J Korean Cancer Assoc.  1998 Aug;30(4):737-742.

A Case of Paraneoplastic Membranous Nephropathy Associated with Adenocarcinoma of the Lung

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Hallym University.
  • 2Department of Anatomical Pathology, College of Medicine, Hallym University.
  • 3Department of Anatomical Pathology, College of Medicine Seoul National University, Seoul, Korea.

Abstract

The paraneoplastic nephrotic syndrome can be diagnosed by clinical and immunologic features. We have had a case of paraneoplastic nephrotic syndrome in the patients with aadeno-carcinoma of the lung, whose diagnosis was made by excluding other causes of nephrotic syndrome. The type of renal lesion was membranous glomerulopathy which commonly occurs in carcinoma. The quantity of proteinuria in this patient had decreased according to the improvement of lung cancer with combination chemotherapy. After fourth chemotherapy he was refractory to treatment, and unfortunately he had passed away with cardiac tamponade.

Keyword

Adenocarcinoma of the lung; Membranous nephropathy; Paraneoplastic syndrome

MeSH Terms

Adenocarcinoma*
Cardiac Tamponade
Diagnosis
Drug Therapy
Drug Therapy, Combination
Glomerulonephritis, Membranous*
Humans
Lung Neoplasms
Lung*
Nephrotic Syndrome
Paraneoplastic Syndromes
Proteinuria
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