Korean J Urol.  2009 Aug;50(8):757-761. 10.4111/kju.2009.50.8.757.

Efficacy and Safety of Intravenous Propofol Anesthesia during Transrectal Ultrasound-Guided Prostate Biopsy

• Cha KS
• Lee SW
• Cho JM
• Kang JY
• Yoo TK

• KMID: 1780478
• DOI: http://doi.org/10.4111/kju.2009.50.8.757

Abstract

PURPOSE
Transrectal ultrasonography (TRUS)-guided prostate biopsy causes fear and pain in 65% to 90% of patients. This study was designed to evaluated the use of intravenous propofol anesthesia during TRUS-guided prostate biopsy. MATERIALS AND METHODS: Between January 2006 and June 2008, 195 men undergoing a transrectal prostate biopsy were divided into 2 groups according to anesthetic technique. Group A consisted of 99 patients who received intravenous propofol infusion through an 18 gauge needle during TRUS-guided prostate biopsy. Group B consisted of 96 patients who intrarectally received 10 ml of 2% lidocaine gel 10 minutes before TRUS-guided prostate biopsy. Pain scores were assessed on a visual analogue scale immediately after prostate biopsy. RESULTS: The pain score was significantly reduced in group A compared with group B. There was a significant difference in the mean pain score between the 2 groups (1.0+/-1.3 in group A versus 2.9+/-2.0 in group B; p<0.01). Also, there was a significant difference in the willingness to undergo rebiopsy between the 2 groups (83.8% in group A versus 17.7% in group B; p<0.01). However, the complication rates were not significantly different between the 2 groups. Gross hematuria was found in 14% of group A patients and 18% of group B patients. CONCLUSIONS: Our results proved the advantage of intravenous propofol anesthesia during TRUS-guided prostate biopsy. Intravenous propofol infusion can be a safe and simple technique that significantly reduces pain during TRUS-guided prostate biopsy.

Keyword

Prostate; Biopsy; Pain; Propofol

MeSH Terms

Anesthesia
Biopsy
Hematuria
Humans
Imidazoles
Lidocaine
Male
Needles
Nitro Compounds
Propofol
Prostate
Imidazoles
Lidocaine
Nitro Compounds
Propofol

Figure

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  Fig. 1. Individual pain assessment by category. Group A: intravenous propofol, Group B: intrarectal lidocaine gel.

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