Korean J Obstet Gynecol.  2011 Oct;54(10):639-642. 10.5468/KJOG.2011.54.10.639.

Gastrointestinal stromal tumor in vagina: A case report

• Ha SY
• Lee KB
• Lee SP

• KMID: 1836753
• DOI: http://doi.org/10.5468/KJOG.2011.54.10.639

Abstract

Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that usually arises within the gastrointestinal tract. However extragastrointestinal stromal tumor (EGIST) is a rare tumor (5%), especially few cases of EGIST arising in vagina have currently been reported in the literature. We have experienced a case of vaginal GIST. A 49-year-old female presented with vaginal mass for three weeks. The mass was located posterolateral vagina near to introitus and 3.0 x 2.5 cm in size. Histological examination showed hypercelluar spindle cell proliferation and more than 10 mitoses per 50 high power fields. They were positive for c-kit (CD 117) and CD34. Surgery is the most effective treatment and long term follow up is warranted.

Keyword

Gastrointestinal stromal tumor; Vagina

MeSH Terms

Cell Proliferation
Female
Follow-Up Studies
Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Humans
Middle Aged
Mitosis
Vagina

Figure

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  Fig. 1 Transvaginal ultrasonography shows a 3.0 × 2.5 cm sized solid mass in the posterolateral vagina with increased vascularity.

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  Fig. 2 There are bundles of hypercellular spindle cells with frequent mitosis (A: H&E, ×200). The tumor cells are positive for c-kit (B: c-kit, ×200) and CD34 (C: CD34, ×200).

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