Korean J Gastroenterol.  2013 Oct;62(4):206-212. 10.4166/kjg.2013.62.4.206.

Is There a Difference in the Prevalence of Gastroesophageal Reflux Disease between Peritoneal Dialysis and Hemodialysis Patients?

Affiliations
  • 1Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. ismkim@kyuh.ac.kr

Abstract

BACKGROUND/AIMS
Gastroesophageal reflux disease (GERD) is a common upper gastrointestinal disorder in patients with chronic kidney disease (CKD). However, little is known about the prevalence of GERD in dialysis patients. The aim of the present study was to investigate the difference in the prevalence of GERD in peritoneal dialysis and hemodialysis patients.
METHODS
From July 2010 to August 2011, peritoneal dialysis patients (n=30) and hemodialysis patients (n=38) were enrolled. The prevalences of GERD were assessed at a single center with endoscopic findings and interviews using a questionnaire. Also, risk factors of GERD were evaluated.
RESULTS
The prevalences of GERD in peritoneal dialysis and hemodialysis patients were 33.3% and 39.5% (p=0.748), respectively. The prevalences of erosive reflux esophagitis (ERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 23.7% (p=0.477), respectively. The prevalences of nonerosive reflux disease (NERD) in peritoneal dialysis and hemodialysis patients were 16.7% and 13.2% (p=0.685), respectively. The prevalences of GERD, ERD and NERD were higher than those of the general population. The risk factor for GERD was age in hemodialysis patients.
CONCLUSIONS
The prevalence of GERD in dialysis patients was higher than that in the general population. However, there was no significant difference between peritoneal dialysis and hemodialysis patients.

Keyword

Gastro-esophageal reflux; Peritoneal dialysis; Renal dialysis; Chronic kidney failure

MeSH Terms

Aged
Body Mass Index
Diabetes Mellitus, Type 2/complications
Esophagitis, Peptic/complications/epidemiology
Female
Gastroesophageal Reflux/complications/*epidemiology
Gastroscopy
Helicobacter Infections/complications
Humans
Kidney Failure, Chronic/*complications
Male
Middle Aged
Peritoneal Dialysis/statistics & numerical data
Prevalence
Questionnaires
Renal Dialysis/statistics & numerical data
Risk Factors
Smoking

Figure

  • Fig. 1. Prevalences of gastroesophageal reflux disease (GERD), erosive reflux esophagitis (ERD) and nonerosive reflux disease (NERD). PD, peritoneal dialysis; HD, hemodialysis. The general population data from a nationwide multicenter prospective study in Korea abstracted from the article of Kim et al.8


Reference

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