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Seasonal Variations and Common Places of Hip Fractures in Elderly Patients: Nine Year Consecutive Survey

Choi KA, Ha YC, Lee KH

Background: Fall prevention is important for reducing hip fractures. The aim of this study was to determine the relationship between variables related to hip fractures according to sex and season. Methods:...
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Different Pattern of T-Score Discordance between Patients with Atypical Femoral Fracture and Femur Neck Fracture

Yoon BH, Park JW, Lee CW, Koh YD

Background: Our study evaluated the prevalence and pattern of T-score discordance between the spine and hip in Korean patients with atypical femoral fracture (AFF) and femur neck fracture (FNF). Methods: A...
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Trabecular Bone Score and Central Quantitative Computed Tomography for the Prediction of Vertebral Fragility Fractures in Postmenopausal Women

Ryang S, Jeon YK, Goh TS, Kim IJ, Kim K

Background: We aimed to investigate whether densitometry results and volumetric bone mineral density (vBMD) can predict vertebral fragility fractures (VFF) in postmenopausal women. Methods: We enrolled 271 postmenopausal women aged >45...
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Bone Mineral Density in Patients with Pediatric Inflammatory Bowel Disease Using Dual Energy X-Ray Absorptiometry

Isa HM, Ezzaldin AA, Alabbasi MM, ALaazmi NH, Masood AS, Alabbasi HM

Background: Inflammatory bowel disease (IBD) is a chronic inflammatory immune-mediated condition that affects the gastrointestinal system and alters bone growth and bone mineral density (BMD). Here we aimed to study...
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Best Laboratory Screening in Diagnosing Secondary Osteoporosis and Fracture Risk Assessment Tool and the National Osteoporosis Guideline Group Performance in Determining Clinical Risk: A Cross-Sectional Evaluation of the Bone Health in Postmenopausal Brazilian Women

Steiner ML, Crotti GP, Teodoro JD, Ikeda RK, Strufaldi R, Fernandes CE, Pompei LdM

Background: Identifying postmenopausal women with a high risk of having osteoporosis and fractures is a current challenge. This study aimed to assess the diagnostic performance of biochemical tests in identifying...
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Health-Related Quality of Life in Osteoporosis Patients with and without Fractures in Tehran, Iran

Rajabi M, Ostovar A, Sari AA, Sajjadi-Jazi SM, Mousavi A, Larijani B, Fahimfar N, Daroudi R

Background: This study aimed to measure the health-related quality of life (HRQOL) of patients with osteoporosis with and without fractures in Tehran, the capital city of Iran. Methods: We surveyed a...
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Cementless Hip Arthroplasty Using a Long Double-Tapered Rectangular Stem in Patients with Osteoporotic Proximal Femoral Fractures or Reoperation

Lee HJ, Kim HS, Yoo JJ

Purpose: This study examined the clinical and radiological results of cementless hip arthroplasty using a long double-tapered rectangular stem in cases with osteoporotic proximal femoral fractures or in reoperation cases. Materials...
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Cardiovascular Impact of Calcium and Vitamin D Supplements: A Narrative Review

Zarzour F, Didi A, Almohaya M, Kendler D

Calcium and vitamin D play an important role in mineral homeostasis and the maintenance of skeletal health. Calcium and vitamin D supplements have been widely used for fracture prevention in...
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Big Data Research in the Field of Endocrine Diseases Using the Korean National Health Information Database

Cho SW, Kim JH, Choi HS, Ahn HY, Kim MK, Rhee EJ

The Korean National Health Information Database (NHID) contains big data combining information obtained from the National Health Insurance Service and health examinations. Data are provided in the form of a...
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The Impact of Persistent Low Weight Status on the Occurrence of Vertebral Fractures: A Nationwide PopulationBased Cohort Study

Park SM, Park J, Han S, Jang HD, Hong JY, Han K, Kim HJ, Yeom JS

Background: Although, being underweight is commonly associated with osteoporosis and sarcopenia, its association with vertebral fractures (VFs), is less well researched. We investigated the influence of cumulative, chronic periods of...
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Bone Health-Related Nutritional Knowledge and its Association with Calcium-Related Dietary Behaviors and Nutrition Education of Women in their 20s and 30s

Choi ES, Park CY

Osteoporosis is a major health problem confronting middle-aged women today. Enhancing calcium intake in early adulthood can increase the rate of calcium gain in bone. In this study, we investigated...
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MicroRNA-181a-5p Curbs Osteogenic Differentiation and Bone Formation Partially Through Impairing Runx1-Dependent Inhibition of AIF-1 Transcription

Liu J, Chang X, Dong D

Background: Evidence has revealed the involvement of microRNAs (miRNAs) in modulating osteogenic differentiation, implying the promise of miRNA-based therapies for treating osteoporosis. This study investigated whether miR-181a-5p influences osteogenic differentiation...
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Fragility Fractures of the Pelvis and Sacrum

Lee SW, Kim JY

The incidence of fragility fractures of the pelvis (FFP) has increased significantly due to the aging popu-lation and improved diagnostic modalities. The evaluation and treatment of these patients differ from...
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Positive Effects of Biologics on Osteoporosis in Rheumatoid Arthritis

Kim Y, Kim GT

Osteoporosis is a systemic skeletal disorder that causes vulnerability of bones to fracture owing to reduction in bone density and deterioration of the bone tissue microstructure. The prevalence of osteoporosis...
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Trabecular Bone Score as a Risk Factor of Major Osteoporotic Fracture in Postmenopausal Women: The First Study in Thailand

Therdyothin A, Amphansap T

Objectives: To compare the trabecular bone score (TBS) between Thai postmenopausal women with and without major osteoporotic fracture, and to determine whether TBS is associated with fracture risk. Methods: All postmenopausal...
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Identification of novel susceptibility genes associated with bone density and osteoporosis in Korean women

Kim BY, Kim DW, Park E, Kim J, Lee CG, Jin HS, Jeong SY

Purpose: Osteoporosis is a common calcium and metabolic skeletal disease which is characterized by decreased bone mass, microarchitectural deterioration of bone tissue and impaired bone strength, thereby leading to enhanced...
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Management of Osteoporotic Vertebral Fracture: Review Update 2022

Jang HD, Kim EH, Lee JC, Choi SW, Kim HS, Cha JS, Shin BJ

A vertebral fracture is the most common type of osteoporotic fracture. Osteoporotic vertebral fractures (OVFs) cause a variety of morbidities and deaths. There are currently few “gold standard treatments” outlined...
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Molecular mechanisms of hederagenin in bone formation

Seo HJ, Kwun IS, Kwon J, Sim Y, Cho YE

Purpose: Osteoporosis is characterized by structural deterioration of the bone tissue because of the loss of osteoblastic activity or the increase in osteoclastic activity, resulting in bone fragility and an...
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Up-to-Date Knowledge on Osteoporosis Treatment Selection in Postmenopausal Women

Jeong HG, Kim MK, Lim HJ, Kim SK

The concept of a super-aged society has led to a steady increase in the average lifespan and hence, interest in a healthy life has increased. Aging is a major risk...
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A Vitronectin-Derived Peptide Restores Ovariectomy-Induced Bone Loss by Dual Regulation of Bone Remodeling

Kang HK, Park CY, Jung SY, Jo SB, Min BM

BACKGROUND: Bone remodeling is tightly regulated through bone resorption and bone formation; imbalances in bone remodeling can cause various pathological conditions such as osteoporosis. Antiresorptive agents commonly used for treating...
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