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Genomic and Transcriptomic Characterization of Gastric Cancer with Bone Metastasis

Oh S, Nam SK, Lee KW, Lee HS, Park Y, Kwak Y, Lee KS, Kim JW, Kim JW, Kang M, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH

Purpose Bone metastasis (BM) adversely affects the prognosis of gastric cancer (GC). We investigated molecular features and immune microenvironment that characterize GC with BM compared to GC without BM. Materials and...
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A Phase II Trial of Nintedanib in Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma: In-Depth Analysis of Nintedanib Arm from the KCSG HN 15-16 TRIUMPH Trial

Kim KH, Lim SM, Ahn HK, Lee YG, Lee KW, Ahn MJ, Keam B, Kim HR, Lee HW, An HJ, Kim JS

Purpose Precision oncology approach for recurrent and metastatic head and neck squamous cell carcinoma (HNSCC) is necessary due to its dismal prognosis. We performed a genomic profile-based umbrella trial of...
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Hirayama Disease with Isolated Spinal Cord Atrophy

Lee Kw, Kim T, Kim SH, Hong YJ, An JY

This report presents a young-aged man with Hirayama disease who had muscle atrophy and weakness strictly confined to the C8/T1 myotome that consistently accorded with electromyographic results. In the magnetic...
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Latanoprostene Bunod 0.024% w/v Treatment of Open-anlge Glaucoma: Short-term Effects, Safety, and Changes in Ocular Blood

Kim HW, Lee CE, Seo S, Lee KW, Lee CH

Purpose: To study the short-term intraocular pressure (IOP)-lowering effect and optic nerve head (ONH) blood flow improvement after switching from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v. Methods: This prospective...
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A Phase 3 Randomized Clinical Trial to Compare Efficacy and Safety between Combination Therapy and Monotherapy in Elderly Patients with Advanced Gastric Cancer (KCSG ST13-10)

Lee KW, Zang DY, Ryu MH, Han HS, Kim KH, Kim MJ, Koh SA, Lee SS, Koo DH, Ko YH, Sohn BS, Kim JW, Park JH, Nam BH, Choi IS

Purpose This study evaluated whether combination therapy is more effective than monotherapy in elderly patients with metastatic or recurrent gastric cancer (MRGC) as first-line chemotherapy. Materials and Methods Elderly (≥ 70...
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Intramuscular Neural Distribution of Adductor Pollicis Muscle Spasticity in Cadaver Model Regarding Botulinum Neurotoxin Treatment

Yi KH, Lee KW, Hwang Y, An MH, Ahn HS, Hu H, Lee JH, Lee HJ

Purpose: The adductor pollicis muscle is frequently targeted for botulinum neurotoxin injective treatment for spasticity. However, there are no injective guidelines for delivering injection to the muscle. Materials and Methods: A...
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150 Years of Medical History Education in Japan: History and Challenges

LEE KW

This paper is the first attempt to get a broad view of the history of modern medical history education in Japan, from the origin of medical history education in the...
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Recurrence in patients with totally necrotic nodules of hepatocellular carcinoma after liver transplantation: “totally” an inaccurate description

Kim J, Hong SK, Kim JY, Lee J, Choi HH, Lee S, Hong Sy, Lee JM, Choi Y, Yi NJ, Lee KW, Suh KS

Purpose: Total necrosis of hepatocellular carcinoma (HCC) achieved via locoregional treatment (LRT) is considered to indicate a lack of tumor viability. Nonetheless, there is insufficient evidence of recurrence after liver...
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Modified Charlson comorbidity index as a survival prediction tool for older patients after liver transplantation

Choi J, Choi EW, Choi Y, Hong Sy, Suh S, Hong K, Han ES, Lee Jm, Hong SK, Yi NJ, Lee KW, Suh KS

Purpose: An increasing number of older patients now undergo liver transplantation (LT). Although the overall outcomes in older patients are not different from those of younger patients, there is no...
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Rehabilitation with minimal increase in occlusal vertical dimension in a patient with excessive tooth wear and edge-to-edge bite

Kim HY, Kim SA, Lee YS, Lee KW, Bang JH

Although tooth wear is a normal process due to aging, severe tooth wear causes various complications such as increased tooth sensitivity, loss of tooth structure, and pulp complications. In the...
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Zirconia resin-bonded fixed partial denture in maxillary single-tooth edentulous area: A case report

