Korean J Med.
2009 Dec;77(6):787-792.
A case of pneumomediastinum combined with chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
- Affiliations
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- 1Department of Internal Medicine, Kosin University College of Medicine, Gospel Hospital, Busan, Korea. yas@ns.kosinmed.or.kr
Abstract
- Pulmonary complications are very common after allogeneic stem cell transplantation and are sometimes serious. Late-onset noninfectious pulmonary complications of chronic graft-versus-host disease (GVHD) after allogeneic stem cell transplantation include bronchiolitis obliterans and bronchiolitis obliterans with organizing pneumonia. Especially, bronchiolitis obliterans is correlated with GVHD. If they occur simultaneously, serious pulmonary and subcutaneous complications such as pneumomediastinum, subcutaneous emphysema, and pneumothorax can occur. We present the case of a 19-year-old man who had pneumomediastinum, subcutaneous emphysema, and pneumothorax with GVHD after allogeneic stem cell transplantation.
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