J Korean Orthop Res Soc.  2014 Jun;17(1):13-20. 10.0000/jkors.2014.17.1.13.

Usefulness of the Biochemical Markers in the Elderly Hip Fracture Patients

• Yun HH
• Yoon JR
• Lee YI
• Yun SH
• Kim KH

• KMID: 2199038
• DOI: http://doi.org/10.0000/jkors.2014.17.1.13

Abstract

PURPOSE
The authors evaluated the usefulness of the biochemical markers in the elderly hip fracture patients.
MATERIALS AND METHODS
Eighty-two hip fractures above 65 years old were enrolled in this study. Serum level of C-telopeptide, osteocalcin, parathyroid hormone, 25-hydroxyvitamin D, calcium were checked and bone mineral density was assessed by DXA.
RESULTS
83% vitamin D deficiency and 43% calcium insufficiency were observed. There were statistically significance between C-telopeptide and osteocalcin, calcium and 25-hydroxyvitamin D, and calcium and DXA results in the Chi-Square test. Spearmann correlation coefficient results showed that there were statically significant correlations between C-telopeptide and osteocalcin, calcium and DXA results. In the multiple logistic regression analysis results, calcium had the statically significant correlations with DXA results.
CONCLUSION
There was correlation between bone turnover markers and vitamin D deficiency, and calcium insufficiency was observed in the elderly hip fracture patients.

Keyword

Hip; Hip fracture; Osteoporosis; Biochemical marker; Bone mineral density

MeSH Terms

Aged*
Biomarkers*
Bone Density
Calcium
Hip Fractures
Hip*
Humans
Logistic Models
Osteocalcin
Osteoporosis
Parathyroid Hormone
Vitamin D Deficiency
Calcium
Osteocalcin
Parathyroid Hormone