Korean J Med.  2011 Jun;80(Suppl 2):S295-S300.

A Case of an Extragastrointestinal Stromal Tumor of the Pelvic Cavity Presenting with Hematuria

Affiliations
  • 1Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. lhggi@paik.ac.kr
  • 2Department of Pathology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Abstract

Although gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, it also occurs in the non-gastrointestinal tract, and is referred to as extragastrointestinal stromal tumor (EGIST). In this report, we describe a 48-year-old female patient who presented with hematuria, and who was finally diagnosed with a primary extragastrointestinal stromal tumor of the pelvic cavity involving the bladder, vagina and left ureter. Tumor cells were positive for immunohistochemical staining for CD117 antigen (proto-oncogene protein c-kit), CD34, and vimentin, whereas they were negative for desmin, smooth muscle actin, and S-100 protein. These findings provide histopathological and immunohistochemical evidence for diagnosing this tumor as EGIST.

Keyword

Gastrointestinal stromal tumor; Proto-oncogene protein c-kit; Pelvic cavity

MeSH Terms

Actins
Desmin
Female
Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Hematuria
Humans
Middle Aged
Muscle, Smooth
Proto-Oncogene Proteins c-kit
S100 Proteins
Ureter
Urinary Bladder
Vagina
Vimentin
Actins
Desmin
Proto-Oncogene Proteins c-kit
S100 Proteins
Vimentin
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