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Cerebrotendinous xanthomatosis in a 10-year-old male presenting with Achilles tendon xanthoma and mild intellectual disability: A case report

Yoon JH, Kim KY, Lee SY, Kim SY, Lee YA, Ki CS, Song J, Shin CH, Lee YJ

Cerebrotendinous xanthomatosis (CTX) is a rare genetic disease caused by a deficiency of enzymes for the synthesis of bile acid, resulting in the accumulation of cholestanol with reduced chenodeoxycholic acid...
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Epidemiological characteristics of varicella outbreaks in the Republic of Korea, 2016–2020

Kim EY, Park C, Lee G, Jeong S, Song J, Lee DH

Objectives We described the trends and epidemiological characteristics of varicella outbreaks from 2016 to 2020 in the Republic of Korea. Methods We investigated variables such as the outbreak setting, age of...
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Survey on the Status of Breastfeeding in Korean Medical Institution Workers

Kim TH, Chung SH, Kim JH, Ahn Y, Shin SM, Lee WR, Choi EK, Lee J, Shin HJ, Jung E, Heo JS, Lee JA, Lee SM, Bae SP, Song J, Kim CY, Yi DY

Background: Human breast milk is essential and provides irreplaceable nutrients for early humans. However, breastfeeding is not easy for various reasons in medical institution environments. Therefore, in order to improve...
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A Retrospective Population-Based Survival Study of Idiopathic Pulmonary Arterial Hypertension in Korea

Jang SY, Kim EK, Huh J, Song J, Kang IS, Park SW, Kim DK, Chang SA

Background: Few studies used nationwide data to assess the survival rates (SRs) and death risk for idiopathic pulmonary arterial hypertension (IPAH; ICD-10 I27.0) in Korea. Methods: IPAH data (N = 9,017;...
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Usefulness of Silent MRA for Evaluation of Aneurysm after Stent-Assisted Coil Embolization

Kim YN, Choi JW, Lim YC, Song J, Park JH, Jung WS

Objective: To determine the usefulness of Silent MR angiography (MRA) for evaluating intracranial aneurysms treated with stent-assisted coil embolization. Materials and Methods: Ninety-nine patients (101 aneurysms) treated with stent-assisted coil embolization...
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The Waiting List Mortality of Pediatric Heart Transplantation Candidates in Korea before the Pediatric Ventricular Assist Device Era

Jeung MS, Kim MJ, Huh J, Kang IS, Kim GB, Yu JJ, Song J

Background: Despite advancements in heart transplantation for pediatric patients in Korea, the waiting list mortality has not been reported. Therefore, we investigated the waiting list mortality rate and factors associated...
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Analysis of the Current Status of Liver Cancer Screening Institutions and Proficiency of Institutions that Conduct Alpha-fetoprotein Tests

Lee JK, Kim TS, Song J, Lee WI, Jang D, Kim Y, Suh M, Chun S, Park HD

Background: We sought to evaluate the performance of alpha-fetoprotein (AFP) qualitative reagents and understand the current status of AFP testing by liver cancer screening institutions. Methods: Using commercial control materials or...
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An Open Pilot Trial of Written Exposure Therapy for Patients With Post-Traumatic Stress Disorder in Korea

Park JE, Choi KS, Han YR, Kim JE, Song J, Yu JC, Yun JA

Objective Written exposure therapy (WET) is exposure therapy for post-traumatic stress disorder (PTSD). Compared to evidencebased treatments for PTSD, WET requires only five sessions, has a shorter session time, and...
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Mitofusin-2 Promotes the EpithelialMesenchymal Transition-Induced Cervical Cancer Progression

Ahn SY, Song J, Kim YC, Kim MH, Hyun YM

High expression of mitofusin-2 (MFN2), a mitochondrial fusion protein, has been frequently associated with poor prognosis of patients with cervical cancer. Here, we aimed to identify the function of MFN2...
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Symptomatic Construct Failure after Metastatic Spine Tumor Surgery

Kumar N, Patel R, Tan JH, Song J, Pandita N, Hey DHW, Lau LL, Liu G, Thambiah J, Wong HK

Study Design: Retrospective cohort study. Purpose: To evaluate the incidence and presentation of symptomatic failures (SFs) after metastatic spine tumor surgery (MSTS). To identify the associated risk factors. To categorize SFs...
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Recent Trends in Creatinine Assays in Korea: LongTerm Accuracy-Based Proficiency Testing Survey Data by the Korean Association of External Quality Assessment Service (2011–2019)

