Korean J Dermatol.
2003 Nov;41(11):1513-1516.
A Case of Paraneoplastic Acral Vascular Syndrome Accompanied with Metastatic Adenocarcinoma
- Affiliations
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- 1Department of Dermatology, Jeju National University, College of Medicine, Jeju, Korea. rulidroxim@hanmail.net
- 2Department of Rheumatology, Jeju National University, College of Medicine, Jeju, Korea.
- 3Department of Dermatology, Hallym University, College of Medicine, Seoul, Korea.
Abstract
- Paraneoplastic acral vascular syndrome(PAVS) designates the various acral ischemic changes in the elderly patients with occult cancer in the absence of usual causative conditions such as connective tissue disease, hemostatic abnormalities, cardiovascular disease, metabolic disease, peripheral neuropathy, trauma, emboli, and drugs. The common clinical presentation in PAVS is as follows; Raynaud phenomenon, digital gangrene, pulp ulceration, splinter hemorrhage, and acrosclerosis. Most common neoplastic origin of PAVS has been known to be adenocarcinoma occurring in the lung, ovary or uterus. Until now, PAVS have been rarely reported in the Korean literature. We herein report a rare case of PAVS associated with metastatic adenocarcinoma of unknown primary origin.
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