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Porcine epidemic diarrhea virus: an update overview of virus epidemiology, vaccines, and control strategies in South Korea

Jang G, Lee D, Shin S, Lim J, Won H, Eo Y, Kim CH, Lee C

Porcine epidemic diarrhea virus (PEDV) has posed significant financial threats to the domestic pig industry over the last three decades in South Korea. PEDV infection will mostly result in endemic...
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Safely navigating kidney transplantation during the COVID-19 pandemic: the Singapore General Hospital’s experience

Tien CSY, Liew IT, Ho QY, Thangaraju S, Abdul Rahman MB, Lee C, Xin Hui Leah NC, He X, Siew LT, Shern Kee TY

Background: The coronavirus disease 2019 (COVID-19) pandemic curtailed transplant activities worldwide, driven by concerns about increased COVID-19-related mortality among kidney transplant recipients (KTRs), infections originating from donors, and decreased availability...
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Anatomy Versus Physiology: Is Breast Lymphatic Drainage to the Internal Thoracic (Internal Mammary) Lymphatic System Clinically Relevant?

Machado P, Liu JB, Needleman L, Lee C, Forsberg F

Approximately 15%−25% of breast lymphatic drainage passes through the internal thoracic (internal mammary) lymphatic system, draining the inner quadrants of the breast. This study aimed to use lymphosonography to identify...
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Submental intubation using laparoscopic trocar in zygomaticomaxillary complex fracture surgery in Korea: a case report

Do H, Lee C, Hong HD, Hong H, Lim HK, Kim S

Submental intubation is an effective alternative technique for airway management in patients with maxillofacial trauma. Compared with tracheostomy, it is less invasive, but has risks associated with potential airway compromise...
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Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases

Kong BS, Lee C, Cho YM

Mitochondria are complex metabolic organelles with manifold pathophysiological implications in diabetes. Currently published mitochondrial-encoded peptides, which are expressed from the mitochondrial open reading frame of the 12S ribosomal RNA type-c...
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Chronic Reserpine Administration for Depression Modeling in Zebrafish

Kim S, Han C, Ko YH, Kim YK, Yoon HK, Lee J, Kim S, Lee C, Shin C

Objectives This study aims to develop valid experimental models for depression through chronic reserpine exposure to zebrafish (Danio rerio). Methods The effect of chronic reserpine on zebrafish behavior in the novel tank was...
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Validation and Clinical Application of ONCOaccuPanel for Targeted Next-Generation Sequencing of Solid Tumors

Kim M, Lee C, Hong J, Kim J, Jeong JY, Park NJY, Kim JE, Park JY

Purpose Targeted next-generation sequencing (NGS) is widely used for simultaneously detecting clinically informative genetic alterations in a single assay. Its application in clinical settings requires the validation of NGS gene...
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Recent Trends in Real-World Data Access, Linkage and Validation of the United States, Europe, and South Korea and Further Recommendations for South Korea

Jeon M, Ha M, Lee C, Kim S, Oh I, Sung H, Shin JY

21st Century Cures Act of 2016 sparked interest in real-world data (RWD) and real-world evidence (RWE) worldwide. South Korea published several RWD/RWE guidelines as well as the United States and...
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A Novel Magnetic Resonance Quality Assurance Phantom (KMRP-4): Multi-Site Comparison With the American College of Radiology Phantom

Kumar S, Kim JM, Cha JG, Hwang JY, Jung SE, Lee C, Oh CH

Purpose: To propose a novel standard magnetic resonance imaging (MRI) phantom, hereafter called the Korea Magnetic Resonance Phantom-4th edition (KMRP-4). Its related quality control (QC) assessment protocols and its comparison...
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Childhood Sexual Abuse and Cortical Thinning in Adults With Major Depressive Disorder

Kim J, Lee C, Kang Y, Kang W, Kim A, Tae WS, Ham BJ, Chang J, Han KM

Objective A growing body of evidence reports on the effect of different types of childhood abuse on the structural and functional architecture of the brain. In the present study, we...
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Relationship between Anemia with Frailty and Nutritional Intake in Persons Age 65 and Older: The 2016–2018 Korea National Health and Nutrition Examination Survey

Jeong H, Lee C, Han SY, Ko YJ, Kim KJ

Background: Anemia is common in older people. Frailty scores can be used to predict the risk of anemia in addition to aging. This study aimed to investigate the association between...
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4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism

Ortiz DMD, Kim M, Lee HJ, Botanas CJ, Perez Custodio RJ, Sayson LV, Campomayor NB, Lee C, Lee YS, Cheong JH, Kim HJ

Major depressive disorder is a leading cause of disability in more than 280 million people worldwide. Monoamine-based antidepressants are currently used to treat depression, but delays in treatment effects and...
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Correction: Relative bradycardia in patients with COVID‑19

Jung L, Kim J, Ryu S, Lee C

Introduction Relative bradycardia (RB) is a relatively low heart rate response to rise in body temperature that occurs in several infectious diseases and can be an important clinical sign. In...
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Microbial Components and Effector Molecules in T Helper Cell Differentiation and Function

Lee C, Lee H, Park JC, Im SH

The mammalian intestines harbor trillions of commensal microorganisms composed of thousands of species that are collectively called gut microbiota. Among the microbiota, bacteria are the predominant microorganism, with viruses, protozoa,...
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Canine as a Comparative and Translational Model for Human Mammary Tumor

Kwon JY, Moskwa N, Kang W, Fan TM, Lee C

Despite the advances in research and treatment of human breast cancer, its incidence rate continues to increase by 0.5% per year, and the discovery of novel therapeutic strategies for specific...
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Sex Differences in COVID-19 Infection Fear in a Community Sample of Korean Adults Using Quantile Regression

Na H, Jung YE, Park C, Lee C, Kim MD, Bahk WM

This study aims to explore the impact of distributional changes in coronavirus disease 2019 (COVID-19) infection fear with sex differences. A quota sampling strategy was followed and 483 Korean adults...
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Combined Endoscopic Third Ventriculostomy and Lumboperitoneal Shunt Surgery in an Elderly Patient With Complex Hydrocephalus: Mixture of Late-onset Obstructive and Communicating Hydrocephaluses

Yoon SY, Kang K, Lee C, Hwang JH, Hahm MH, Park E, Park KS

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Measurement of S1 foramen depth for ultrasound-guided S1 transforaminal epidural injection

Kim YS, Park S, Lee C, Lee SK, Doo AR, Son JS

Background: Ultrasound-guided first sacral transforaminal epidural steroid injection (S1 TFESI) is a useful and easily applicable alternative to fluoroscopy or computed tomography (CT) in lumbosacral radiculopathy. When a needle approach...
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A retrospective study of new patients who visited Wonkwang University Dental Hospital and Pediatric Dentistry for the past 5 years and performed pulpectomy

Lee C, Ra J

Objectives: This study was conducted to investigate the correlation between the individual characteristics of the children and the teeth that had performed pulpectomy for children who visited Wonkwang University Dental...
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A Case of Bilateral Sudden Sensorineural Hearing Loss Accompanying Unilateral Acute Otitis Media as a First Presentation of Human Immunodeficiency Virus Infection

Lee C, Yeo CD, Lee EJ

The etiologies of sudden sensorineural hearing loss (SSNHL) include idiopathic, viral infections, vascular occlusion, abnormal cellular stress responses within the cochlea, and a variety of immune-mediated mechanisms. Although idiopathic cause...
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