Korean J Infect Dis.
1998 Dec;30(6):527-531.
The Methicillin-Resistance Rate of Staphylococcus aureus Isolatd from Anterior Nares of Healthy Adults in the Community
- Affiliations
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- 1Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 2Departments of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- BACKGROUND
About 80% of nosocomial Stap hylococcus aureus isolates demonstrate methicillin resistance in Korea. To assess the prevalence of methicillin- resistant S. aureus (MRSA) in the community, we screened the nasal S. aureus isolates from healthy adults.
METHODS
Nasal cultures were collected from healthy adults without known risk factors for acquisition of MRSA. Antimicrobial susceptibility of S. aureus isolates against oxacillin were determined using the E- test and the disk diffusion method. Methicillin resistant isolates were tested for the mecA gene by polymerase chain reaction.
RESULTS
Total 689 subjects were studied. The point prevalence of S. aureus was 33% (227/689). Sixteen isolates of S. aureus grew on the MRSA screening plates(MAO), of which 5(2.2%) were resistant to oxacillin and positive for the mecA gene.
CONCLUSION
Less than 5% (95% CI; 1 ~5%) of the nasal S. aureus isolates in the community were methicillin-resistant.
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