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Cloning of Xenopus laevis TRPV2 by Gene Prediction

Lee JY, Shim WS, Oh U

  • KMID: 1572616
  • Genomics Inform.
  • 2005 Mar;3(1):24-29.
TRPV2 is a non-specific cation channel expressed in sensory neurons, and activated by noxious heat. Particularly, TRPV2 has six transmembrane domains and three ankyrin repeats. TRPV2 has been cloned from...
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Temporal Inhibition of FGF Signal on Endoderm Formation during Early Xenopus laevis Embryogenesis

Cha SW, Park MJ

  • KMID: 2224513
  • Korean J Anat.
  • 2003 Dec;36(6):463-468.
Our previous results showed that FGF signaling, which is important for the mesoderm and neuroectoderm induction, should be blocked for the endoderm formation in Xenopus. Here, Xenopus embryos were collected...
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Effect of ginsenosides on the desflurane modulation in the recombinant serotonin type 3A receptor expressed in Xenopus laevis oocytes

Choi SH, Kim MK, Koo BN, Min KT

BACKGROUND: Postoperative nausea and vomiting (PONV) is the most frequent and discomforting side effect following general anesthesia. Most volatile anesthetics have a potent effect on serotonin (5-hydroxydtryptamine, 5-HT) type 3...
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Osteocalcin Expression and Mineralization in Developing Tooth of Xenopus laevis

Park JH, Kwon KT, Park BK, Lee YH

Osteocalcin (OC) is the most abundant noncollagenous protein of extracellular matrix in the bone. In an OC deficient mouse, bone formation rates are increased in cancellous and cortical bones. OC...
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Na, K-ATPase beta2 isoform (atp1b2) expressed in the retina of Xenopus

Rahman MM, Park BY

The ubiquitous Na, K-ATPase is a membrane-bound ion pump located in the plasma membrane in all animal cells and plays an essential role in a variety of cellular functions. Studies...
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Spatiotemporal regulation of fibroblast growth factor signal blocking for endoderm formation in Xenopus laevis

Cha SW, Lee JW, Hwang YS, Chae JP, Park KM, Cho HJ, Kim DS, Bae YC, Park MJ

We have previously shown that the inhibition of fibroblast growth factor (FGF) signaling induced endodermal gene expression in the animal cap and caused the expansion of the endodermal mass in...
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Isolation and Expression Profile of the Ca(2+)-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis

Lee RM, Ryu RH, Jeong SW, Oh SJ, Huang H, Han JS, Lee CH, Lee CJ, Jan LY, Jeong SM

To clone the first anion channel from Xenopus laevis (X. laevis), we isolated a calcium-activated chloride channel (CLCA)-like membrane protein 6 gene (CMP6) in X. laevis. As a first step...
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Expression analysis of ciliary rootlet coiled coil protein mRNA during Xenopus development

Rahman MM, Kim IS, Ahn DC, Cho HS, Kim WI, Kim B, Shin GW, Kwon J, Akanda MR, Park BY

Ciliary rootlet coiled coil protein (CROCC), the structural component that originates from the basal body at the proximal end of the ciliary rootlet, plays a crucial role in maintaining the...
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Screening of Interacting Proteins with PV.1 as Downstream Factors of BMP Signal

Hwang YS, Chae JP, Kim DS, Park KM, Bae YC, Park MJ

  • KMID: 2224459
  • Korean J Anat.
  • 2007 Sep;40(3):203-210.
Homeodomain transcription factors functioning downstream of BMP ventral pathway have been reported to share similar domain of roles in mesoderm patterning along the dorsal-ventral axis. To elucidate the differential role...
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Amino acid residues involved in agonist binding and its linking to channel gating, proximal to transmembrane domain of 5-HT3A receptor for halothane modulation

Kim MK, Min KT, Koo BN

BACKGROUND: The 5-hydroxytryptamine type 3 (5-HT3) receptor is a member of the Cys-loop superfamily of ligand-gated ion channels (LGICs) and modulated by pharmacologic relevant concentrations of volatile anesthetics or n-alcohols...
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Transcriptional Regulation of the Xbr-1a/Xvent-2 Gene by BMP-4 Signaling during Xenopus Embryonic Development

Kim JB, Lee HS, Roh DH, Hwang YS, Xu RH, Kung HF, Bae YC, Park MJ

  • KMID: 2224548
  • Korean J Anat.
  • 2000 Oct;33(5):595-608.
BMP-4 signaling is mediated through Smad proteins which may translocate to the nucleus to activate transcription. Little is known about how BMP-4 signaling regulates the transcription of its target genes,...
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Regulation of Antiarrhythmic Drug Propafenone Effects on the C-type KV1.4 Potassium Channel by PHo and K+

Wang Z, Wang S, Li J, Jiang X, Wang N

The effects of the antiarrhythmic drug propafenone at c-type kv1.4 channels in Xenopus laevis oocytes were studied with the two-electrode voltage-clamp techinique. Defolliculated oocytes (stage V-VI) were injected with transcribed...
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Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development

Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J

  • KMID: 1123768
  • Exp Mol Med.
  • 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be...
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A Differential Effect of Intracellular ATP on Skeletal-and Smooth Muscle-Type KATP Channel Activities

Kwon OD, Lim JG, Kim HG, Kim DK, Hwang JS, Park KG, Park SH, Cho CH, Lee IK, Song DK

  • KMID: 2331749
  • J Korean Diabetes Assoc.
  • 2003 Aug;27(4):332-342.
BACKGROUND: The ATP-sensitive potassium (KATP) channel comprises an inwardly- rectifying K+ channel (Kir) and a sulfonylurea receptor(SUR). This study investigated the mechanism of different ATP sensitivity between skeletal-(Kir6.2/SUR2A) and smooth...
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Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

Kwak JO, Kim HW, Oh KJ, Kim DS, Han KO, Cha SH

  • KMID: 1056233
  • Exp Mol Med.
  • 2005 Jun;37(3):204-212.
The organic anion transporters (OAT) have recently been identified. Although the some transport properties of OATs in the kidney have been verified, the regulatory mechanisms for OAT's functions are still...
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Inhibition of the Human Ether-a-go-go-related Gene (HERG) K+ Channels by Lindera erythrocarpa

Hong HK, Yoon WJ, Kim YH, Yoo ES, Jo SH

Lindera erythrocarpa Makino (Lauraceae) is used as a traditional medicine for analgesic, antidote, and antibacterial purposes and shows anti-tumor activity. We studied the effects of Lindera erythrocarpa on the human...
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