KoreaMed, a service of the Korean Association of Medical Journal Editors (KAMJE), provides access to articles published in Korean medical, dental, nursing, nutrition and veterinary journals. KoreaMed records include links to full-text content in Synapse and publisher web sites.
Cancer screening evaluation will be a important issue in Korea in near future. Bias in cancer screening evaluation is well known by concept, but it is not applied yet using...
Bias is the main problem that should be considered in epidemiologic research. Information bias caused by measurement error and confounding caused by total energy intake are listed as the main...
The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a...
The cohort study is an observational epidemiological study which selects the specific study population attempting to study the relatiqnship between an exposure to the purported cause and the subsequent risk...
There are many epidemiologic studies to find the relationship between disease occurrence and categorized exposure variables which are measured in continuous scales. Recently, it has been found that the differential...
The development of microarray technology has facilitated the understanding of gene expression profiles. Despite its convenience, the cause of dye-bias that confounds data interpretation in dual-color DNA microarray experiments is...
Propensity score matching method (PSM) is widely used in observational study to reduce selection bias. Observational study lacks randomization, hence, statistical inferences without bias adjustments usually include observed or unobserved...
PURPOSE: Among the numerous clinical researches and following articles, there are few cases that apply proper methodology, which guarantees high reliability. By understanding the right concept and randomization of proper...
Evaluation of scientific evidence in the medical literature is based on the research methodology, which can be the fundamental tool for medical professionals to improve their practice. Since analytic studies...
Randomized controlled trials (RCTs) are accepted as the "gold standard" for providing the best evidence for research. However, their application in clinical practice or health policy is limited by ethical...
A case-crossover study design is a method to assess the effect of transient exposures on the risk of onset of acute events. Which was introduced by Maclure in 1991 for...
The proportion of cancer related mortality is 26.3% in 2004 and it is still increasing. The most common cancers are stomach cancer, lung cancer, liver cancer, colon cancer, breast cancer,...
Meta-analysis is a statistical tool for combining the results of different studies on the same topic, providing a precise estimate of the effect size and increasing statistical strength, which is...
Randomized controlled trial is widely accepted as the best design for evaluating the efficacy of a new treatment because of the advantages of randomization (random allocation). Randomization eliminates accidental bias,...
The use of meta-analysis (MA), which is placed on top of the evidence hierarchy, in studies has been increasing exponentially. MA has three effect size families. Using the category of...