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Assay Sensitivity Difference Can Induce Anti-Hepatitis A Virus IgM Non-Reactive But Total (IgM and IgG) Reactive Results in Early Acute Hepatitis A

Kim SK, Yoo K, Huh J

Although anti-hepatitis A virus (HAV) IgM non-reactive and anti-HAV total (immunoglobulin [Ig] M and IgG) reactive results are generally interpreted as immunity to HAV, some early acute hepatitis A patients...
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Ten-Year Trends of Hepatitis A Seroprevalence in People Living with HIV in Korea

Lee S, Lee JE, Lee SO, Sim YK, Lee SH

Epidemiological information on hepatitis A among people living with HIV (PLHIV) in Korea is scarce. This retrospective study was performed at a tertiary care hospital and included 756 PLHIV with...
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Viral Hepatitis in Patients with Inflammatory Bowel Disease

Shin SH, Park SH

There has been a rise in the incidence of inflammatory bowel disease (IBD) in developing countries, including South Korea. Consequently, the use of immunosuppressive agents such as immunomodulators or biologics...
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Diagnostic Accuracy of Machine Learning Algorithms for Hepatitis A Antibody

Lim J

Purpose: The objective of this study was to develop a model for predicting the positivity of hepatitis A antibody based on nationwide health information using a machine learning technique. Methods: We...
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An outbreak of hepatitis A associated with salted clams in Busan, Korea

Son H, Lee M, Eun Y, Park W, Park K, Kwon S, Kim S, Kim C

OBJECTIVES: In July 2019, there were multiple reports on patients with hepatitis A among the visitors of a restaurant in Busan. The current study presents the results of an epidemiological...
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Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation

Chang Y, Kim C, Kim N, Kim JJ, Lee H

Objectives: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for...
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Epidemiological and Clinical History of Viral Hepatitis in Korea

Yoon JH, Cho SH, Kim DY, Yu SJ, Han KH

Viral hepatitis is the most important cause of acute and chronic liver disease in Korea. Particularly, hepatitis B virus (HBV) is the leading cause of liver-related mortality. Because of the nationwide...
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Report of the Korean Association of External Quality Assessment Service on Hepatitis Serology (2018–2019)

Cho EJ, Choi AR, Ryu JH, Yun SJ, Oh EJ

As a diagnostic immunology program of the Korean Association of External Quality Assessment Service, two trials were organized to assess the external quality of hepatitis serology in 2018 and 2019....
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Acute Pancreatitis associated with Acute Hepatitis A in an Old Aged Patient

Hong K, Paik CN, Jo IH, Kim DB

Acute pancreatitis caused by acute hepatitis A is extremely rare, with only a small number of cases in young adults having been reported. This paper presents a 74-year-old female patient...
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Recent Seroprevalence of Anti-hepatitis A IgG in the Korean Population: a Large, Population-based Study

Choi R, Park MJ, Lee SG, Lee EH

Background: Because there is limited recent information on this topic, this study investigated the seroprevalence of anti-hepatitis A virus (HAV) immunoglobulin G (IgG) in the South Korean population in 2015–2017. Methods:...
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A Study on Seroprevalence of Hepatitis A Virus among Healthcare Workers at a University-Affiliated Hospital in Deajeon, Korea

Ji SK, Jang SH, Park MH, Lee JE, Jeong HS, Park J, Han SB, Yi Y, Park SH

Background: In 2019, there was an outbreak of hepatitis A virus (HAV) infections in Korea. This study was performed to determine the seroprevalence of HAV among healthcare workers (HCWs) in...
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Autoimmune Hepatic Failure Following Acute Hepatitis A is Accompanied by Inflammatory Conversion of Regulatory T Cells

Leem G, Kim BK, Shin EC, Park JY

To evaluate the pathophysiology of autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who...
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Seropositive rate of the anti-hepatitis A immunoglobulin G antibody in maintenance hemodialysis subjects from two hospitals in Korea

Kim H, Ryu J, Lee YK, Choi MJ, Cho A, Koo JR, Baik SY, Lee EH, Yoon JW, Noh JW

BACKGROUND/AIMS: Hepatitis A virus (HAV) is a self-limiting infectious disease, but 1% of subjects develop fulminant hepatitis. The prevalence of the anti-HAV immunoglobulin G (IgG) antibody in hemodialysis subjects in...
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Perspectives on Acute Hepatitis A Control in Korea

Kang SH, Kim MY, Baik SK

Until 1995, the incidence of symptomatic acute hepatitis A was minimal and there were no cases of national outbreak in Korea. However, there was a nationwide outbreak of hepatitis A...
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Seroprevalence of Hepatitis A Virus in Pediatric Patients with Hematologic Malignancies after Chemotherapy and Hematopoietic Cell Transplantation

Moon JU, Han AL, Lee ES, Kim SK, Han SB, Lee JW, Chung NG, Cho B, Jeong DC, Kang JH

This retrospective study was performed to determine the seroprevalence of hepatitis A virus (HAV) in children and adolescents with hematologic malignancies after the completion of chemotherapy and hematopoietic cell transplantation...
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Hepatitis A Virus Infection from a Contaminated Tap of Ground Water Facility in a Neighborhood Park, Republic of Korea

Ryu S, Won SA, Uh J, Song JY

A patient with Hepatitis A virus (HAV) infection was notified to the public health authority. The identical HAV was found at a water dispensing outlet at the ground water facility...
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Causes and countermeasures for repeated outbreaks of hepatitis A among adults in Korea

Ki M, Son H, Choi BY

The 2019 hepatitis A outbreak has become increasingly prevalent among adults in Korea and is the largest outbreak since that in 2009–2010. The incidence in the current outbreak is highest...
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Report on the External Quality Assessment Scheme of Hepatitis Viral Markers in Korea, (2016–2017)

Cho EJ, Choi AR, Ryu JH, Yun SJ, Lee W, Chun S, Min WK, Oh EJ

As part of the immunoserology program of the Korean Association of External Quality Assessment Service, we organized two trials on the external quality assessment of hepatitis viral markers in 2016...
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A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection

Hong SE, Choo JW, Lim SK, Lee SJ, Park JW, Kim SE, Kim JH, Park CK

Concurrent presentation of acute hepatitis A virus (HAV) infection and Graves' disease has not been reported in literature worldwide. Although there is no well-established mechanism that explains the induction of...
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Current status and strategies for the control of viral hepatitis A in Korea

Yoon EL, Sinn DH, Lee HW, Kim JH

Hepatitis A virus is one of the most frequent causes of foodborne infection, which is closely associated with sanitary conditions and hygienic practices. The clinical spectrum of acute hepatitis A...
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