- Evaluation of Drug-Induced Liver Injury Developed During Hospitalization Using Electronic Health Record (EHR)-Based Algorithm
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Kang Y, Kim SH, Park SY, Park BY, Lee JH, An J, Won HK, Song WJ, Kwon HS, Cho YS, Moon HB, Shim JH, Yang MS, Kim TB
- KMID: 2471227
- Allergy Asthma Immunol Res.
- 2020 May;12(3):430-442.
- doi: 10.4168/aair.2020.12.3.430
PURPOSE: The incidence of drug-induced liver injury (DILI) has been increasing; however, few algorithms are available to identify DILI in electronic health records (EHRs). We aimed to identify and evaluate... -
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- Combination of Methotrexate and Leflunomide for Adult-onset Still's Disease: A Case Report and Literature Review
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Lee EE, Kim MJ, Song YW, Park JK
- KMID: 2471953
- J Rheum Dis.
- 2020 Apr;27(2):116-119.
- doi: 10.4078/jrd.2020.27.2.116
The treatment of adult-onset Still's disease (AOSD) aims to control systemic inflammation and prevent organ damage. Systemic inflammation can be controlled with corticosteroid (CS) monotherapy in most cases. However, symptoms... -
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- Enzymes involved in folate metabolism and its implication for cancer treatment
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Kim SE
- KMID: 2471876
- Nutr Res Pract.
- 2020 Apr;14(2):95-101.
- doi: 10.4162/nrp.2020.14.2.95
BACKGROUND/OBJECTIVES: Folate plays a critical role in DNA synthesis and methylation. Intracellular folate homeostasis is maintained by the enzymes folylpolyglutamate synthase (FPGS) and γ-glutamyl hydrolase (GGH). FPGS adds glutamate residues... -
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- The Effects of Systemic Psoriasis Therapies on the C-Reactive Protein and the Neutrophil-Lymphocyte Ratio
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Aktaş Karabay E, Aksu Çerman A, Demir D, Kıvanç Altunay I
- KMID: 2461982
- Ann Dermatol.
- 2019 Dec;31(6):601-610.
- doi: 10.5021/ad.2019.31.6.601
BACKGROUND: Currently, no generally accepted laboratory marker for monitorizing the disease activity and therapy response of psoriasis is known. OBJECTIVE: The aim of the study is to evaluate the effects of... -
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- Methotrexate-Induced Leukoencephalopathy Presenting Like Acute Stroke
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Ha WS, Choi BK, Koo Y, Nam HS
- KMID: 2464152
- J Korean Neurol Assoc.
- 2019 Nov;37(4):417-419.
- doi: 10.17340/jkna.2019.4.17
No abstract available. -
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- Effect of lutein on methotrexate-induced oxidative lung damage in rats: a biochemical and histopathological assessment
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Mammadov R, Suleyman B, Akturan S, Cimen FK, Kurt N, Suleyman Z, Malkoc I
- KMID: 2463486
- Korean J Intern Med.
- 2019 Nov;34(6):1279-1286.
- doi: 10.3904/kjim.2018.145
BACKGROUND/AIMS: This study aimed to investigate the effect of lutein on methotrexate (MTX)-induced pulmonary toxicity in rats biochemically and histopathologically. METHODS: The rats in the MTX + lutein (MTXL, n =... -
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- A Case of Recurrent Rosai-Dorfman Disease Successfully Treated with 2-Chlorodeoxyadenosine (Cladribine)
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Cho MH, Jung HJ, Han JH, Park JE
- KMID: 2464258
- Clin Pediatr Hematol Oncol.
- 2019 Oct;26(2):99-104.
- doi: 10.15264/cpho.2019.26.2.99
Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease (RDD), is a rare histiocytic disorder of unknown etiology. Most patients with RDD have spontaneous remission, but in some patients,... -
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- Efficacy of Slow Rate Ventriculolumbar Perfusion Chemotherapy for Leptomeningeal Carcinomatosis: Interim Result of a Phase II Study
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Choi YH, Gwak HS, Joo J, Kwon JW, Shin SH, Yoo H, Lee JH, Youn JH
- KMID: 2461180
- Brain Tumor Res Treat.
- 2019 Oct;7(2):85-91.
- doi: 10.14791/btrt.2019.7.e33
BACKGROUND: To evaluate the efficacy of modified ventriculolumbar perfusion (VLP) chemotherapy with methotrexate on leptomeningeal carcinomatosis in terms of symptomatic response and side effects. METHODS: Previous infusion rate of 20 mL/h... -
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- A Case of Autoimmune Sensorineural Hearing Loss Responding to Cytotoxic Agent
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Lee YW, Lee J, Kim MB, Chang SO
- KMID: 2457195
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Aug;62(8):470-474.
- doi: 10.3342/kjorl-hns.2018.00549
Autoimmune sensorineural hearing loss is a rare disease characterized by bilateral sensorineural hearing loss, some in a progressive pattern and others in idiopathic or fluctuating pattern, often accompanied by vestibular... -
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- Comparative Study of Clinical Characteristics according to Therapeutic Efficacy and Drug Survival of Cyclosporine or Methotrexate in Psoriasis Vulgaris
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Lee HS, Kwon SH, Lee ES
- KMID: 2451491
- Ann Dermatol.
- 2019 Aug;31(4):469-472.
- doi: 10.5021/ad.2019.31.4.469
No abstract available. -
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- Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis
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Baek HJ, Lim MJ, Park W, Park SH, Shim SC, Yoo DH, Kim HA, Lee SK, Lee YJ, Park YE, Cha HS, Song YW
- KMID: 2457323
- Korean J Intern Med.
