin Neurol.
- 2020 Jan;16(1):116-123.
- doi: 10.3988/jcn.2020.16.1.116
BACKGROUND AND PURPOSE: Similar-sized stroke lesions at similar locations can have different prognoses in clinical practice. Lesion-network mapping elucidates network-level effects of lesions that cause specific neurologic symptoms and signs,... -
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- Coexistence of Cerebral Microbleeds and Amyloid Pathology in Patients with Cognitive Complaints
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Lim EY, Ryu SY, Shim YS, Yang DW, Cho AH
- KMID: 2467788
- J Clin Neurol.
- 2020 Jan;16(1):83-89.
- doi: 10.3988/jcn.2020.16.1.83
BACKGROUND AND PURPOSE: We investigated the prevalence of amyloid positivity and cerebral microbleeds (CMBs) in subjects with cognitive complaints with the aim of identifying differences in clinical parameters and cognitive... -
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- A Cortical Substrate for Square-Wave Jerks in Progressive Supranuclear Palsy
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Anagnostou E, Karavasilis E, Potiri I, Constantinides V, Efstathopoulos E, Kapaki E, Potagas C
- KMID: 2467782
- J Clin Neurol.
- 2020 Jan;16(1):37-45.
- doi: 10.3988/jcn.2020.16.1.37
BACKGROUND AND PURPOSE: Square-wave jerks (SWJs) are the most common saccadic intrusion in progressive supranuclear palsy (PSP), but their genesis is uncertain. We aimed to determine the characteristics of SWJs... -
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- Plasma Fibroblast Growth Factor 23 Concentration Is Associated with Intracranial Cerebral Atherosclerosis in Acute Ischemic Stroke Patients
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Chang Y, Kim J, Woo HG, Ryu DR, Oh HJ, Song TJ
- KMID: 2467781
- J Clin Neurol.
- 2020 Jan;16(1):29-36.
- doi: 10.3988/jcn.2020.16.1.29
BACKGROUND AND PURPOSE: Fibroblast growth factor 23 (FGF23) is associated with atherosclerosis via nitric-oxide-associated endothelial dysfunction and calcium-phosphate-related bone mineralization. This study aimed to determine the association of the plasma... -
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- Decreased inward rectifier and voltage-gated K⺠currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats
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Kim SE, Yin MZ, Kim HJ, Vorn R, Yoo HY, Kim SJ
- KMID: 2466575
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):111-119.
- doi: 10.4196/kjpp.2020.24.1.111
In vascular smooth muscle, K⺠channels, such as voltage-gated K⺠channels (Kv), inward-rectifier K⺠channels (Kir), and big-conductance Ca²âº-activated K⺠channels (BK(Ca)), establish a hyperpolarized membrane potential and counterbalance the... -
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