J Korean Med Sci.  2005 Jun;20(3):379-383. 10.3346/jkms.2005.20.3.379.

Relations of Plasma High-Sensitivity C-Reactive Protein to Various Cardiovascular Risk Factors

• Ryu SY
• Lee YS
• Park J
• Kang MG
• Kim KS

• KMID: 1778493
• DOI: http://doi.org/10.3346/jkms.2005.20.3.379

Abstract

This study was performed to evaluate the relation of high-sensitivity C-reactive protein (hsCRP) with several cardiovascular risk factors such as age, blood pressure, smoking habit and serum lipids, body mass index, blood glucose, regular exercise, alcohol drinking, white blood cell counts in a cross-sectional survey. Plasma hsCRP was measured by immunoturbidimetry in 202 subjects, aged over 50 yr, who participated in health-check survey in a rural area of Jeollanamdo, Korea. Plasma hsCRP level was 1.9 +/- 3.0 mg/dL. There were significant associations between hsCRP levels and age, white blood cell counts, blood glucose, diastolic blood pressure, HDL-cholesterol, body mass index and smoking status. In stepwise multivariate regression analysis, white blood cell counts, age, blood glucose, smoking status and body mass index were independent correlates of hsCRP levels. In conclusion, plasma hsCRP levels were associated with several cardiovascular risk factors, and these data are compatible with the hypothesis that CRP levels may be a marker for preclinical cardiovascular disease. Further what we need now are prospective studies to evaluate the association of C-reactive protein concentrations with subsequent cardiac events.

Keyword

C-Reactive Protein; Cardiovascular Abnormalities; Risk Factors; Cross-Sectional Studies

MeSH Terms

Alcohol Drinking
Blood Glucose/metabolism
Blood Pressure
Body Mass Index
C-Reactive Protein/*metabolism
Cardiovascular Diseases/*blood/physiopathology
Cross-Sectional Studies
Educational Status
Female
Humans
Male
Marital Status
Multivariate Analysis
Regression Analysis
Research Support, Non-U.S. Gov't
Risk Factors
Smoking
Socioeconomic Factors

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