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Optimized Image-Based Surrogate Endpoints in Targeted Therapies for Glioblastoma: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials

Suh CH, Kim HS, Jung SC, Choi CG, Kim SJ, Kim KW

OBJECTIVE: We aimed to determine the optimized image-based surrogate endpoints (IBSEs) in targeted therapies for glioblastoma through a systematic review and meta-analysis of phase III randomized controlled trials (RCTs). MATERIALS AND...
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Prediction of dental caries in 12-year-old children using machine-learning algorithms

Yang YH, Kim JS, Jeong SH

OBJECTIVES: The decayed-missing-filled (DMFT) index is a representative oral health indicator. Prediction of DMFT index is an important basis for the development of public oral health care projects and strategies...
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Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections

Lee JH, Yim HE, Yoo KH

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children...
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Association between the incidence and mortality rates for corpus uteri cancer and human development index (HDI): a global ecological study

Khazaei Z, Goodarzi E, Sohrabivafa M, Naemi H, Mansori K

OBJECTIVE: The aim of this study was to determine the association between the incidence of and mortality due to corpus uteri cancer (CUC) and the human development index (HDI) across...
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Determinants of Circulating Soluble Leptin Receptor and Free Leptin Index in Indonesian Pre-Pubertal Obese Male Children: A Preliminary Cross-Sectional Study

Hendarto A, Nagrani DG, Meiliana A, Sastroasmoro S, Sjarif DR

PURPOSE: This study aimed to investigate the clinical and metabolic determinants of circulating soluble leptin receptor (CSLR) and free leptin index (FLI) in pre-pubertal obese male children. METHODS: We conducted a...
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Effect Modification of Acetaldehyde Dehydrogenase 2 rs671 Polymorphism on the Association between Alcohol Intake and Blood Pressure: the Dong-gu Study

Kim HY, Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Shin MH

BACKGROUND: Elevated blood pressure is a major preventable cause of cardiovascular diseases. Alcohol consumption is a well-known risk factor of elevated blood pressure. The aldehyde dehydrogenase 2 (ALDH2) polymorphism is...
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Preoperative Cardiac Computed Tomography Characteristics Associated with Recurrent Aortic Regurgitation after Aortic Valve Re-Implantation

Ahn Y, Koo HJ, Lee S, Kim DH, Song JM, Kang DH, Song JK, Kim HJ, Kim JB, Jung SH, Choo SJ, Chung CH, Lee JW, Kang JW, Yang DH

OBJECTIVE: To identify the preoperative cardiac computed tomography (CT) factors influencing postoperative recurrent aortic regurgitation (AR) in patients who underwent aortic valve repair with the re-implantation technique (David operation) due...
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Factors Related to Suicide Ideation in Older Women Living Alone

Ryu SI, Park YH

PURPOSE: This study aimed to investigate suicide ideation and attempts in older women living alone and to identify the factors affecting suicide ideation. METHODS: This is a cross-sectional correlational study using...
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Effect of Knowledge and Attitudes of Cancer Pain Management and Patient-Centered Care on Performance of Cancer Pain Management among Nurses at an Oncology Unit

Kim M, Lee YM

PURPOSE: The purpose of this study was to identify factors that influence the performance of cancer pain management among nurses in an oncology unit. METHODS: The participants of this study were...
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Influences of Patient Activation on Diabetes Self-Care Activities and Diabetes-Specific Distress

Choi S, Kim SH

PURPOSE: The purpose of the study was to evaluate the influence of patient activation on diabetes self-care activities and diabetes-specific distress among patients with type 2 diabetes mellitus. METHODS: This cross-sectional...
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Association of Soybean Food Intake and Cardiometabolic Syndrome in Korean Women: Korea National Health and Nutrition Examination Survey (2007 to 2011)

Jun SH, Shin WK, Kim Y

BACKGROUND: Soybean food consumption has been considered as a possible way to lower incidence of cardiometabolic syndrome (CMS) among Asians. However, results from studies investigating its efficacy on CMS in...
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Macular Pigment Optical Density in the Korean Population: a Cross Sectional Study

