Korean J Pediatr.
2004 Oct;47(10):1106-1109.
A Case of Fulminant Hepatitis from Hepatitis A in a Child
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Eulji University, Korea.
- 2Department of Pediatrics, College of Medicine, Konkuk University, Korea. baedori@hanafos.com
- 3Department of Pathology, College of Medicine, Eulji University, Seoul, Korea.
Abstract
- Fulminant hepatitis from hepatitis A in children is rare and has a low survival rate. We report a case of fulminant hepatitis from hepatitis A in a 12-year-old girl. The patient was admitted because of a three day history of fever, epigastric pain and vomiting. On her second hospital day, she had insomnia, anxiety, dysthesia, continuous fever, vomiting and nausea. In laboratory findings, decreased white blood cell and platelet count, markedly elevated serum aminotransferase levels, elevated serum bilirubin levels, prolonged prothrombin time and partial thromboplastin time were seen. Factor VIII appeared normal range. The histopathologic findings were necrosis in hepatic lobules, periportal necrosis, portal lymphocytic infiltration and fibrous portal expansion. We treated the patient with supportive care. After treatment, clinical manifestations and laboratory findings were improved.
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