J Korean Surg Soc.  2003 Mar;64(3):269-274.

Acute Arterial Occlusion Associated with Protein C and S Deficiencies

  • 1Department of Surgery, University of Ulsan College of Medicine, Seoul Asan Hospital, Seoul, Korea.
  • 2Department of Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. ypcho@knh.co.kr


Sudden acute arterial occlusion can result from a multitude of pathological processes. Although the appearance and the secondary effects of an acute arterial occlusion are similar regardless of the underlying cause, the treatment and prognosis are different. Therefore, establishing a correct diagnosis is crucial. Acute arterial occlusion is most frequently a complication of ischemic cardiac disease, with an atrial fibrillation occurring in most patients. An identifiable noncardiac source of the acute arterial occlusion can be found in 5~10% of patients. Howerver, in these cases, the specific source of the occlusion cannot be determined clinically or even at autopsy. Possible hypercoagulable states should be suspected and appropriately evaluated, particularly in patients with no history of antecedent occlusive disease who present with sudden arterial occlusions, or in patients with malignant disease. Protein C and protein S deficiencies are frequently described as a cause of the hypercoagulable states. We reported 3 cases of acute arterial occlusion associated with protein C and S deficiencies.


Acute disease; Arterial occlusion; Protein C; Protein S; Deficiency

MeSH Terms

Acute Disease
Atrial Fibrillation
Heart Diseases
Pathologic Processes
Protein C*
Protein S
Protein S Deficiency
Protein C
Protein S
Full Text Links
  • JKSS
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr