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Initial Preserved Renal Function as a Predictor of Favorable Renal Response to Rituximab in Refractory or Relapsing Lupus Nephritis: A Single-center Cohort Study in Korea

Choi SJ, Ahn SM, Oh JS, Hong S, Lee CK, Yoo B, Kim YG

Objective Previous studies investigating the beneficial effect of rituximab on lupus nephritis (LN) reported controversial results. There have been few reports of renal response to rituximab according to renal function....
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Optimization of Cultivation and Extraction Conditions of Pupae-Cordyceps for Cordycepin Production

Turk A, Kim BS, Ko SM, Yeon SW, Ryu SH, Kim YG, Hwang BY, Lee MK

Cordycepin is a characteristic bioactive compound of Cordyceps militaris with various beneficial effects. Cordyceps grows on both grains and insects, and the content of cordycepin varies depending on the cultivation...
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Inherited arrhythmia syndrome predisposing to sudden cardiac death

Kim YG, Oh SK, Choi HY, Choi JI

Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, and is reported to be a more prevalent cause of SCD in Asia...
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Pregnancy outcomes in Korean women with ankylosing spondylitis

Park EH, Lee JS, Kim YJ, Lee SM, Jun JK, Lee EB, Kim YG

Background/Aims: Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS. Methods:...
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Impact of carotid atherosclerosis in CHA2DS2-VASc-based risk score on predicting ischemic stroke in patients with atrial fibrillation

Cho DH, Choi JI, Choi J, Kim YG, Oh SK, Kook H, Lee KN, Shim J, Park SM, Shim WJ, Kim YH

Background/Aims: Vascular disease is an established risk factor for stroke in patients with atrial fibrillation (AF), which is included in CHA2DS2-VASc score. However, the role of carotid atherosclerosis remains to...
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Biologic therapies for the treatment of ankylosing spondylitis

Ahn SM, Kim YG

Ankylosing spondylitis (AS) is a chronic inflammatory disease predominantly affecting the axial skeleton. AS treatment aims to reduce pain and inflammation and maintain functional capacity. Nonsteroidal anti-inflammatory drugs are the...
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A Case of Verruciform Xanthoma of the Sole

Seo HM, Jang JW, Park SK, Jung YJ, Kim TL, Kim YG, Kim JS

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SARS-CoV-2 Omicron Mutation Is Faster than the Chase: Multiple Mutations on Spike/ACE2 Interaction Residues

Kim S, Nguyen TT, Taitt AS, Jhun H, Park HY, Kim SH, Kim YG, Song EY, Lee Y, Yum H, Shin KC, Choi YK, Song CS, Yeom SC, Kim B, Netea M, Kim S

Recently, a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (B.1.1.529) Omicron variant originated from South Africa in the middle of November 2021. SARS-CoV-2 is also called coronavirus disease 2019...
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Comparison of Changes in Emotional and Behavioral Characteristics of Students Referred to One Hospital-Linked Wee Center after COVID-19 Outbreak

Koo S, Lee Y, Jung HS, Kim H, Kim YG, Seo MJ, Seo WS

  • KMID: 2522088
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Oct;27(3):180-189.
Objectives:The purpose of this study was to identify the change in the reasons for referrals before and after the COVID-19 outbreak among students who were referred to the one hospital-linked...
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Non-invasive diagnosis for acute rejection using blood mRNA signature reflecting allograft status in kidney transplantation

Han A, Seo JW, Kim YG, Moon JY, Lee SH

Background: Despite improvements in immunosuppressive therapy over the years, acute rejection (AR) episodes that required treatment are still a significant risk factor for poor graft outcomes. Monitoring renal graft status...
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Prognostic factors of renal outcomes after heart transplantation: a nationwide retrospective study

Jeon J, Park H, Kim Y, Kang D, Lee JE, Huh W, Kim YG, Kim DJ, Cho J, Jang HR

Background: Renal dysfunction after heart transplantation (HT) is associated with poor survival. Predicting renal outcome after HT is a substantial but difficult issue. We investigate the predictive factors of renal...
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The 10-Year Trend of Out-of-hospital Cardiac Arrests: a Korean Nationwide Population-Based Study

Roh SY, Choi JI, Park SH, Kim YG, Shim J, Kim JS, Han KD, Kim YH

Background and Objectives It is crucial to understand the exact public health burden of out-of-hospital cardiac arrest (OHCA) cases; this is presently unknown since sufficient episodes are not reported in registry...
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Codeless Deep Learning of COVID-19 Chest X-Ray Image Dataset with KNIME Analytics Platform

An JY, Seo H, Kim YG, Lee KE, Kim S, Kong HJ

Objectives: This paper proposes a method for computer-assisted diagnosis of coronavirus disease 2019 (COVID-19) through chest X-ray imaging using a deep learning model without writing a single line of code...
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Treatment Response to Idiopathic Retroperitoneal Fibrosis-associated Hydronephrosis With a Focus on IgG4/IgG3 Serum Concentration Ratio

Choi SJ, Oh JS, Hong S, Lee CK, Yoo B, Hong B, Kim YG

Objective. Hydronephrosis, a common complication of idiopathic retroperitoneal fibrosis (iRPF), may lead to poor renal outcomes unless resolved in a timely manner. IgG4-related diseases characterized by elevated serum IgG4 levels...
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Nontuberculous mycobacterial infection in rheumatoid arthritis patients: a single-center experience in South Korea

Lim DH, Kim YG, Shim TS, Jo KW, Ghang B, Ahn SM, Hong S, Lee CK, Yoo B

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Efficacy and Safety of Rituximab in Korean Patients with Refractory Inflammatory Myopathies

Ahn GY, Suh CH, Kim YG, Park YB, Shim SC, Lee SH, Lee SS, Bae SC, Yoo DH

Background: Rituximab (RTX), a monoclonal antibody that selectively binds to CD20+ B cells, showed favorable outcomes in patients with idiopathic inflammatory myopathies (IIM) in small case series, but the evidence...
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Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke

Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y

  • KMID: 2506534
  • Exp Neurobiol.
  • 2020 Aug;29(4):300-313.
  • doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy...
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A Close Relationship between Non-Alcoholic Fatty Liver Disease Markerand New-Onset Hypertension inHealthy Korean Adults

Roh JH, Park JH, Lee H, Yoon YH, Kim M, Kim YG, Park GM, Lee JH, Seong IW

Background and Objectives: Nonalcoholic fatty liver disease (NAFLD) is an excessiveaccumulation of fat into the liver as a result of increased inflammation and insulin resistance.Although there can be common pathogenic...
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Effects of an electric toothbrush combined with 3-color light-emitting diodes on antiplaque and bleeding control: a randomized controlled study

Kwon C, Lee JM, Suh JY, Seo SJ, Lee Y, Kim YG

Purpose: This randomized controlled study aimed to evaluate the effects of an electric toothbrush with 3 colors of light-emitting diodes (LEDs) on antiplaque and bleeding control. Methods: This randomized, placebo-controlled, double-blinded,...
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Korean clinical practice guidelines for preventing transmission of coronavirus disease 2019 (COVID-19) in hemodialysis facilities

Park HC, Kim DH, Yoo KD, Kim YG, Lee SH, Yoon HE, Kim DK, Kim SN, Kim MS, Jung YC, Kim YS, Lee YK, The Korean Society of Nephrology COVID-19 Task Force Team

Coronavirus disease 2019 (COVID-19) is a highly contagious viral disease that is caused by the novel virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). COVID-19 has become pandemic since December 2019,...
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