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Efficacy and safety of daclatasvir plus asunaprevir for Korean patients with HCV genotype Ib infection: a retrospective multi-institutional study

Cho BW, Kim SB, Song IH, Lee SH, Kim HS, Lee TH, Kang YW, Kim SH, Lee BS, Chae HB

BACKGROUND/AIMS: The combination of daclatasvir (DCV) and asunaprevir (ASV) has demonstrated a high sustained virologic response at 12 weeks (SVR12) and a low rate of adverse events in previous clinical...
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Efficacy and safety of daclatasvir and asunaprevir for hepatitis C virus genotype 1b infection

Nam HC, Lee HL, Yang H, Song MJ

BACKGROUND/AIMS: The treatment strategy for hepatitis C virus (HCV) has been changing rapidly since the introduction of direct-acting antivirals such as daclatasvir (DCV) and asunaprevir (ASV). We evaluated the efficacy...
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Tolfenamic Acid Inhibits the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma: Involvement of p38-Mediated Down-Regulation of Slug

Jittreetat T, Shin YS, Hwang HS, Lee BS, Kim YS, Sannikorn , Kim CH

PURPOSE: Tolfenamic acid (TA), a non-steroidal anti-inflammatory drug, is known to exhibit antitumor effects in various cancers apart from nasopharyngeal cancer (NPC). NPC exhibits high invasiveness, as well as metastatic...
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Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation

Kim MJ, Koo JE, Han GY, Kim B, Lee YS, Ahn C, Kim CW

Cancer stem cells (CSCs) have tumor initiation, self-renewal, metastasis and chemo-resistance properties in various tumors including colorectal cancer. Targeting of CSCs may be essential to prevent relapse of tumors after...
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Spontaneous Acetabular Periprosthetic Fracture in a Patient Continuously Having Zoledronic Acid

Tantavisut S, Tanavalee , Thanakit V, Ngarmukos , Wilairatana V, Wangroongsub Y

Zoledronic acid has been used for prevention of osteolytic and osteoblastic bone metastasis. This case report illustrates an undesirable consequence from prolonged usage of zoledronic acid in bone metastasis prevention....
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Risk Factors of Postoperative Pancreatic Fistula in Curative Gastric Cancer Surgery

Yu HW, Jung DH, Son SY, Lee CM, Lee JH, Ahn SH, Park DJ, Kim HH

  • KMID: 2372467
  • J Gastric Cancer.
  • 2013 Sep;13(3):179-184.
PURPOSE: Postoperative pancreatic fistula is a dreadful complication after gastric cancer surgery. The purpose of this study is to evaluate the actual incidence and risk factors of postoperative pancreatic fistula...
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Bowel Anastomosis in Single Port Laparoscopic Right Hemicolectomy: Comparison of Functional End to End Anastomosis and Isoperistaltic Side to Side Anastomosis

Yun SH, Chung SW, Yun JA, Park YA, Huh JW, Cho YB, Kim HC, Lee WY

  • KMID: 2325489
  • J Minim Invasive Surg.
  • 2013 Sep;16(3):45-51.
PURPOSE: Colorectal surgeries by single port laparoscopic surgery (SPLS) are increasing. While recent studies have reported results that are similar with the idea of conventional laparoscopy, SPLS is considered superior...
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Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay

Kim JW, Ahn I, Ryu SH, Jeon HR, Lee BS, Kim KB

  • KMID: 2317838
  • Toxicol Res.
  • 2013 Sep;29(3):217-219.
Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan cilexetil is a new antihypertensive drug associated with angiotensin II...
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Multi-Agent System as a New Approach to Effective Chronic Heart Failure Management: Key Considerations

Mohammadzadeh N, Safdari R, Rahimi A

OBJECTIVES: Given the importance of the follow-up of chronic heart failure (CHF) patients to reduce common causes of re-admission and deterioration of their status that lead to imposing spiritual and...
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Percutaneous Transhepatic Cholangioscopy: Does Its Role Still Exist?

