Korean J Dermatol.  2002 Mar;40(3):258-265.

Clinical Manifestations of Dermatomyositis

• Chung JH
• Seo PG

Abstract

BACKGROUND: Dermatomyositis (DM) is a rare inflammatory musculocutaneous disease of presumed autoimmune origin.
OBJECTIVE
The purpose of our study was to analyze the clinical manifestations of DM,
METHODS
A retrospective study of 18 patients with DM is analyzed.
RESULTS
1. The range of age was from 3 to 72 years, and the most frequent age group was 46-60 (38.9%). Male to female ratio was 1:8. 2. Among the 18 patients, 61.1% was classified as DM, 38.9% as amyopathic dermatomyositis (ADM), 3. Skin rash was noted 100%, itching 72.2%, proximal muscle weakness 61.1%, myalgia 38.2%, arthralgia 22.2%, hair loss 22.2%, Raynaud's phenomenon 22.2%. Arnong the skin rash, Gottron's sign was most frequent (83.3%), followed by heliotrope rash (72.2%), Gottron's papule (66.6%). 4. Serum CPK level was elevated in 38.9%, LDH 88.9%, SGOT 44.4%, SGPT 33.3%, and ESR 61.1%. 5. DM patients were treated with prednisolone 400mg/kg/day and hydroxychloroquine 400mg/day (childhood 5mg/kg/day) for 4~8 weeks. Four patients who had severe skin manifestations and pruritus added methotrexate. Four ADM patients were treated with hydroxychloroquine 5mg/kg/day only. Two ADM patients were added prednisolone 1mg/kg/day for 6 weeks.

Keyword

Dermatomyositis; Amyopathic; Dermatomyositis

MeSH Terms

Alanine Transaminase
Arthralgia
Aspartate Aminotransferases
Dermatomyositis*
Exanthema
Female
Hair
Humans
Hydroxychloroquine
Male
Methotrexate
Muscle Weakness
Myalgia
Prednisolone
Pruritus
Retrospective Studies
Skin Manifestations
Alanine Transaminase
Aspartate Aminotransferases
Hydroxychloroquine
Methotrexate
Prednisolone