J Korean Soc Radiol.  2012 Mar;66(3):221-228. 10.3348/jksr.2012.66.3.221.

Variation of the Degree of Coronary Artery Stenosis during the Cardiac Cycle: Influence of Heart Rate or Calcium Score on Coronary CT Angiography

• Lee HK
• Jin GY
• Park JK
• Han YM
• Lee YS
• Kwon KS
• Kim SS

• KMID: 1439417
• DOI: http://doi.org/10.3348/jksr.2012.66.3.221

Abstract

PURPOSE
To assess the stenotic coronary artery diameter in systole and end-diastole by coronary CT angiography and to evaluate the change in diameter according to heart rate and calcium score.
MATERIALS AND METHODS
Twenty-seven patients with coronary artery stenosis that underwent a coronary CT angiography and invasive coronary angiography were enrolled in the study. We assessed the percentage of diameter change in the stenotic coronary artery between the systolic and end-diastolic phase and evaluated its relationship with heart rate or Agatston score using a linear regression analysis.
RESULTS
The mean difference in the change of vessel diameter was 12.9% for a heart rate of 50-59 beats/min (bpm), 11.3% for 60-69 bpm, 10% for 70-79 bpm, 20% for 80-89 bpm, 13% for 90-99 bpm, and 6.7% for 100-109 bpm, none of which were statistically significant (p = 0.760). For the Agatston score, the mean difference in the change of vessel diameter was 8.3% for a score < 100, 12.4% for 100-400, and 20% for > 400. The relationship between the change in diameter and Agatston score was statistically significant (p = 0.004).
CONCLUSION
The data suggest that a change in diameter of the stenotic coronary artery in systole and end-diastole might be affected by the Agatston score.

MeSH Terms

Angiography
Calcium
Coronary Angiography
Coronary Stenosis
Coronary Vessels
Glycosaminoglycans
Heart
Heart Rate
Humans
Linear Models
Mustard Compounds
Systole
Calcium
Glycosaminoglycans
Mustard Compounds

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