- 2019 Jul;34(4):917-931.
- doi: 10.3904/kjim.2017.159
BACKGROUND/AIMS: To investigate the efficacy and safety of tocilizumab (TCZ) humanized anti-interleukin-6 receptor monoclonal antibody, in Korean patients with active rheumatoid arthritis (RA) refractory to conventional disease modifying anti-rheumatic drugs... -
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- Treatment of primary cutaneous anaplastic large cell lymphoma
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Baik BS, Lee WS, Ji SY, Park KS, Yang WS, Kim SY
- KMID: 2453156
- Arch Craniofac Surg.
- 2019 Jun;20(3):207-211.
- doi: 10.7181/acfs.2018.02201
Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare subtype of primary cutaneous lymphoma with a favorable prognosis. Primary cutaneous CD30+ lymphoproliferative disorders, which include C-ALCL and lymphomatoid papulosis,... -
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- Delayed Elimination After High-dose Methotrexate in Pediatric Patients with Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma
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Yoon HW, Ree YS, Song HS, Kim JS, Son ES
- KMID: 2452858
- Korean J Clin Pharm.
- 2019 Jun;29(2):101-108.
- doi: 10.24304/kjcp.2019.29.2.101
BACKGROUND: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases... -
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- Primary central nervous system lymphoma with intramedullary spinal cord involvement mimicking inflammatory demyelinating disease
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Kim H, Nam TS, Levy M, Lee KH, Kim J, Lee SJ
- KMID: 2452828
- J Neurocrit Care.
- 2019 Jun;12(1):55-63.
- doi: 10.18700/jnc.190083
BACKGROUND: Spinal cord involvement of primary central nervous system lymphoma (PCNSL) is rare in a young immunocompetent patient and can be misdiagnosed as an inflammatory demyelinating disease (IDD) of the... -
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- Primary Intraocular T-cell Lymphoma
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Shin YI, Kim JM, Lee JJ, Kim JY, Kim J, Jo YJ
- KMID: 2449714
- J Korean Ophthalmol Soc.
- 2019 Jun;60(6):594-599.
- doi: 10.3341/jkos.2019.60.6.594
PURPOSE: Intraocular lymphoma can be divided into primary and secondary usually involving B-cell lymphoma. Intraocular T-cell lymphoma is mostly secondary lymphoma while primary intraocular T-cell lymphoma is extremely rare. We... -
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- A rare case of ovarian vein thrombosis in a gestational trophoblastic neoplasia patient
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Kim IY, Kim SH, Hwang IT, Ha JG, Cha JH
- KMID: 2445079
- Obstet Gynecol Sci.
- 2019 May;62(3):190-193.
- doi: 10.5468/ogs.2019.62.3.190
Ovarian vein thrombosis (OVT) is a rare disease with complications that can be life-threatening. An ovarian vein thrombus in a gestational trophoblastic neoplasia (GTN) is an extremely rare condition that... -
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- Recent medical therapy for psoriasis
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Youn SW
- KMID: 2441069
- J Korean Med Assoc.
- 2019 Mar;62(3):176-180.
- doi: 10.5124/jkma.2019.62.3.176
Psoriasis is a chronic inflammatory disease. Medical therapy is the mainstay of the management of psoriasis, and the main target of psoriasis treatment is immunological dysregulation. Cyclosporine and methotrexate, the... -
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- Severe recurrent nocturnal hypoglycemia during chemotherapy with 6-mercaptopurine in a child with acute lymphoblastic leukemia
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Cho EM, Moon JE, Lee SJ, Ko CW
- KMID: 2432275
- Ann Pediatr Endocrinol Metab.
- 2018 Dec;23(4):226-228.
- doi: 10.6065/apem.2018.23.4.226
Various endocrine dysfunctions occur during chemotherapy, including hypoglycemia. However, reports of hypoglycemia associated with 6-mercaptopurine (6-MP) are rare. Herein, we report an 8-year-old boy with severe symptomatic hypoglycemia likely due... -
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- Treatment results of the second-line chemotherapy regimen for patients with low-risk gestational trophoblastic neoplasia treated with 5-day methotrexate and 5-day etoposide
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Kanno T, Matsui H, Akizawa Y, Usui H, Shozu M
- KMID: 2431234
- J Gynecol Oncol.
- 2018 Nov;29(6):e89.
- doi: 10.3802/jgo.2018.29.e89
OBJECTIVE: Highly effective chemotherapy for patients with low-risk gestational trophoblastic neoplasia (GTN) is associated with almost a 100% cure rate. However, 20%–30% of patients treated with chemotherapy need to change... -
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- Rapid onset of efficacy predicts response to therapy with certolizumab plus methotrexate in patients with active rheumatoid arthritis
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Kang YM, Park YE, Park W, Choe JY, Cho CS, Shim SC, Bae SC, Suh CH, Cha HS, Koh EM, Song YW, Yoo B, Lee SS, Park MC, Lee SH, Arendt C, Koetse W, Lee SK
- KMID: 2426407
- Korean J Intern Med.
- 2018 Nov;33(6):1224-1233.
- doi: 10.3904/kjim.2016.213
BACKGROUND/AIMS: The objective of this study was to determine the efficacy and safety of add-on therapy with certolizumab pegol (CZP) in active rheumatoid arthritis (RA) patients of a single ethnicity. METHODS:... -
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