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Regulatory T Cells - An Emerging Role in Transplantation

Feng G, Wood K

No abstract available.
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The Medical Science Research and Development Supported by the Korea Science and Engineering Foundation

Min TS, Han J, Kim SY, Rhee BD, Kim MS

This study examined ways of promoting research in the medical sciences by evaluating trends in research funding, and the present status of research funding by the Korea Science and Engineering...
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The Past, Present, and Future of Xenotransplantation

Ahn C, Kim JY, Lee BC, Kang SK, Lee JR, Hwang WS

No abstract available.
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In vivo characterization of the integrin beta3 as a receptor for Hantaan virus cellular entry

Song JW, Song KJ, Baek LJ, Frost B, Poncz M, Park KS

  • KMID: 755750
  • Exp Mol Med.
  • 2005 Apr;37(2):121-127.
Binding of viruses to cell surface molecules is an essential step in viral infection. In vitro studies suggested that the alpha v beta3 integrin receptor is the epithelial cell receptor...
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Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis

Jung HW, Choi SW, Choi JI, Kwon BS

  • KMID: 755660
  • Exp Mol Med.
  • 2004 Feb;36(1):13-22.
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose etiopathogenesis is not well understood. Although soluble (s) forms of 4-1BB (s4-1BB) and 4-1BB legand (s4-1BBL) have been detected in the...
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Association of the XRCC1 gene polymorphisms with cancer risk in Turkish breast cancer patients

Deligezer , Dalay N

  • KMID: 1103325
  • Exp Mol Med.
  • 2004 Dec;36(6):572-575.
The X-ray repair cross-complementing group 1 (XRCC1) gene is believed to play an important role in base excision repair and displays genetic polymorphisms. Data on the role of XRCC1 polymorphisms...
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Evidence that the fully assembled capsid of Leishmania RNA virus 1-4 possesses catalytically active endoribonuclease activity

Ro YT, Kim EJ, Lee HI, Saiz M, Jr RC, Patterson

  • KMID: 1380209
  • Exp Mol Med.
  • 2004 Apr;36(2):145-156.
In this study, Leishmania RNA virus 1-4 (LRV1-4) particles purified from host Leishmania guyanensis promastigotes were examined for capsid endoribonuclease. Temperature optimum for the endoribonulease activity was found to be...
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Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays

Yuk JS, Ha KS

  • KMID: 1033095
  • Exp Mol Med.
  • 2005 Feb;37(1):1-10.
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is...
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IgA Nephropathy in Renal Allografts-Recurrence and Graft Dysfunction

Jeong HJ, Huh KH, Kim YS, Kim SI

With time after transplantation, the recurrence of IgA nephropathy (IgAN) becomes a relevant cause of graft dysfunction and failure. However, only limited information has been published regarding the related clinical...
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Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells

Yoo SJ, Yoon BS, Kim JM, Song JM, Roh SI, You S, Yoon HS

  • KMID: 1089449
  • Exp Mol Med.
  • 2005 Oct;37(5):399-407.
Human embryonic stem cells (hESCs) need feeder cells for their maintenance in an undifferentiated state. In conventional culture systems, mouse embryonic fibroblasts (MEFs) serve as feeder cells to maintain hESCs....
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Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine

Jeon JH, Lee HJ, Jang GY, Kim CW, Shin DM, Cho SY, Yeo EJ, Park SC, Kim IG

  • KMID: 1103326
  • Exp Mol Med.
  • 2004 Dec;36(6):576-581.
The treatment of cystamine, a transglutaminase (TGase) inhibitor, has beneficial effects in several diseases including CAG-expansion disorders and cataract. We compared the inhibition characteristics of cystamine with those of cysteamine,...
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Endotoxin and House Dust Mite Allergen Levels on Synthetic and Buckwheat Pillows

Nam HS, Park CS, Crane J, Siebers R

Pillows are known to contain significant levels of indoor allergens and endotoxin, that are of importance to house dust mite sensitized asthmatics. Buckwheat pillows are commonly used in Korea. We...
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The Effects of Intradermal Vaccination with DNA Encoding for the T-cell Receptor on the Induction of Experimental Autoimmune Encephalomyelitis in B10.PL Mice

Kwon SS, Kim N, Yoo TJ

Intradermal gene administration was found to induce a more profound immune response than direct intramusclular gene injection. We performed intradermal vaccination of B10.PL mice with DNA encoding for the V...
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Sequence comparisons of 28S ribosomal DNA and mitochondrial cytochrome c oxidase subunit I of Metagonimus yokogawai, M. takahashii and M. miyatai

Lee SU, Huh S, Sohn WM, Chai JY

We compared the DNA sequences of the genus Metagonimus: M. yokogawai, M. takahashii, and M. miyatai. We obtained 28S D1 ribosomal DNA (rDNA) and mitochondrial cytochrome c oxidase subunit I...
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p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells

Park KS, Jeon SH, Oh JW, Choi KY

  • KMID: 1103323
  • Exp Mol Med.
  • 2004 Dec;36(6):557-562.
p21Cip/WAF1, an important regulator of cell proliferation, is induced by both p53- and extracellular signal regulated kinase (ERK) pathways. The induction of p21Cip/WAF1 occurs by prolonged activation of the ERKs...
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Mutations of the BRAF Gene in Papillary Thyroid Carcinoma in a Korean Population

Kim KH, Kang DW, Kim SH, Seong IO, Kang DY

The B-type Raf kinase (BRAF) protein is a serine/threonine kinase that has an important role in cellular proliferation, differentiation, and programmed cell death. The BRAF gene has been recently found...
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Imaging Findings of Hepatic Paragonimiasis: A Case Report

Kim EA, Juhng SK, Kim HW, Kim GD, Lee YW, Cho HJ, Won JJ

Hepatic paragonimiasis is a rare form of ectopic infestation caused by Paragonimus. We experienced a case of hepatic paragonimiasis that showed characteristic imaging findings. CT and MR images showed a...
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Common interleukin 10 polymorphism associated with decreased risk of tuberculosis

Shin HD, Park BL, Kim LH, Cheong HS, Lee IH, Park SK

  • KMID: 755751
  • Exp Mol Med.
  • 2005 Apr;37(2):128-132.
Interleukin 10 (IL10) is a powerful TH2-cell cytokine that inhibits lymphocyte replication and secretion of inflammatory cytokines. The genetic associations of polymorphisms in IL10 with clinical manifestations of tuberculosis (TB)...
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Immunization effect of recombinant P27/30 protein expressed in Escherichia coli against the hard tick Haemaphysalis longicornis (Acari: Ixodidae) in rabbits

You MJ

We investigated the induction of resistance to Haemaphysalis longicornis infestation in rabbits that had been immunized with recombinant H. longicornis P27/30 protein. The success of immunological control methods is dependent...
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Genetic and Environmental Influences on Birthweight in a Sample of Korean Twins

Hur YM

This study is the first report of genetic and environmental influences on birthweight using Korean twins. The sample consisted of 255 monozygotic (MZ) and 178 dizygotic (DZ) twin pairs drawn...
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