J Korean Soc Radiol.  2013 Jul;69(1):53-56. 10.3348/jksr.2013.69.1.53.

A Case of Immunoglobulin G4-Related Sclerosing Disease Mimicking Lung Cancer

Affiliations
  • 1Department of Radiology, Seoul Medical Center, Seoul, Korea. ykradio@medimail.co.kr
  • 2Department of Pathology, Seoul Medical Center, Seoul, Korea.

Abstract

Immunoglobulin (Ig) G4-related sclerosing disease is a recently described systemic fibro-inflammatory disease associated with an elevated circulating level of IgG4 and extensive IgG4-positive lymphoplasmacytic infiltration, resulting in sclerosing inflammation involving various body organs. We experienced one case where surgery confirmed IgG4-related sclerosing disease as a solitary lung mass mimicking lung cancer. We report radiologic findings including chest computed tomography and positron emission tomography computed tomography, with clinical manifestations of IgG4-related sclerosing disease.

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