Evaluation of Yeong Dong Reagent for the Automated Chemistry Test

Lee, Seong Gyu; Kong, Sun Young; Song, Sun Mi; Lee, Su Youn; Kim, Jong Won

Abstract

BACKGROUND: Most clinical laboratories in the Korean have used the imported reagents for the automated chemistry test. But, considering with the cost-effectiveness of clinical laboratory, We should continuously develop and improve the domestic reagent. So we evaluated the domestic reagent, compared to the imported reagent for the automated chemistry test.
METHODS
The comparison of results between Yeong Dong reagent (Yeong Dong pharmaceutical Corp., Seoul, Korea) and the imported reagents such as DAICHI reagent (Daichi pure chemicals Corp., Tokyo, Japan) and Roche reagent (Roche Diagnostic System, Switzerland) for the automated chemistry analyzer, Hitachi 7070 (Hitachi, LTD., Tokyo, Japan), was attempted in the 9 items as follows; Total protein, albumin, blood urea nitrogen, creatinine, cholesterol, uric acid, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) according to NCCLS guidelines (EP5-A, EP6-P and EP-9-A). But we could not test interference.
RESULTS
Satisfactory results were obtained for within-run and total precision in most analytes, compared with the imported reagent. The linearity was acceptable for all analytes. Good correlation with the imported reagent was also demonstrated, but the proportional biases were found for some analytes such as albumin, ALP, uric acid and creatinine.
CONCLUSIONS
Yeong Dong reagent showed satisfactory precision, linearity, and good correlation with the imported reagents. We concluded that a reliable result could be resulted from Yeong Dong reagent for the automated chemistry analyzer.

Evaluation of Yeong Dong Reagent for the Automated Chemistry Test

Abstract

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