- Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
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Lin CH, Hsieh YS, Sun YC, Huang WH, Chen SL, Weng ZK, Lin TH, Wu YR, Chang KH, Huang HJ, Lee GC, Hsieh-Li HM, Lee-Chen GJ
- KMID: 2537589
- Biomol Ther.
- 2023 Jan;31(1):127-138.
- doi: 10.4062/biomolther.2022.035
Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer’s disease (AD). In this study, structure-based virtual... -
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- Benefit of Using Early ContrastEnhanced 2D T2-Weighted Fluid-Attenuated Inversion Recovery Image to Detect Leptomeningeal Metastasis in Lung-Cancer Staging
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Kim HJ, Lee J, Lee AL, Lee JW, Kim CK, Kim JY, Park ST, Chang KH
- KMID: 2533869
- Investig Magn Reson Imaging.
- 2022 Mar;26(1):32-42.
- doi: 10.13104/imri.2022.26.1.32
Purpose: To evaluate the clinical benefit of 2D contrast-enhanced T2 fluidattenuated inversion recovery (CE-T2 FLAIR) image for detecting leptomeningeal metastasis (LM) in the brain metastasis work-up for lung cancer. Materials and... -
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- Detector-based Dose Verification System for Phantom-less Delivery Quality Assurance in Tomothearpy
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Han MC, Han MC, Chang KH, Chang KH, Kim J, Kim J, Han SC, Han SC, Park K, Park K, Kim DW, Kim DW, Kim HJ, Kim HJ, Kim JS, Kim JS
- KMID: 2510030
- Prog Med Phys.
- 2020 Sep;31(S1):S5.
Purpose: We developed a new technique, named TomoCHECK, to perform phantom-less delivery quality assurance (DQA) system in Tomothearpy using an exit detector and software-based QA platform. Methods: TomoCHECK was designed to... -
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- Medical students' satisfaction with clinical clerkship and its relationship with professional self-concept
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Yu JH, Lee SK, Kim M, Chae SJ, Lim KY, Chang KH
- KMID: 2452113
- Korean J Med Educ.
- 2019 Jun;31(2):125-133.
- doi: 10.3946/kjme.2019.124
PURPOSE: Medical students construct their identity as a student physician through clinical clerkship. However, there is a lack of research on the effect of clinical clerkship on professional self-concept formation.... -
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- History-indicated cerclage: the association between previous preterm history and cerclage outcome
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Lee KN, Whang EJ, Chang KH, Song JE, Son GH, Lee KY
- KMID: 2420148
- Obstet Gynecol Sci.
- 2018 Jan;61(1):23-29.
- doi: 10.5468/ogs.2018.61.1.23
OBJECTIVE: Our hospital's policy is to perform history-indicated cerclage (HIC) for pregnant patients with 1 or more second-trimester pregnancy losses. Recently, the American College of Obstetricians and Gynecologists (ACOG) guideline... -
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- Potential bias factors that affect the course evaluation of students in preclinical courses
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Chae SJ, Kim M, Chang KH, Chung YS
- KMID: 2413863
- Korean J Med Educ.
- 2017 Jun;29(2):73-80.
- doi: 10.3946/kjme.2017.54
PURPOSE: We aim to identify what potential bias factors affected students' overall course evaluation, and to observe what factors should be considered in the curriculum evaluation system of medical schools. METHODS:... -
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- Attitudes Regarding HPV Vaccinations of Children among Mothers with Adolescent Daughters in Korea
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Lee KN, Chang KH, Cho SS, Park SH, Park ST
- KMID: 2417595
- J Korean Med Sci.
- 2017 Jan;32(1):130-134.
- doi: 10.3346/jkms.2017.32.1.130
The aim of this study, carried out before the beginning of human papillomavirus (HPV) vaccinations as a National Immunization Program (NIP) in Korea in 2016, is to assess the ranges... -
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- Clinical outcomes and neurodevelopmental outcome of prenatally diagnosed agenesis of corpus callosum in single center of Korea
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Kim SE, Jang HI, Chang KH, Sung JH, Lee J, Lee J, Choi SJ, Oh SY, Roh CR, Kim JH
- KMID: 2383202
- Obstet Gynecol Sci.
- 2017 Jan;60(1):8-17.
- doi: 10.5468/ogs.2017.60.1.8
OBJECTIVE: With recent advances and frequent use of prenatal ultrasound, the antenatal diagnosis of agenesis of the corpus callosum (ACC) is not rare in obstetrics practices. However, information regarding the... -
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- Clinical Implications of High Definition Multileaf Collimator (HDMLC) Dosimetric Leaf Gap (DLG) Variations
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Chang KH, Ji Y, Kwak J, Kim SW, Jeong C, Cho B, Park JH, Yoon SM, Ahn SD, Lee SW
- KMID: 2376540
- Prog Med Phys.
- 2016 Sep;27(3):111-116.
- doi: 10.14316/pmp.2016.27.3.111
This study is to evaluate the dosimetric impact of dosimetric leaf gap (DLG) and transmission factor (TF) at different measurement depths and field sizes for high definition multileaf collimator (HD... -
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- Can disclosure of scoring rubric for basic clinical skills improve objective structured clinical examination?
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Chae SJ, Kim M, Chang KH
- KMID: 2417519
- Korean J Med Educ.
- 2016 Jun;28(2):179-183.