Jeong TD, Cho EJ, Lee K, Lee W, Yun YM, Chun S, Song J, Min WK

Background: Accurate serum creatinine (Cr) concentration measurement is essential for evaluating kidney function. In 2011, the Korean Association of External Quality Assessment Service (KEQAS) launched an accuracy-based Cr proficiency testing...
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Wnt-C59 inhibits proinflammatory cytokine expression by reducing the interaction between β-catenin and NF-κB in LPS-stimulated epithelial and macrophage cells

Jang J, Song J, Sim I, Yoon Y

Dysregulation of the Wnt pathway causes various diseases including cancer, Parkinson’s disease, Alzheimer’s disease, schizophrenia, osteoporosis, obesity and chronic kidney diseases. The modulation of dysregulated Wnt pathway is absolutely necessary....
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First Report of Roseomonas aerofrigidensis Isolated from the Peritoneal Fluid of a Gastric Cancer Patient

Jang E, Kim SM, Song J, Nguyen LP, Lee H

Roseomonas aerofrigidensis is a gram-negative, strictly aerobic, non-motile bacterium, which was first isolated in 2017 in South Korea. We present the first report of the isolation of R.aerofrigidensis from the...
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Hard Ticks as Vectors Tested Negative for Severe Fever with Thrombocytopenia Syndrome in Ganghwa-do, Korea during 2019-2020

Jin K, Koh YJ, Ahn SK, Cho J, Lim J, Song J, Lee J, Gong YW, Kwon MJ, Kwon HW, Bahk YY, Kim TS

This study aimed to characterize the seasonal abundance of hard ticks that transmit severe fever with thrombocytopenia syndrome virus from April to November 2019 and 2020 on Ganghwa-do, Incheon Metropolitan...
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Korean Clinical Imaging Guidelines for the Appropriate Use of Chest MRI

Song J, Nam BD, Yoon SH, Yoo JY, Jeong YJ, Yeo CD, Lim SY, Lee SY, Kim HK, Kim BH, Jin KN, Yong HS

MRI has the advantages of having excellent soft-tissue contrast and providing functional information without any harmful ionizing radiation. Although previous technical limitations restricted the use of chest MRI, recent technological...
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Tissue Factor Pathway Inhibitor Levels and Thrombin Generation in Hemorrhagic Disease

Lee S, Song J

Background: Tissue factor pathway inhibitor (TFPI) regulates blood coagulation. To treat hemorrhagic disease, studies have been conducted to achieve a hemostatic effect by inhibiting TFPI. In this study, blood TFPI...
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Establishment of Pediatric Reference Intervals for Routine Laboratory Tests in Korean Population: A Retrospective Multicenter Analysis

Sung JY, Seo JD, Ko DH, Park MJ, Hwang SM, Oh S, Chun S, Seong MW, Song J, Song SH, Park SS

Background: Reference intervals defined for adults or children of other ethnicities cannot be applied in the evaluation of Korean pediatric patients. Pediatric reference intervals are difficult to establish because children...
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Updated recommendations for the treatment of venous thromboembolism

Hong J, Ahn SY, Lee YJ, Lee JH, Han JW, Kim KH, Yhim HY, Nam SH, Kim HJ, Song J, Kim SH, Bang SM, Kim JS, Mun YC, Bae SH, Kim HK, Jang S, Park R, Choi HS, Kim I, Oh D, obotKSoHTaHWP

Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, is a condition characterized by abnormal blood clot formation in the pulmonary arteries and the deep venous vasculature. It...
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Noncontrast Computed Tomography-Based Radiomics Analysis in Discriminating Early Hematoma Expansion after Spontaneous Intracerebral Hemorrhage

Song Z, Guo D, Tang Z, Liu H, Li X, Luo S, Yao X, Song W, Song J, Zhou Z

Objective: To determine whether noncontrast computed tomography (NCCT) models based on multivariable, radiomics features, and machine learning (ML) algorithms could further improve the discrimination of early hematoma expansion (HE) in...
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Regulation of Gut Microbiota Disrupts the Glucocorticoid Receptor Pathway and Inflammation-related Pathways in the Mouse Hippocampus

Rao X, Liu L, Wang H, Yu Y, Li W, Chai T, Zhou W, Ji P, Song J, Wei H, Xie P

An increasing number of studies have recently indicated the important effects of gut microbes on various functions of the central nervous system. However, the underlying mechanisms by which gut microbiota regulate...
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