Hong IH, Jung WH, Lee JH, Chang IB

BACKGROUND: To evaluate the macular pigment optical density (MPOD) with age in the Korean population using the Macular Pigment Screener II (MPSII®). METHODS: One hundred and twenty-six eyes were retrospectively reviewed....
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Clinical Outcomes of Small Incision Lenticule Extraction in Myopia: Study of Vector Parameters and Corneal Aberrations

Kwak JJ, Jun I, Kim EK, Seo KY, Kim TI

PURPOSE: To investigate clinical outcomes of small incision lenticule extraction (SMILE) including vector parameters and corneal aberrations in myopic patients. METHODS: This retrospective, observational case series included 57 eyes (29 patients)...
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Factors Affecting New Graduate Nurses' Intention on Retention in Hospitals: Focused on Nursing Organizational Culture, Empowering Leadership and Organizational Socialization

Kim EG, Jung MS, Kim JK, You SJ

PURPOSE: The purpose of this study was to investigate relationships among intention of retention, nursing organizational culture, empowering leadership and organizational socialization of new graduate nurses, and identify factors affecting...
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Clinical Efficacy of Real-Time Sonoelastography for the Follow-Up of Congenital Sternocleidomastoid Muscle Torticollis

Jeong MR, Lee IS, Shin YB, Song YS, Park S, Song JW, Moon JI

PURPOSE: To evaluate the clinical efficacy of real-time sonoelastography (RTS) for the follow-up of congenital muscular torticollis, based on measurements of muscle elasticity. MATERIALS AND METHODS: Thirty-four infants (23 male, 11...
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Relationship Between Epicardial Fat Volume and Coronary Microvascular Dysfunction in Patients with Chest Pain and Unobstructed Coronary Arteries

Quah JX, Sargent S, Nel K, Anstey CM, Stanton T, Greaves K

OBJECTIVE: Epicardial fat (EF) is metabolically active adipose tissue positioned between the epicardial surface of the heart and the pericardium. We investigated whether there is a relationship between EF and...
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The Difference in Intraocular Pressure before and after Visual Field Test Measured by Rebound Tonometer

Park JH, Kim JY, Lee EK, Lee HJ, Jeong JH, Lee SY

PURPOSE: To investigate the effect of a visual field (VF) test on intraocular pressure (IOP) and relevant parameters in a normal group and an open-angle glaucoma group, and to determine...
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Circulating Tumor Cell Number Is Associated with Primary Tumor Volume in Patients with Lung Adenocarcinoma

Kang BJ, Ra SW, Lee K, Lim S, Son SH, Ahn JJ, Kim BC

BACKGROUND: Circulating tumor cells (CTCs) are frequently detected in patients with advanced-stage malignant tumors and could act as a predictor of poor prognosis. However, there is a paucity of data...
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Early functional outcomes after condylar-stabilizing (deep-dish) versus standard bearing surface for cruciate-retaining total knee arthroplasty

Stirling P, Clement ND, MacDonald , Patton JT, Burnett R, Macpherson GJ

AIMS: The primary study aim was to compare early knee-specific function of patients undergoing cemented total knee arthroplasty (TKA) with either a cruciate-retaining (CR) polyethylene insert or a highly congruent...
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History of Migraine and Volume of Brain Infarcts: The Italian Project on Stroke at Young Age (IPSYS)

Giuli VD, Besana M, Grassi M, Zedde M, Zini A, Lodigiani , Marcheselli S, Cavallini , Micieli G, Rasura M, DeLodovici ML, Tomelleri , Checcarelli N, Chiti A, Giorli E, Sette MD, Tancredi L, Toriello A, Braga M, Morotti A, Poli L, Caria F, Gamba M, Patella R, Spalloni A, Simone AM, Pascarella R, Beretta S, Fainardi E, Padovani A, Gasparotti R, Pezzini A, the Italian Project on Stroke in Young Adults (IPSYS) Investigators

BACKGROUND AND PURPOSE: Migraine has been shown to increase cerebral excitability, promote rapid infarct expansion into tissue with perfusion deficits, and result in larger infarcts in animal models of focal...
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