Korean J Nephrol.  2006 May;25(3):447-451.

Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration: Report of Two Cases

Affiliations
  • 1Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ygkim@smc.samsung.co.kr

Abstract

Continuous renal replacement therapy (CRRT) has been used increasingly for the management of renal failure in hemodynamically unstable and critically ill patients. CRRT requires anticoagulation, usually with heparin, to prevent clotting in the extracorporeal circuit. Systemic heparinization is associated with a high rate of bleeding when used during CRRT in critically ill patients. We applied regional citrate anticoagulation for CRRT to two critically ill patients with high bleeding risk using calcium containing commercial solutions. We conclude that regional citrate anticoagulation with commercial calcium containing solution can be used alternative to heparin for CRRT in patients with high bleeding risk.

Keyword

Continuous renal replacement therapy; Heparin; Regional citrate anticoagulation

MeSH Terms

Calcium
Citric Acid*
Critical Illness
Hemodiafiltration*
Hemorrhage
Heparin
Humans
Renal Insufficiency
Renal Replacement Therapy
Calcium
Citric Acid
Heparin
Full Text Links
  • KJN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr