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Bismuth-Based Quadruple Therapy versus MetronidazoleIntensified Triple Therapy as a First-Line Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial

Seo SI, Lim H, Bang CS, Yang YJ, Baik GH, Lee SP, Jang HJ, Kae SH, Kim J, Kim HY, Shin WG

Background/Aims: Clarithromycin resistance is a main factor for treatment failure in the context of Helicobacter pylori infection. However, the treatment regimen for clarithromycin-resistant H. pylori infection has not yet been determined....
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Body Mass Index, Muscle Mass, and All-Cause Mortality in Patients With Acute Heart Failure: The Obesity Paradox Revisited

Hwang IC, Choi HM, Yoon YE, Park JJ, Park JB, Park JH, Lee SP, Kim HK, Kim YJ, Cho GY

Background and Objectives: Lower body mass index (BMI) is considered a poor prognostic factor in patients with heart failure (HF). We aimed to investigate the clinical impact of BMI on...
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Venous Thromboembolism in Heart Failure Patients: Building Evidence towards Better Care and the Need for Precision

Lee SP

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The Korean Hypertension Cohort study: design and baseline characteristics

Lee HY, Lee JY, Shin HG, Cho SH, Park KI, Oh GC, Lee SP, Kim H, Lee HS, Kim KI, Kang SH, Lee JH, Jang SY, Lee JH, Kim KH, Cho JY, Park JH, Jang J, Park SK, Bak JK

Background/Aims: Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients. Methods:...
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Measurement of Fractional Exhaled Nitric Oxide in Adults: Comparison of Two Different Analyzers (NIOX VERO and NObreath)

Kang SY, Lee SM, Lee SP

Background: Fractional exhaled nitric oxide (FeNO) is a non-invasive marker for eosinophilic airway inflammation and a good predictor of response to corticosteroids. There is a need for a reliable and...
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Atorvastatin Induces FXR and CYP7A1 Activation as a Result of the Sequential Action of PPARγ/PGC-1α/HNF-4α in Hep3B Cells

Lee J, Hong EM, Jung JH, Park SW, Lee SP, Koh DH, Jang HJ, Kae SH

Background/Aims: PPARγ, farnesoid X receptor (FXR) and CYP7A1 are associated with solubility of bile. This study was performed to understand a mechanism and interactions of statin-induced PPARγ, PGC-1α and HNF-4α...
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Progression of ascending aortopathy may not occur after transcatheter aortic valve replacement in severe bicuspid aortic stenosis

Jung JH, Kim HK, Park JB, Lee SP, Koo BK, Kim YJ, Kim HS, Sohn DW

Background/Aims: We evaluated changes in the ascending aorta dimension post-transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve (BiAV) and tricuspid aortic valve (TAV) patients. Methods: Patients with severe aortic stenosis...
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Allergen-Specific Immunotherapy Against Allergic Respiratory Diseases

Kang SY, Yang MS, Lee SM, Lee SP

Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It is widely held that the efficacy of a given therapeutic modality should be proven by well-designed double-blind...
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Early Surgery versus Watchful Waiting in Patients with Moderate Aortic Stenosis and Left Ventricular Systolic Dysfunction

Moon I, Kim M, Choi JW, Park JB, Hwang HY, Kim HK, Kim YJ, Kim KH, Kim KB, Sohn DW, Lee SP

Background and Objectives: Severe aortic stenosis (AS) with left ventricular systolic dysfunction (LVSD) is a class I indication for aortic valve replacement (AVR) but this recommendation is not well established...
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Intralymphatic allergen-specific immunotherapy

Kang SY, Jung JH, Lee SM, Lee SP

Although allergen-specific immunotherapy (AIT) is a standard treatment for allergic diseases, only 5% or less of patients in whom AIT is indicated have been receiving immunotherapy because AIT needs a...
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Middle meningeal artery embolizationto treat progressive epidural hematoma:a case report

Park TJ, Lee SP, Baek J, Ryou K, Kim SH

Progressive epidural hematoma is a form of acute epidural hematoma that gradually expands from a small initial hematoma; in cases that are clinically aggravated due to the presence of a mental illness...
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Cardiac Magnetic Resonance Feature Tracking in Aortic Stenosis: Exploration of Strain Parameters and Prognostic Value in Asymptomatic Patients with Preserved Ejection Fraction

Kim MY, Park EA, Lee W, Lee SP

OBJECTIVE: To determine the most valuable cardiac magnetic resonance feature tracking (CMR-FT) parameters for evaluating aortic stenosis (AS) and determine whether they can predict the prognosis in asymptomatic AS patients...
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Usefulness of Carbohydrate Antigen 19-9 Test in Healthy People and Necessity of Medical Follow-up in Individuals with Elevated Carbohydrate Antigen 19-9 Level

Lee SP, Sung IK, Kim JH, Lee SY, Park HS, Shim CS

BACKGROUND: Carbohydrate antigen 19-9 (CA 19-9) is a tumor marker whose level is elevated in many types of cancers and other benign conditions. CA 19-9 levels are frequently found to...
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ABC Classification Is Less Useful for Older Koreans Born before 1960

Kwon H, Lee SY, Kim JH, Lee SP, Kim JH, Sung IK, Park HS, Shim CS

BACKGROUND/AIMS: In the ABC classification system, group A consists of seronegative subjects without gastric corpus atrophy. This study aimed to determine the prevalence and characteristics of pseudo group A subjects. METHODS:...
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Fabry Disease that Phenocopies Hypertrophic Cardiomyopathy: a thorough Genetic ‘Detective’ Identifies the ‘Rogue’ Hidden in the GLA Gene

Kwon S, Lee SP, Park SS, Kim BJ, Kim HK, Cho HJ, Seong MW, Sohn DW

No abstract available.
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Coronary Computed Tomography Angiography for the Diagnosis of Vasospastic Angina: Comparison with Invasive Coronary Angiography and Ergonovine Provocation Test

Park J, Kim HK, Park EA, Park JB, Lee SP, Lee W, Kim YJ, Sohn DW

OBJECTIVE: To investigate the diagnostic validity of coronary computed tomography angiography (cCTA) in vasospastic angina (VA) and factors associated with discrepant results between invasive coronary angiography with the ergonovine provocation...
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Understanding the Natural History of Bicuspid Aortic Valve: Are We Close to Understanding It?

Lee SP

No abstract available.
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Study Design for the 2016 Baseline Survey of a Health System Strengthening Project in Quoc Oai District, Hanoi, Vietnam

Hoang VM, Oh J, Nguyen BN, Dat LM, Lee JK, Tran TG, Nguyen VH, Lee SP, Bang KS, Cho Y, Kim SY, Lee HY, Le QC, Choi N, Dinh TS, Luu NH

BACKGROUND: In order to provide essential scientific evidence on the population's health status and social health determinants as well as the current capacity of the health care system in Vietnam...
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Contemporary Imaging Diagnosis of Cardiac Amyloidosis

Lee SP, Park JB, Kim HK, Kim YJ, Grogan M, Sohn DW

Cardiac amyloidosis is a rare disease that frequently presents as ventricular hypertrophy. However, diagnosis is not always easy or straightforward as there are several myocardial disorders that phenocopy cardiac amyloidosis....
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Questionnaire survey for the clinical trial participants who experienced both digital and conventional impression

Yang E, Kim B, Lee JJ, Lee SP, Lim YJ

PURPOSE: The aim of this study was to assess the patients' perception, acceptance, and preference of the difference between a conventional impression and digital impression through questionnaire survey. MATERIALS AND METHODS:...
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