Oh R, Jang HW, Kim NH, Bang JH, Lee KW, Lee YS

Resin-bonded fixed partial denture (RBFPD)as known as Maryland bridge is is a well-known conservative method for its minimized invasion of the teeth for an anterior single tooth edentulous area. Despite...
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Long-term outcomes of liver transplantation using grafts from donors with active hepatitis B virus replication: a multicenter cohort study

Gang S, Choi Y, Lee 2 B, Yoon KC, Hong Sy, Suh S, Han ES, Hong SK, Lee HW, Cho JY, Yi Nj, Lee KW, Suh KS

Purpose: Liver grafts from donors with HBV infection contributed to expanding the donor pool under the hepatitis B immunoglobulin and antiviral agents (nucleos(t)ide analogues) in the HBV-endemic area. We report...
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Impact of preoperative ultrasonography for predicting the prognosis of deceased donor kidney transplantation

Yun SO, Lee KW, Park JB, Kim MJ, Park SY, Park B

Purpose: This study evaluated the role of donor kidney ultrasonography (US) for predicting functional kidney volume and identifying ideal kidney grafts in deceased donor kidney transplantation. Methods: In total, 272 patients...
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Posttransplant sequential adrenal and spine metastasis of hepatocellular carcinoma responsive to combined regorafenib and radiotherapy: a case report

Kim JY, Yi NJ, Kim YJ, Chie EK, Kim J, Choi HH, Lee J, Lee S, Hong SY, Lee JM, Hong SK, Choi Y, Lee KW, Suh KS

Adrenal and spinal metastases of hepatocellular carcinoma (HCC) are rare entities with significant morbidity and mortality, particularly after liver transplantation (LT). We report a case of a 49-year-old man who...
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Microbiome in urological diseases: Axis crosstalk and bladder disorders

Choi HW, Lee KW, Kim YH

Since the identification of the human urinary microbiome, numerous studies have characterized this microbial community and improved our knowledge of its association with urinary diseases. This association between urinary diseases...
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Evaluating the Safety and effectivenesS in adult KorEaN patients treated with Tolvaptan for management of autosomal domInAnt poLycystic kidney disease (ESSENTIAL): short-term outcomes during the titration period

Huh H, Kim YS, Chung W, Kim YL, Kim Y, Han S, Jung Y, Na KY, Lee KB, Oh YK, Park HC, Han SH, Yoo TH, Kim YH, Kim SW, Lee KW, Park HC, Kim SG, Kim H, Lee CH, Bae KT, Oh KH, Ahn C, Ryu HJ, Kim YC

Background: Tolvaptan reduces height-adjusted total kidney volume (htTKV) and renal function decline in autosomal dominant polycystic kidney disease (ADPKD). This study was aimed at investigating the efficacy and safety of...
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Impact of Body Mass Index on Survival Depending on Sex in 14,688 Patients with Gastric Cancer in a Tertiary Hospital in South Korea

Jo HH, Kim N, Jang J, Choi Y, Park J, Park YM, Ahn S, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH

Background/Aims: The incidence and prognosis of gastric cancer (GC) shows sex difference. This study aimed to evaluate the effect of body mass index (BMI) on GC survival depending on sex. Methods: The...
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Impact of Post-Transplant Diabetes Mellitus on Survival and Cardiovascular Events in Kidney Transplant Recipients

Jeon JY, Han-Bit S, Park BH, Lee N, Kim HJ, Kim DJ, Lee KW, Han SJ

Background: Post-transplant diabetes mellitus (PTDM) is a risk factor for poor outcomes after kidney transplantation (KT). However, the outcomes of KT have improved recently. Therefore, we investigated whether PTDM is...
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The Clinical Course and Prognosis of Patients With Nontuberculous Mycobacterial Pulmonary Disease After Solid Organ Transplantation

Kim JY, Han A, Lee H, Ha J, Lee KW, Suh KS, Yi NJ, Min S, Hong SK, Kim YC, Choi Y, Yim JJ, Kwak N

Background: Due to impaired cell-mediated immunity, solid organ transplantation (SOT) recipients are at increased risk of developing nontuberculous mycobacterial pulmonary disease (NTM-PD). However, the clinical course of NTM-PD in SOT...
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Complete denture rehabilitation of partially glossectomized patient using palatal augmentation prosthesis: A case report

Lee HK, Kim NH, Jang HW, Yim SY, Lee KW, Kim SY

The tongue is one of the most common sites of oral cancer. Glossectomy is known as the gold standard for tongue cancer treatment. However, surgical removal can lead to reduced...
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