- doi: 10.3946/kjme.2016.28
PURPOSE: To determine whether disclosure of scoring rubric for objective basic clinical skills can improve the scores on the objective structured clinical examination (OSCE) in medical students. METHODS: Clinical performance score... -
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- Use of Polymyxin B Hemoperfusion in a Patient with Septic Shock and Septic Cardiomyopathy Who Was Placed on Extracorporeal Membrane Oxygen Support
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Shin SH, Lee H, Choi AJ, Chang KH, Suh GY, Chung CR
- KMID: 2350919
- Korean J Crit Care Med.
- 2016 May;31(2):123-128.
- doi: 10.4266/kjccm.2016.31.2.123
Although shock in sepsis is usually managed successfully by conventional medical treatment, a subset of cases do not respond and may require salvage therapies such as veno-arterial extracorporeal membrane oxygenation... -
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- The relationship among self-efficacy, perfectionism and academic burnout in medical school students
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Yu JH, Chae SJ, Chang KH
- KMID: 2374226
- Korean J Med Educ.
- 2016 Mar;28(1):49-55.
- doi: 10.3946/kjme.2016.9
PURPOSE: The purpose of this study was to examine the relationship among academic self-efficacy, socially-prescribed perfectionism, and academic burnout in medical school students and to determine whether academic self-efficacy had... -
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- Longitudinal analysis of the effect of academic failure tolerance on academic achievement fluctuation in medical school students
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Chae SJ, Kim M, Chang KH
- KMID: 2374223
- Korean J Med Educ.
- 2016 Mar;28(1):25-28.
- doi: 10.3946/kjme.2016.6
PURPOSE: Academic failure tolerance (AFT) is one of the important psychological concepts in education, but its applications in medical education are rare. Thus, the purpose of this study was to... -
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- Gestational age at delivery and neonatal outcome in uncomplicated twin pregnancies: what is the optimal gestational age for delivery according to chorionicity?
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Lee HJ, Kim SH, Chang KH, Sung JH, Choi SJ, Oh SY, Roh CR, Kim JH
- KMID: 2152638
- Obstet Gynecol Sci.
- 2016 Jan;59(1):9-16.
- doi: 10.5468/ogs.2016.59.1.9
OBJECTIVE: To investigate the neonatal outcome according to the gestational age at delivery and to determine the optimal timing for delivery in uncomplicated monochorionic and dichorionic twin pregnancies. METHODS: This is... -
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- Clinical characteristics and outcome of cancer diagnosed during pregnancy
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Shim MH, Mok CW, Chang KH, Sung JH, Choi SJ, Oh SY, Roh CR, Kim JH
- KMID: 2152637
- Obstet Gynecol Sci.
- 2016 Jan;59(1):1-8.
- doi: 10.5468/ogs.2016.59.1.1
OBJECTIVE: The aim of this study is to describe the clinical characteristics and outcome of cancer diagnosed during pregnancy. METHODS: This is a retrospective cohort study of women who were diagnosed... -
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- Cerebellar Clear Cell Ependymoma in a 10-Year-Old Girl
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Thinzar AN, Park J, Moon A, Hwang SC, Hong HS, Lee AL, Chang KH, Kim HK, Chin S
- KMID: 2150464
- J Korean Soc Radiol.
- 2016 Jan;74(1):61-65.
- doi: 10.3348/jksr.2016.74.1.61
Clear cell ependymoma (CCE) is a histological rare variant (1-5%) of ependymoma, which is distinguished from other histological subtypes by the presence of fusiform cells arrayed radially around small blood... -
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- Evaluation of Set-up Accuracy for Frame-based and Frameless Lung Stereotactic Body Radiation Therapy
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Ji Y, Chang KH, Cho B, Kwak J, Song SY, Choi EK, Lee SW
- KMID: 2151764
- Prog Med Phys.
- 2015 Dec;26(4):286-293.
- doi: 10.14316/pmp.2015.26.4.286
The purpose of this study was to evaluate the set up accuracy using stereotactic body frame and frameless immobilizer for lung stereotactic body radiation therapy (SBRT). For total 40 lung... -
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- Acute Disseminated Encephalomyelitis Presenting as Rhombencephalitis: An Atypical Case Presentation
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Hwang J, Lee AL, Chang KH, Hong HS
- KMID: 2175614
- Investig Magn Reson Imaging.
- 2015 Sep;19(3):186-190.
- doi: 10.13104/imri.2015.19.3.186
Acute disseminated encephalomyelitis (ADEM) is a demyelinating and inflammatory condition of the central nervous system, occurring predominantly in white matter. ADEM involving the rhombencephalon without affecting the white matter is... -
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- Evaluation of Dosimetric Leaf Gap (DLG) at Different Depths for Dynamic IMRT
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Chang KH, Kwak J, Cho B, Jeong C, Bae JB, Yoon SM, Lee SW
- KMID: 2069478
- Prog Med Phys.
- 2015 Sep;26(3):153-159.
- doi: 10.14316/pmp.2015.26.3.153
This study is to evaluate thedosiemtric leaf gap (DLG) at different depths for dynamic intensity-modulated radiation therapy (IMRT) in order to evaluate the absolute dose and dose distribution according to... -
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- Chordoid Glioma Originating in the Intrasellar and Suprasellar Regions: Case Report
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Hwang J, Lee A, Chang KH, Moon AR, Hwang SC, Hong HS
- KMID: 2175592
- Investig Magn Reson Imaging.
- 2015 Jun;19(2):117-121.
- doi: 10.13104/imri.2015.19.2.117
Chordoid glioma is a rare, low-grade brain neoplasm typically located in the third ventricle. Herein, we report an unusual case of histologically confirmed chordoid glioma located in the pituitary fossa... -
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