- Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients
-
Lee M, Sim H, Ahn H, Ha J, Baek A, Jeon YJ, Son MY, Kim J
- KMID: 2465888
- Int J Stem Cells.
- 2019 Nov;12(3):474-483.
- doi: 10.15283/ijsc19075
In Parkinson’s disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as in vitro models. The advancement in the field of reprogramming technology has provided... -
- CITED
-
- Close
- SHARE
-
- Close
- Selective serotonin reuptake inhibitor escitalopram inhibits 5-HT₃ receptor currents in NCB-20 cells
-
Park YS, Sung KW
- KMID: 2461044
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):509-517.
- doi: 10.4196/kjpp.2019.23.6.509
Escitalopram is one of selective serotonin reuptake inhibitor antidepressants. As an S-enantiomer of citalopram, it shows better therapeutic outcome in depression and anxiety disorder treatment because it has higher selectivity... -
- CITED
-
- Close
- SHARE
-
- Close
- LGR5 and Downstream Intracellular Signaling Proteins Play Critical Roles in the Cell Proliferation of Neuroblastoma, Meningioma and Pituitary Adenoma
-
Hwang M, Han MH, Park HH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Min KW, Oh YH, Ko Y, Koh SH
- KMID: 2463717
- Exp Neurobiol.
- 2019 Oct;28(5):628-641.
- doi: 10.5607/en.2019.28.5.628
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) has been reported to play critical roles in the proliferation of various cancer cells. However, the roles of LGR5 in brain tumors and... -
- CITED
-
- Close
- SHARE
-
- Close
- Differential Clinical Significance of Neurotrophin-3 Expression according to MYCN Amplification and TrkC Expression in Neuroblastoma
-
Seo E, Kim JS, Ma YE, Cho HW, Ju HY, Lee SH, Lee JW, Yoo KH, Sung KW, Koo HH
- KMID: 2459423
- J Korean Med Sci.
- 2019 Oct;34(39):e254.
- doi: 10.3346/jkms.2019.34.e254
BACKGROUND: Neurotrophin-3 (NT-3), a member of the NT family, has only been considered an ancillary compound that provides anti-apoptotic benefits by inactivating tropomyosin receptor kinase C (TrkC)-induced apoptotic signals. However,... -
- CITED
-
- Close
- SHARE
-
- Close
- Deep learning for stage prediction in neuroblastoma using gene expression data
-
Park A, Nam S
- KMID: 2462044
- Genomics Inform.
- 2019 Sep;17(3):e30.
- doi: 10.5808/GI.2019.17.3.e30
Neuroblastoma is a major cause of cancer death in early childhood, and its timely and correct diagnosis is critical. Gene expression datasets have recently been considered as a powerful tool... -
- CITED
-
- Close
- SHARE
-
- Close
- Patterns of recurrence after radiation therapy for high-risk neuroblastoma
-
Jo JH, Ahn SD, Koh M, Kim JH, Lee SW, Song SY, Yoon SM, Kim YS, Kim SS, Park JH, Jung J, Choi EK
- KMID: 2460748
- Radiat Oncol J.
- 2019 Sep;37(3):224-231.
- doi: 10.3857/roj.2019.00353
PURPOSE: To investigate the patterns of recurrence in patients with neuroblastoma treated with radiation therapy to the primary tumor site. MATERIALS AND METHODS: We retrospectively analyzed patients with high-risk neuroblastoma managed... -
- CITED
-
- Close
- SHARE
-
- Close
- Riluzole Selective Antioxidant Effects in Cell Models Expressing Amyotrophic Lateral Sclerosis Endophenotypes
-
Sala G, Arosio A, Conti E, Beretta S, Lunetta C, Riva N, Ferrarese , Tremolizzo L
- KMID: 2457408
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):438-442.
- doi: 10.9758/cpn.2019.17.3.438
OBJECTIVE: Until recently, riluzole was the only drug licensed for amyotrophic lateral sclerosis (ALS). In spite of its efficacy, the mechanism of action remains elusive, and both blocking of glutamate... -
- CITED
-
- Close
- SHARE
-
- Close
- Mirror Syndrome Resulting from Metastatic Congenital Neuroblastoma to Placenta
-
Park SH, Namgoong J, Ko KN, Kim CJ, Lee PR, Jung E, Lee BS, Kim KS, Kim EA
- KMID: 2430224
- Perinatology.
- 2018 Dec;29(4):189-194.
- doi: 10.14734/PN.2018.29.4.189
Congenital neuroblastoma is a rare disease. Placental metastasis is extremely rare and poor prognosis has been reported in neonates. Mirror syndrome could occur in mother with placental metastasis with possibilities... -
- CITED
-
- Close
- SHARE
-
- Close
- Two Cases of Adjuvant Immunotherapy with Cytokine-Induced Killer Cells for Relapsed or Refractory Neuroblastoma
-
Choi JY, An HY, Hong KT, Hong C, Kang HJ, Shin HY
- KMID: 2435416
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):202-207.
- doi: 10.15264/cpho.2018.25.2.202
The treatment outcomes of relapsed or refractory neuroblastoma have been unsatisfactory till date. We reported two cases of adoptive immunotherapy using cytokine-induced killer (CIK) cells against relapsed or refractory neuroblastoma.... -
- CITED
-
- Close
- SHARE
-
- Close
- Two Pediatric Cases of Spontaneous Ruptured Solid Tumors Successfully Treated with Transcutaneous Arterial Embolization
-
Jo KJ, Yang EJ, Park KM, Kim JH, Jeon UB, Jang JY, Lim YT
- KMID: 2435415
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):197-201.