Choi JH, Lee SK

  • KMID: 2165462
  • Clin Endosc.
  • 2013 Sep;46(5):529-536.
Percutaneous transhepatic cholangioscopy (PTCS) is the most widely used modality for diagnosis and treatment of biliary disease. Although many other novel technologies have been developed based on recent advances in...
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The Anatomy of the Superficial Temporal Artery in Adult Koreans Using 3-Dimensional Computed Tomographic Angiogram: Clinical Research

Kim BS, Jung YJ, Chang CH, Choi BY

OBJECTIVE: The increased use of bypass surgery in the treatment of ischemic cerebrovascular diseases requires a better understanding of the superficial temporal artery (STA) anatomy. This study is to describe...
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Perception of environment-friendly foods and satisfaction with school meals among students, their parents, and nutrition teachers at elementary schools in the Jindo area, Jeonnam

Jung MH, Chang MJ, Kim SH

  • KMID: 2327118
  • J Nutr Health.
  • 2013 Aug;46(4):369-381.
The aim of this study was to investigate the perception of students, their parents, and nutrition teachers regarding environment-friendly foods (EFF) and the satisfaction with school meals at elementary schools....
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Radicicol Inhibits iNOS Expression in Cytokine-Stimulated Pancreatic Beta Cells

Youn CK, Park SJ, Li MH, Lee MY, Lee KY, Cha MJ, Kim OH, You HJ, Chang IY, Yoon SP, Jeon YJ

Here, we show that radicicol, a fungal antibiotic, resulted in marked inhibition of inducible nitric oxide synthase (iNOS) transcription by the pancreatic beta cell line MIN6N8a in response to cytokine...
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Targeted Delivery of VP1 Antigen of Foot-and-mouth Disease Virus to M Cells Enhances the Antigen-specific Systemic and Mucosal Immune Response

Kim SH, Lee HY, Jang YS

Application of vaccine materials through oral mucosal route confers great economical advantage in animal farming industry due to much less vaccination cost compared with that of injection-based vaccination. In particular,...
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The effect of xylometazoline spray for expansion of nasal cavity

Han JS, Park SH, Shin YD, Kwon E, Shim WS, Bae JH

BACKGROUND: During nasotracheal intubation it is important to have proper pretreatment for nasal mucosa constriction and nasal cavity expanding. Nasal packing of epinephrine gauze is widely used as well as...
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Current Status and Future Perspectives on Minimally Invasive Esophagectomy

Kawakubo H, Takeuchi H, Kitagawa Y

  • KMID: 1967091
  • Korean J Thorac Cardiovasc Surg.
  • 2013 Aug;46(4):241-248.
Esophageal cancer has one of the highest malignant potentials of any type of tumor. The 3-field lymph node dissection is the standard procedure in Japan for surgically curable esophageal cancer...
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Indirect Radionuclide Coronary Angiography to Evaluate Gradients of Myocardial Blood Flow and Flow Reserve Through Coronary Stenosis Using N-13 Ammonia PET/CT

Kim HS, Cho SG, Kim JH, Bom HS

Although quantitative evaluation of myocardial blood flow (MBF) and myocardial flow reserve (MFR) has been perceived as an attractive advantage of positron emission tomography (PET) over other cardiac imaging technologies,...
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Keloids Treated with a Suction-Assisted Cartilage Shaver: A Report of Four Cases

Kim H, Hwang SH, Lee YS, Yoon SH, Seo JK, Sung HS

  • KMID: 1427414
  • Korean J Dermatol.
  • 2013 Aug;51(8):651-655.
Surgical excision of keloids is generally not accepted as a first treatment option, but many reports have described specialized surgical methods, such as intralesional and intramarginal excision. This operation preserves...
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Transient Distal Penile Corporoglanular Shunt as an Adjunct to Aspiration and Irrigation Procedures in the Treatment of Early Ischemic Priapism

Canguven O, Cetinel C, Horuz R, Tarhan F, Hamarat B, Goktas C

  • KMID: 2316018
  • Korean J Urol.
  • 2013 Jun;54(6):394-398.
PURPOSE: Ischemic priapism, a compartment syndrome, requires urgent treatment in order to nourish the corpora cavernosa. As the first step, aspiration of blood and irrigation of the cavernosal bodies is...
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The Effect of Curcumin on Breast Cancer Cells

Liu D, Chen Z

Curcumin, which is extracted from the plant Curcuma longa, has been used in the therapeutic arsenal for clinical oncology. Curcumin has chemopreventive and antitumoral activities against some aggressive and recurrent...
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