Korean J Hematol.  2012 Mar;47(1):3-5. 10.5045/kjh.2012.47.1.3.

Allogeneic stem cell transplantation for neuroblastoma

Affiliations
  • 1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Neuroblastoma
Stem Cell Transplantation
Stem Cells

Figure

  • Fig. 1 Representative case. The patient had 131I-meta-iodobenzylguanidine (MIBG) uptake at relapse after tandem HDCT/auto-SCT (A) (arrow head). He still had MIBG uptake arrows after conventional salvage treatment (B) (arrow head). RI alloSCT was given after high-dose 131I-MIBG treatment (18 mCi/kg). Regimen-related toxicity was minimal and rapid engraftment and complete donor chimerism were successfully achieved. Grade I acute graft-versus-host disease (GVHD) developed after withdrawal of immune suppression, and he had a moderate chronic GVHD. MIBG uptake was absent from day 90 and day 180 evaluations (C and D).


Reference

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