Korean J Dermatol.  2005 May;43(5):660-664.

Two Cases of Generalized Vitiligo after Allogeneic Stem Cell Transplantation

Affiliations
  • 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
  • 2Suncheon Severance Skin Clinic, Suncheon, Korea.
  • 3Woori Skin Clinic, Mokpo, Jeonnam, Korea. dermcha@hanmail.net

Abstract

Generalized vitiligo associated with allogeneic bone marrow or stem cell transplantation has rarely been reported. We experienced two cases of generalized vitiligo after allogeneic bone marrow and stem cell transplantation. The first patient was received an allogeneic bone marrow transplantation and subsequent allogeneic peripheral blood stem cell transplantation for severe aplastic anemia from his sister. The second patient underwent allogeneic bone marrow transplantation for acute myelogeneous leukemia from his sister. Generalized vitiligo developed after transplantation. Neither vitiligo nor evidences of autoimmune diseases were found in their stem cell donors. Vitiligo was effectively treated with narrow band UVB irradiation.

Keyword

Vitiligo; Allogeneic stem cell transplantation; Narrow band ultraviolet therapy

MeSH Terms

Anemia, Aplastic
Autoimmune Diseases
Bone Marrow
Bone Marrow Transplantation
Humans
Leukemia
Peripheral Blood Stem Cell Transplantation
Siblings
Stem Cell Transplantation*
Stem Cells*
Tissue Donors
Vitiligo*
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