Korean J Pediatr.  2008 Feb;51(2):214-218. 10.3345/kjp.2008.51.2.214.

Palliative effect of (131)I-MIBG in relapsed neuroblastoma after autologous peripheral blood stem cell transplantation

• Lee YJ
• Hah JO

• KMID: 2280231
• DOI: http://doi.org/10.3345/kjp.2008.51.2.214

Abstract

Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine ((131)I-MIBG) therapy is an alternative approach to treat stage IV neuroblastoma. We report the palliative effect of (131)I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. (131)I-MIBG is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival.

Keyword

Relapsed neuroblastoma; (131)I-MIBG; Palliative therapy

MeSH Terms

Neuroblastoma
Palliative Care
Peripheral Blood Stem Cell Transplantation