- doi: 10.15264/cpho.2018.25.2.197
Spontaneous rupture with internal bleeding of solid tumors has rarely been described at the time of diagnosis or during chemotherapy. This rare event must be regarded as a life threatening... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Significance of Random Urinary Vanillylmandelic Acid in Patients with Neuroblastoma
-
Park E, Park H, Cho H, Ma Y, Lee SY, Lee JW, Yoo KH, Sung KW, Koo HH
- KMID: 2435406
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):142-148.
- doi: 10.15264/cpho.2018.25.2.142
BACKGROUND: To evaluate the value of random urinary vanillylmandelic acid (VMA) as a surrogate marker for monitoring tumor response and predicting outcome in patients with neuroblastoma (NB). METHODS: Medical records of... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Infantile Nephrotic Syndrome associated with Neuroblastoma
-
Kim SH, Park HM, Lee JH, Kim H, Go H, Kim DY, Park YS
- KMID: 2435378
- Child Kidney Dis.
- 2018 Oct;22(2):91-96.
- doi: 10.3339/jkspn.2018.22.2.91
Nephrotic syndrome in the first year of life, characterized by renal dysfunction and proteinuria, is associated with a heterogeneous group of disorders. These disorders are often related to genetic mutations,... -
- CITED
-
- Close
- SHARE
-
- Close
- Value of SPECT/CT in Diagnostic I-131 MIBG Scintigraphy in Patients with Neuroblastoma
-
Theerakulpisut D, Raruenrom , Wongsurawat N, Somboonporn C
- KMID: 2422796
- Nucl Med Mol Imaging.
- 2018 Oct;52(5):350-358.
- doi: 10.1007/s13139-018-0532-y
PURPOSE: Diagnostic I-131 MIBG scintigraphy is an important imaging modality for evaluation of patients with neuroblastoma (NB) especially in centers where I-123 MIBG is not available. Single photon emission computed... -
- CITED
-
- Close
- SHARE
-
- Close
- Treatment Outcomes in Children and Adolescents with Relapsed or Progressed Solid Tumors: a 20-year, Single-Center Study
-
Cho HW, Lee JW, Ma Y, Yoo KH, Sung KW, Koo HH
- KMID: 2421401
- J Korean Med Sci.
- 2018 Oct;33(41):e260.
- doi: 10.3346/jkms.2018.33.e260
BACKGROUND: By estimating the survival rates and exploring prognostic factors in pediatric patients with relapsed or progressed solid tumors, our purpose was to generate background data for future studies. METHODS: We... -
- CITED
-
- Close
- SHARE
-
- Close
- Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
-
Park YS, Myeong SH, Kim IB, Sung KW
- KMID: 2419008
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):585-595.
- doi: 10.4196/kjpp.2018.22.5.585
Amitriptyline, a tricyclic antidepressant, is commonly used to treat depression and neuropathic pain, but its mechanism is still unclear. We tested the effect of amitriptyline on 5-hydroxytryptamine 3 (5-HT₃) receptor... -
- CITED
-
- Close
- SHARE
-
- Close
- Current Consensus on I-131 MIBG Therapy
-
Kayano D, Kinuya S
- KMID: 2418989
- Nucl Med Mol Imaging.
- 2018 Aug;52(4):254-265.
- doi: 10.1007/s13139-018-0523-z
Metaiodobenzylguanidine (MIBG) is structurally similar to the neurotransmitter norepinephrine and specifically targets neuroendocrine cells including some neuroendocrine tumors. Iodine-131 (I-131)-labeled MIBG (I-131 MIBG) therapy for neuroendocrine tumors has been performed... -
- CITED
-
- Close
- SHARE
-
- Close
- ALK Protein Expression Is Related to Neuroblastoma Aggressiveness But Is Not Independent Prognostic Factor
-
Lee JW, Park SH, Kang HJ, Park KD, Shin HY, Ahn HS
- KMID: 2411138
- Cancer Res Treat.
- 2018 Apr;50(2):495-505.
- doi: 10.4143/crt.2016.577
PURPOSE: In this study, anaplastic lymphoma kinase (ALK) mutation and amplification, ALK protein expression, loss of the nuclear alpha thalassemia/mental retardation syndrome X-linked (ATRX) protein, and telomerase reverse transcriptase (TERT)... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide
-
Lee AY, Choi JM, Lee MH, Lee J, Lee S, Cho EJ
- KMID: 2407805
- Nutr Res Pract.
- 2018 Apr;12(2):93-100.
- doi: 10.4162/nrp.2018.12.2.93
BACKGROUND/OBJECTIVE: Oxidative stress plays a key role in neuronal cell damage, which is associated with neurodegenerative disease. The aim of present study was to investigate the neuroprotective effects of perilla... -
- CITED
-
- Close
- SHARE
-
- Close
- Prenatally detected thoracic neuroblastoma
-
Park Y, Lee HJ, Jung YJ, Lee JH, Kwon JY, Kim YH
- KMID: 2420184
- Obstet Gynecol Sci.
- 2018 Mar;61(2):278-281.
- doi: 10.5468/ogs.2018.61.2.278
Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cells of the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracic... -
- CITED
-
- Close
- SHARE
-
- Close
- Excellent treatment outcomes in children younger than 18 months with stage 4 MYCN nonamplified neuroblastoma
-
Kim C, Choi YB, Lee JW, Yoo KH, Sung KW, Koo HH
- KMID: 2452041
- Korean J Pediatr.
- 2018 Feb;61(2):53-58.
- doi: 10.3345/kjp.2018.61.2.53
PURPOSE: Although the prognosis is generally good in patients with intermediate-risk neuroblastoma, no consensus has been reached on the ideal treatment regimen. This study analyzed treatment outcomes and toxicities in... -
- CITED
-
- Close
- SHARE
-
- Close
