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Oral manifestation and root canal therapy of the patient with mucopolysaccharidosis

Yoon JH, Lee HI, Jang JH, Choi SH, Chang HS, Hwang YC, Hwang IN, Lee BN, Oh WM

Mucopolysaccharidosis (MPS) is an inherited metabolic disorder caused by a deficiency in enzymes that participate in the degradation of glycosaminoglycans (GAGs) such as heparin sulfate and dermatan sulfate. Left untreated,...
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Generation of novel hyaluronic acid biomaterials for study of pain in third molar intervention: a review

Shuborna N, Chaiyasamut T, Sakdajeyont W, Vorakulpipat C, Rojvanakarn M, Wongsirichat N

Hyaluronic acid (HA) has long been studied in diverse applications. It is a naturally occurring linear polysaccharide in a family of unbranched glycosaminoglycans, which consists of repeating di-saccharide units of...
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Nondestructive Assessment of Glycosaminoglycans in Engineered Cartilages Using Hexabrix-Enhanced Micro-Computed Tomography

Jin LH, Choi BH, Kim YJ, Oh HJ, Kim BJ, Yin XY, Min BH

It is very useful to evaluate the content and 3D distribution of extracellular matrix non-destructively in tissue engineering. This study evaluated the feasibility of using micro-computed tomography (µCT) with Hexabrix...
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Phytoestrogen (Daidzein) Promotes Chondrogenic Phenotype of Human Chondrocytes in 2D and 3D Culture Systems

Mahmod SA, Snigh S, Djordjevic I, Yee YM, Yusof R, Ramasamy T, Rothan HA

Clinical investigations have shown a significant relationship between osteoarthritis (OA) and estrogens levels in menopausalwomen. Therefore, treatment with exogenous estrogens has been shownto decrease the risk ofOA.However, the effect estrogen...
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Polycaprolactone Triol–Citrate Scaffolds Enriched with Human Platelet Releasates Promote Chondrogenic Phenotype and Cartilage Extracellular Matrix Formation

Rothan HA, Mahmod SA, Djordjevic I, Golpich M, Yusof R, Snigh S

In this paper we report the differentiating properties of platelet-rich plasma releasates (PRPr) on human chondrocytes within elastomeric polycaprolactone triol–citrate (PCLT–CA) porous scaffold. Human-derived chondrocyte cellular content of glycosaminoglycans (GAGs)...
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Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft

Maniatopoulou E, Bonovas S, Sitaras N

BACKGROUND: There is evidence that glycosaminoglycans (GAGs) are present in the hair shaft within the follicle but there are no studies regarding GAGs isolation and measurement in the human hair...
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Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR

Lee KY, Lee DH, Choi HC

BACKGROUND: Vascular smooth muscle cells (VSMC) proliferation contributes significantly to intimal thickening in atherosclerosis and restenosis diseases. Platelet derived growth factor (PDGF) has been implicated in VSMC proliferation though the...
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A superficial hyperechoic band in human articular cartilage on ultrasonography with histological correlation: preliminary observations

Han TS, Kwack KS, Park S, Min BH, Yoon SH, Lee HY, Lee KB

PURPOSE: To demonstrate the superficial hyperechoic band (SHEB) in articular cartilage by using ultrasonography (US) and to assess its correlation with histological images. METHODS: In total, 47 regions of interest (ROIs)...
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Hematopoietic effect of deer antler extract fermented by Bacillus subtilis on murine marrow cells

Park Y, Choi HS, Lee HS, Suh HJ

BACKGROUND/OBJECTIVES: We examined the chemical composition and the effect of fermented deer antler on hematopoietic factors in bone marrow cells. MATERIALS/METHODS: For the preparation of fermented deer antler extract (FAB), fermentation...
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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes

Choi CH, Kim TH, Sung YK, Choi CB, Na YI, Yoo H, Jun JB

BACKGROUND/AIMS: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this...
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Vascular Leiomyoma in the Head and Neck Region: 11 Years Experience in One Institution

