Korean J Prev Med.  2001 Nov;34(4):323-330.

Cohort Study on Age at Menopause and Mortality- Kangwha Cohort Study -

• Hong JS
• Yi SW
• Jee SH
• Sohn TY
• Ohrr H

Abstract

OBJECTIVE
To examine the association between age at menopause and mortality in a population-based sample of women in Kangwha, Korea.
METHODS
From the Kangwha Cohort, followed-up from 1985 to 1999, the data of the over 55 year old female group(n=3,596) was used in this study to examine the association between age at menopause and mortality. We calculated the all causes mortality risk ratio and the cancer mortality risk ratio by age at menopause grouping using the Cox Proportional Hazards Model with adjustments for age, BMI, smoking, education, chronic disease, self-rated health status, alcohol consumption and age at first birth. RESULT AND CONCLUSION: Compared to women who had menopause at 45-49 years, the all causes mortality risk ratio was 1.24 for women with menopause at less than 40 years(95% CI=1.01-1.53) and 1.05 for women with menopause at over 50 years(95% CI=0.92-1.20). Also, compared to women who had menopause at 45-49 years, the cancer mortality risk ratio was 1.53 for women with menopause at less than 40 years(95% CI=0.78-2.98) and 1.17 for women with menopause at over 50 years(95% CI=0.77-1.80).

Keyword

Menopause; Mortality; Cohort studies

MeSH Terms

Alcohol Drinking
Birth Order
Chronic Disease
Cohort Studies*
Education
Female
Humans
Korea
Menopause*
Middle Aged
Mortality
Odds Ratio
Proportional Hazards Models
Smoke
Smoking
Smoke