J Korean Neurol Assoc.  2016 Nov;34(5):353-356. 10.17340/jkna.2016.4.11.

Freezing of Gait in Extrapontine Myelinolysis

Affiliations
  • 1Department of Neurology, Kyung Hee University College of Medicine, Seoul, Korea. ricash@hanmail.net

Abstract

A 65-year-old female visited us due to gait disturbance. A neurological examination showed cognitive impairment, dystonia, myoclonus, bradykinesia, postural instability, and freezing of gait (FOG). She was diagnosed with extrapontine myelinolysis based on her history of hyponatremia and high signal intensities (HSIs) in both striata on T2-weighted images. Her neurological problems including FOG improved over 25 days. In a follow-up MRI 50 days after the onset, HSIs disappeared in the striata but new ones appeared in the pons. FOG may have been related to striatal dysfunction in this patient.

Keyword

Extrapontine myelinolysis; Freezing of gait

MeSH Terms

Aged
Cognition Disorders
Dystonia
Female
Follow-Up Studies
Freezing*
Gait*
Humans
Hypokinesia
Hyponatremia
Magnetic Resonance Imaging
Myelinolysis, Central Pontine*
Myoclonus
Neurologic Examination
Pons
Weather
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