J Korean Pediatr Soc.  1981 Jul;24(7):652-658.

Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis

• Kim PK
• Kim KS
• Lee C
• Kim NA
• Lee JS

Abstract

Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations were normal limit in minimal lesion nephrotic syndrome. In one-forth of acute poststreptococcal glomerulonephritis and one-half of Henoch-Sch?lein purpura nephritis, serum IgA concentrations were elevated. 3) Serum IgM concentrations were normal in acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. We concluded that serum immunoglobulin concentrations were not useful as an aid in diagnosing glomerulonephritis.

Keyword

Glomerulonephritis; Acute poststreptococcal glomerulonephritis; Minimal lesion nephrotic syndrome; Henoch-Schonlein purpura nephritis

MeSH Terms

Glomerulonephritis*
Humans
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Immunoglobulins*
Nephritis
Nephrotic Syndrome
Purpura
Reference Values
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Immunoglobulins