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The Uric Acid and Gout have No Direct Causality With Osteoarthritis: A Mendelian Randomization Study

Lee YH, Song GG

OBJECTIVE: To examine whether uric acid level or gout is causally associated with the risk of osteoarthritis. METHODS: We performed a two-sample Mendelian randomization (MR) analysis using inverse-variance weighted (IVW), MR-Egger...
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Vitamin D and Male Fertility: An Updated Review

Cito G, Cocci A, Micelli E, Gabutti A, Russo GI, Coccia ME, Franco G, Serni S, Carini M, Natali A

To date, the key role of vitamin D in male reproductive system has been suggested, since the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the testis...
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Cardiac CT for Measurement of Right Ventricular Volume and Function in Comparison with Cardiac MRI: A Meta-Analysis

Kim JY, Suh YJ, Han K, Kim YJ, Choi BW

OBJECTIVE: We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional...
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External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Ji SH, Lee JH, Cho JY, Kim HS, Jang YE, Kim EH, Kim JT, Kim HS

BACKGROUND: Previously, a linked pharmacokinetic-pharmacodynamic model (the Kim model) of propofol with concurrent infusion of remifentanil was developed for children aged 2–12 years. There are few options for pharmacokinetic-pharmacodynamic model...
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Determination of maternal risk factors of preterm delivery: adjusted for sparse data bias; results from a population-based case-control study in Iran

Valipour M, Ayubi E, Shiravand , Moradi Y, Abbaszadeh A, Amrai F, Mokhtari S, Bahmanpour K, Mansori K

OBJECTIVE: To determine the maternal risk factors associated with preterm delivery in Iran. METHODS: A population-based case-control study was conducted including 48 women having preterm delivery (case group) and 100 women...
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Timing of Hip-fracture Surgery in Elderly Patients: Literature Review and Recommendations

Seong YJ, Shin WC, Moon NH, Suh KT

The incidence of hip fractures is rapidly increasing with an aging population and is now one of the most important health concerns worldwide due to a high mortality rate. The...
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Diagnostic Accuracy of a Novel On-site Virtual Fractional Flow Reserve Parallel Computing System

Park HB, Jang Y, Arsanjani , Nguyen MT, Lee SE, Jeon B, Jung S, Hong Y, Ha S, Kim S, Lee SW, Chang HJ

PURPOSE: To evaluate the diagnostic accuracy of a novel on-site virtual fractional flow reserve (vFFR) derived from coronary computed tomography angiography (CTA). MATERIALS AND METHODS: We analyzed 100 vessels from 57...
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Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses

Spiller W, Jung KJ, Lee JY, Jee SH

Cardiovascular disease (CVD) is considered a primary driver of global mortality and is estimated to be responsible for approximately 17.9 million deaths annually. Consequently, a substantial body of research related...
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Incidence of Hypotension after Discontinuation of Norepinephrine or Arginine Vasopressin in Patients with Septic Shock: a Systematic Review and Meta-Analysis

Song JU, Lee J, Park HK, Suh GY, Jeon K

BACKGROUND: There has been no consensus regarding the discontinuation order of vasopressors in patients recovering from septic shock treated with concomitant norepinephrine (NE) and arginine vasopressin (AVP). The aim of...
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Phytopythium and Pythium Species (Oomycota) Isolated from Freshwater Environments of Korea

Nam B, Choi YJ

Oomycetes are widely distributed in various environments, including desert and polar regions. Depending upon different habits and hosts, they have evolved with both saprophytic and pathogenic nutritional modes. Freshwater ecosystem...
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Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA Sequencing

Kim JH, Kim J, Koo BS, Oh H, Hong JJ, Hwang ES

Zika virus (ZIKV) is one of the pathogens which is transmitted world widely, but there are no effective drugs and vaccines. Whole genome sequencing (WGS) of viruses could be applied...
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Phenotypes of allergic diseases in children and their application in clinical situations

Lee E, Hong SJ

Allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, are common heterogeneous diseases that encompass diverse phenotypes and different pathogeneses. Phenotype studies of allergic diseases can facilitate the identification of...
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Report of Korean Association of External Quality Assessment Service on the Accuracy-Based Lipid Proficiency Testing (2016–2018)

Kim JH, Cho Y, Lee SG, Yun YM

The accuracy-based lipid (ABL) proficiency testing (PT) program was started in 2016 by the Korean External Quality Assessment Service to minimize the matrix effect. We analyzed 3 years of the...
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Association Between Dental Implants and Cognitive Function in Community-dwelling Older Adults in Korea

Ki S, Yun J, Kim J, Lee Y

OBJECTIVES: This study aimed to evaluate the association between dental implants and cognitive function in community-dwelling older adults. METHODS: Data were collected from the baseline survey (2016–2017) of the Korean Frailty...
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A Systematic Review of Breast Care for Postpartum Mothers

Song JA, Hur MH

PURPOSE: The purpose of this study was to identify nursing interventions for the postpartum breast care of mothers and determine the effectiveness of interventions for breast pain and engorgement by...
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Effectiveness of Acceptance and Commitment Therapy for Chronic Pain Patients: A Systematic Review and Meta-Analysis

Kang HS, Hwang SD, Jun SE

PURPOSE: The aims of this study was to evaluate the effects of acceptance and commitment therapy (ACT) for chronic pain patients. METHODS: Based on the guidelines of the Preferred Reporting Items...
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Mendelian Randomization Analysis in Observational Epidemiology

Lee K, Lim CY

Mendelian randomization (MR) in epidemiology is the use of genetic variants as instrumental variables (IVs) in non-experimental design to make causality of a modifiable exposure on an outcome or disease....
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The Usefulness of a Wearable Device in Daily Physical Activity Monitoring for the Hospitalized Patients Undergoing Lumbar Surgery

Kim DH, Nam KH, Choi BK, Han IH, Jeon TJ, Park SY

OBJECTIVE: Functional outcomes have traditionally been evaluated and compared using subjective surveys, such as visual analog scores (VAS), the Oswestry disability index (ODI), and Short Form-36 (SF-36), to assess symptoms...
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Investigating possible causes of bias in a progress test translation: an one-edged sword

Cecilio-Fernandes D, Bremers A, Collares C, Nieuwland , van der Vleuten C, Tio RA

PURPOSE: Assessment in different languages should measure the same construct. However, item characteristics, such as item flaws and content, may favor one test-taker group over another. This is known as...
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Acupuncture for Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis

Lai BY, Cao HJ, Yang GY, Jia LY, Grant S, Fei YT, Wong E, Li XL, Yang XY, Liu JP

PURPOSE: To assess the effectiveness and safety of acupuncture for erectile dysfunction (ED). MATERIALS AND METHODS: We searched six major English and Chinese databases included randomized controlled trials (RCTs) testing acupuncture...
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