Korean J Nephrol.
2002 Jul;21(4):680-685.
A Case of Penicillium merneffei CAPD Peritonitis
- Affiliations
-
- 1Department of Internal Medicine, Collage of Medicine, Yonsei University, Seoul, Korea. khchoi6@yumc.yonsei.ac.kr
- 2Department of Clinical Pathology, Collage of Medicine, Yonsei University, Seoul, Korea.
- 3Department of Clinical Pathology, Collage of Medicine, Chonnam University, Kwangju, Korea.
Abstract
- P. marneffei is a fungus that causes life-threatening disseminated infection in a geographically distinct areas of the world. Following the first case of human infection in 1959, the incidence of this infection has risen markedly during the past 5 years. However, even in the midst of such rapid increase, the infection has always occurred only in a limited geographic distributions or in persons who have visited this limited geographic areas. These areas include Myanmar, Hong Kong, Indonesia, Laos, Malaysia, Singapore, Taiwan, Thailand, Vietnam, and the Guangxi province of southern China. P. marneffei infection occurs mostly in immunocompromised patients, particularly AIDS patients. P. marneffei infection commonly presents with skin and subcutanous tissue infection, fungemia, diarrhea, bone marrow infection, and generalized lymphadenopathy with hepatosplenomegaly. We report the case of continuous ambulatory peritoneal dialysis-associated peritonitis caused by P. marneffei. The case occurred in Korea, a non-endemic area of P. marneffei, in a non-AIDS patient who has not been exposed to any of the endemic areas. This warrants further consideration in determining the yet unknown transmission route of this fungal organism. P. marneffei was diagnosed without delay by 18sRNA PCR and sequencing, and was later confirmed by culture. PCR and sequencing may contribute to the early diagnosis of the P. marneffei infection, which is important given this infection's ability to progress to a systemic infection with high mortality rate when diagnosis and management are delayed.
MeSH Terms
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Vancomycin-Resistant Enterococci P eritonitis in a Pediatric P atient on CAPD Successfully Treated with Linezolid
- A Case of Trichosporon beigelii Peritonitis in CAPD
- A Case of Trichosoporon insectorum Peritonitis in a Continous Ambulatory Peritoneal Dialysis Patient
- A Case of Vancomycin Resistant Enterococci(VRE) Peritonitis in a Patient on CAPD
- A Case of Pancreatitis during CAPD