Yoon TM, Yang HC, Choi YD, Lee DH, Lee JK, Lim SC

  • KMID: 2468439
  • Clin Exp Otorhinolaryngol.
  • 2013 Sep;6(3):171-175.
OBJECTIVES: Vascular leiomyoma is an uncommon benign tumor of smooth muscle origin that arises from the muscularis layer of blood vessel walls. We report our experiences with the clinical manifestations,...
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Effect of 4-hexylresorcinol on Blood Coagulation and Healing of Injured Vessel in a Rat Model

Park YT, Park SY, Kim MK, Kim SG, Park YW, Kwon KJ

  • KMID: 2186230
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2013 Sep;35(5):284-293.
PURPOSE: For reconstruction of craniomaxillofacial defects caused by tumor, trauma, infection etc, free flap transplantation with microvascular surgery is a very useful method. Thrombus formation at the anastomosis site is...
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The Relationship between Oxygen Saturation and Color Alteration of a Compromised Skin Flap: Experimental Study on the Rabbit

Prasetyono TOH, Adianto S

BACKGROUND: The aim of this study was to collect important data on the time of oxygen saturation change in relation to skin flap color alteration using non-invasive pulse oximetry to...
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Recanalization of Acute Intracranial Artery Occlusion Using Temporary Endovascular Bypass Technique

Suh SH, Lee KY, Seo KD, Lim SM, Roh HG, Kim BM

PURPOSE: The purpose of this study is to present our preliminary experience of the temporary endovascular bypass (TEB) technique using an Enterprise stent for recanalization of acute intracranial artery (IA)...
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Microsurgical Extraction of a Malfunctioned Pipeline Embolization Device Following Complete Deployment

Ding D, Liu KC

The Pipeline Embolization Device (PED) is an effective treatment approach for complex intracranial aneurysms. Intraprocedural complications during PED deployment are seldom reported. We report a rare complication of a PED...
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Comparative Results of the Patients with Intracerebral and Intra-sylvian Hematoma in Ruptured Middle Cerebral Artery Aneurysms

Lee JG, Moon CT, Chun YI, Roh HG, Choi JW

OBJECTIVE: To clarify the prognosis of the patients with intra-sylvian hematoma (ISH) and intracerebral hematoma (ICH) in ruptured middle cerebral artery (MCA) aneurysms. METHODS: We categorized hematoma into ISH and ICH...
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The Role of Adiponectin in Secondary Inflammatory Reaction in Cerebral Ischemia

Jung YS, Ha SK, Kim SD, Kim SH, Lim DJ, Choi JI

OBJECTIVE: In this study, we investigate the role of adiponectin in the interaction between leukocytes and endothelium in the secondary inflammatory reaction of cerebral ischemia. METHODS: Adiponectin knock-out mice group (APN-KO)...
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Relation Between Left Atrial Enlargement and Stroke Subtypes in Acute Ischemic Stroke Patients

Shin HY, Jeong IH, Kang CK, Shin DJ, Park HM, Park KH, Sung YH, Shin DH, Noh Y, Lee YB

OBJECTIVE: Increased atrial size is frequently seen in ischemic stroke patients in clinical practice. There is controversy about whether left atrial enlargement (LAE) should be regarded as a risk factor...
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Diffusion Tensor Imaging Changes Correlate with Clinical Progression in Vascular Mild Cognitive Impairment and Vascular Dementia of Subcortical Type

Ryoo NY, Yoon BN, Yoon CW, Ahn JH, Choi JY, Lim MK, Kwon H, Park JS, Lee JM, Choi SH

BACKGROUND: Cerebral small vessel disease (SVD) induces vascular cognitive impairment (VCI) such as subcortical vascular dementia (SVaD) and subcortical vascular mild cognitive impairment (svMCI). We compared MRI parameters between SVaD...
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Rupture of a Brachial Artery Caused by a Humeral Osteochondroma

Kong CB, Lee KY, Cho SH, Song WS, Cho WH, Jeon DG, Lee SY

  • KMID: 2336294
  • J Korean Orthop Assoc.
  • 2013 Aug;48(4):297-301.
Pseudoaneurysm resulting from vascular impingement by an osteochondroma is extremely rare. The authors report on the case of a 16-year-old male who had a brachial artery pseudoaneurysm and vessel rupture...
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