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Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells

Kim HJ, You MK, Lee YH, Kim HJ, Adhikari D, Kim HA

BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the...
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Pear pomace ethanol extract improves insulin resistance through enhancement of insulin signaling pathway without lipid accumulation

You MK, Kim HJ, Rhyu J, Kim HA

BACKGROUND/OBJECTIVES: The anti-diabetic activity of pear through inhibition of α-glucosidase has been demonstrated. However, little has been reported about the effect of pear on insulin signaling pathway in obesity. The...
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Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells

You MK, Kim MS, Jeong KS, Kim E, Kim YJ, Kim HA

BACKGROUND/OBJECTIVES: The present study was conducted to examine the inhibitory effect of loquat leaves on MDA-MB-231 cell proliferation and invasion. MATERIALS/METHODS: Female athymic nude mice were given a subcutaneous (s.c.) inoculation...
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Inhibitory effect of Erythronium japonicum on the human breast cancer cell metastasis

You MK, Kim MS, Rhyu J, Bang MA, Kim HA

BACKGROUND/OBJECTIVES: In this study, the inhibitory effect of Erythronium japonicum extracts on the metastasis of MDA-MB-231 human breast cancer cell line was determined. MATERIALS/METHODS: Cells were cultured with DMSO or with...
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St. John's Wort (Hypericum perforatum) stimulates human osteoblastic MG-63 cell proliferation and attenuates trabecular bone loss induced by ovariectomy

You MK, Kim DW, Jeong KS, Bang MA, Kim HS, Rhuy J, Kim HA

BACKGROUND/OBJECFTIVES: The effect of St. John's Wort extract (SJW) on MG-63 cell proliferation and trabecular bone loss induced by ovariectomy was examined. MATERIALS/METHODS: Proliferation, expression of estrogen receptor (ER) alpha and...
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Effect of St. John's Wort (Hypericum perforatum) on obesity, lipid metabolism and uterine epithelial proliferation in ovariectomized rats

You MK, Rhuy J, Jeong KS, Bang MA, Kim MS, Kim HA

  • KMID: 2313742
  • Nutr Res Pract.
  • 2014 Jun;8(3):292-296.
BACKGROUND/OBJECTIVES: This study was conducted to assess the potential of St. John's Wort (Hypericum perforatum) to prevent obesity and abnormalities in lipid metabolism induced by ovariectomy in a rat model...
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Pear pomace water extract inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes

Rhyu J, Kim MS, You MK, Bang MA, Kim HA

  • KMID: 2313708
  • Nutr Res Pract.
  • 2014 Feb;8(1):33-39.
Obesity occurs when a person's calorie intake exceeds the amount of energy burns, which may lead to pathologic growth of adipocytes and the accumulation of fat in the tissues. In...
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Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line

Kim MS, You MK, Rhuy DY, Kim YJ, Baek HY, Kim HA

  • KMID: 2392039
  • Nutr Res Pract.
  • 2009 Dec;3(4):259-264.
We examined the inhibitory effects of loquat methanol extract on the adhesion, migration, invasion and matrix metalloproteinase (MMP) activities of MDA-MB-231 human breast cancer cell line. Cells were cultured with...
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Treatment of Kienbock's Disease Using Fascia Latae: Two Cases Report

Kang JD, You MK, Yoo HJ, Lee JH

Avascular necrosis of the carpal lunate (Kienbock's Disease) was first described by Peste in 1843. It's etiology is still unknown. Since Lippman, in 1949, there have been many operative treatments...
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Reapir of the Torn Achilles Tendon, Using the Plantaris Tendon

Kang JD, You MK, Yoo HJ, Ha PS

A major problem in the repair of the torn Achilles tendon has been providing the restoration of the anatomic continuity such that virtually normal plantar flexion power and ankle mobility...
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BCG Osteomyelitis: A Case Report

Kang JD, Yoo HJ, Jang SW, You MK

BCG osteomyelitis occurs in the infants and children as complication of BCG vaccination and its occurrence is very rare. It involves the metaphysis of the long bone and its development...
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The Treatment of Supracondylar Fracture of the Humerus in Children

Kang JD, You MK, Yoo HJ, Jang SW

Supracondylar fracture of the humerus is the most common fracture of the elbow in children For period of 4 years from Jan. 1980 to Dec. 1983, 54 children with dispaced...
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Phantom Phenomena in Traumatic Amputation

Lee EY, Kim DE, You MK

Sixty amputees who had traumatic amputations due to industrial accidents were examined on their phantom limb and phantom pain phenomena and the following results were obtained. 1. Fifty-three (93%) of...
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