J Korean Ophthalmol Soc.  1999 Sep;40(9):2401-2410.

Antibiotic Susceptibilities of Ocular Isolates from Patients with Bacterial Ke ratitis: A Multi-center Study

• Hahn YH
• Lee SJ
• Hahn TW
• Tchah H
• Kim JC

Abstract

This multi-center study was performed prospectively to evaluate the causative organisms and antibiotic sensitivity of isolates in bacterial keratitis from April 1995 to December 1998. Total number of infectious keratitis was 1002 cases. Among them,279 cases were confirmed with bacterial keratitis and 314 strains were identified. Major causative organisms of bacterial keratitis were Pseudomonas aeruginosa 121 strains (38.54%), coagulase negative staphylococcus (CNS) 34 strains (10.83%), Streptococcus pneumoniae 19 strains (6.81%), Staphylococcus aureus 18 strains (5.73%), and Serratia marscence 16 strains (5.10%). P.aeruginosa was highly sensitive to ciprofloxacin, ceftazidime, piperacillin, cefoperazone, imipenem,tobramicin,and gentamycin. Coagulase negative streptococcus showed high sensitivity to vancomycin, teicoplanin, clindamycin, and ciplofloxacin, but low sensitivity to penicillin and gentamycin. In conclusion, the choice of the effective antibiotics in the treatment of bacterial keratitis were essential to decrease resistant bacterial strains.

Keyword

Antibiotics; Bacterial keratitis; Sensitivity test

MeSH Terms

Anti-Bacterial Agents
Cefoperazone
Ceftazidime
Ciprofloxacin
Clindamycin
Coagulase
Gentamicins
Humans
Keratitis
Penicillins
Piperacillin
Prospective Studies
Pseudomonas aeruginosa
Serratia
Staphylococcus
Staphylococcus aureus
Streptococcus
Streptococcus pneumoniae
Teicoplanin
Vancomycin
Anti-Bacterial Agents
Cefoperazone
Ceftazidime
Ciprofloxacin
Clindamycin
Coagulase
Gentamicins
Penicillins
Piperacillin
Teicoplanin
Vancomycin