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Influence of the Amount of Fresh Specimen on the Isolation of Tumor Mesenchymal Stem-Like Cells from High-Grade Glioma

Kong SH, Yoo J, Lee D, Moon S, Sung KS, Park SH, Shim JK, Choi RJ, Yoon SJ, Moon JH, Kim EH, Lee SJ, Chang JH, Kang SG

Purpose: A critical indicator of the overall survival of patients with high-grade glioma is the successful isolation of tumor mesenchymal stem-like cells (tMSLCs), which play important roles in glioma progression....
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Transcatheter Aortic Valve Replacement versus Sutureless Aortic Valve Replacement: A Single Center Retrospective Cohort Study

Chung YH, Lee SH, Ko YG, Lee S, Shim CY, Ahn CM, Hong GR, Shim JK, Kwak YL, Hong MK

Purpose: This study sought to compare clinical outcomes between transcatheter aortic valve replacement (TAVR) and sutureless aortic valve replacement (SU-AVR). Materials and Methods: In total, 320 patients with symptomatic severe aortic...
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Perioperative management of patients receiving non-vitamin K antagonist oral anticoagulants: up-to-date recommendations

Kim KS, Song JW, Soh S, Kwak YL, Shim JK

Indications of non-vitamin K antagonist oral anticoagulants (NOACs), consisting of two types: direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitor (rivaroxaban, apixaban, and edoxaban), have expanded over the last...
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Glioblastoma Cellular Origin and the Firework Pattern of Cancer Genesis from the Subventricular Zone

Yoon SJ, Park J, Jang DS, Kim HJ, Lee JH, Jo E, Choi RJ, Shim JK, Moon JH, Kim EH, Chang JH, Lee JH, Kang SG

Glioblastoma (GBM) is a disease without any definite cure. Numerous approaches have been tested in efforts to conquer this brain disease, but patients invariably experience recurrence or develop resistance to...
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Monitored Anesthesia Care for Cardiovascular Interventions

Song JW, Soh S, Shim JK

The interventional cardiology is growing and evolving. Many complex procedures are now performed outside the operating room to manage cardiovascular pathologies which had been traditionally treated with cardiac surgery. Appropriate...
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Anesthetic considerations for a patient with situs inversus totalis undergoing cardiac surgery: A case report

Koo CH, Shim JK, Kim N, Ki Y, Park J, Kim JC

A 58-year-old male patient with situs inversus totalis, a rare congenital malformation characterized by all asymmetric organs being formed as the mirror images of their normal morphologies, underwent mitral valve...
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Anesthetic-induced myocardial protection in cardiac surgery: relevant mechanisms and clinical translation

Soh S, Song JW, Choi N, Shim JK

Cardiac surgery is still associated with complications such as adverse perioperative cardiovascular events. Over the past two decades, many studies have shown that volatile anesthetics and opioids provide myocardial protection...
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Current clinical application of dexmedetomidine for sedation and anesthesia

Kim DS, Na HS, Lee JH, Shin YD, Shim JK, Shin HW, Kang H, Joung KW

Many sedatives are used clinically and include benzodiazepines, barbiturates, antihistamines, propofol, and alpha-2-agonist. Benzodiazepines activate GABA neuronal receptors in the brain and present sedating, hypnotic, anxiolytic, amnestic, and anticonvulsant effects,...
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Dual antiplatelet therapy and non-cardiac surgery: evolving issues and anesthetic implications

Song JW, Soh S, Shim JK

Dual antiplatelet therapy (DAPT) consisting of aspirin plus a P2Y₁₂ inhibitor (clopidogrel, prasugrel, or ticagrelor) is imperative for the treatment of acute coronary syndrome, particularly during the re-endothelialization period after...
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Efficacy of Goal-Directed Therapy Using Bioreactance Cardiac Output Monitoring after Valvular Heart Surgery

Lee S, Lee SH, Chang BC, Shim JK

PURPOSE: We compared the efficacy of postoperative hemodynamic goal-directed therapy (GDT) using a pulmonary artery catheter (PAC) and bioreactance-based noninvasive cardiac output monitoring (NICOM) in patients with atrial fibrillation undergoing...
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Persistent Left Superior Vena Cava Detected Incidentally after Pulmonary Artery Catheterization

Lee HJ, Kim N, Lee H, Shim JK, Song JW

We present a case of pulmonary artery catheter (PAC) placement through the right internal jugular vein, bridging vein and coronary sinus in a patient with previously unrecognized persistent left superior...
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Transcatheter Aortic Valve Implantation in a Patient with Previous Mitral Valve Replacement

Moon SW, Ko YG, Hong GR, Lee S, Chang BC, Shim JK, Kwak YR, Hong MK

Transcatheter aortic valve implantation (TAVI) has shown favorable outcomes in patients with severe symptomatic aortic valve stenosis who are at high surgical risk or are unsuitable candidates for open heart...
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Multidisciplinary Team Approach for Identifying Potential Candidate for Transcatheter Aortic Valve Implantation

Hong SJ, Hong MK, Ko YG, Choi D, Hong GR, Shim JK, Kwak YL, Lee S, Chang BC, Jang Y

PURPOSE: We sought to evaluate the clinical usefulness of decision making by a multidisciplinary heart team for identifying potential candidates for transcatheter aortic valve implantation (TAVI) in patients with symptomatic...
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Effect of 6% Hydroxyethyl Starch 130/0.4 as a Priming Solution on Coagulation and Inflammation Following Complex Heart Surgery

Cho JE, Shim JK, Song JW, Lee HW, Kim DH, Kwak YL

PURPOSE: Prolonged duration of cardiopulmonary bypass aggravates the degree of inflammation and coagulopathy. We investigated the influence of 6% hydroxyethyl starch (HES) 130/0.4 on coagulation and inflammation compared with albumin...
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Echocardiographic detection of left atrial mobile calcium debris of trido valve surgery: a case report

Song Y, Shim JK, Sun JM, Lee B, Kwak YL

Calcification of the cardiac chambers is among the challenges associated with reoperative cardiac surgeries by increasing the risk of systemic embolization. We experienced a case of an unexpected detected mass...
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Successful Treatment of Severe Aortic Stenosis With Transcatheter Aortic Valve Implantation in a Centenarian Patient

Lee YJ, Kim YJ, Lee JH, Ko YG, Shin S, Hong G, Lee S, Chang BC, Shim JK, Kwak YR, Hong MK

Transcatheter aortic valve implantation (TAVI) is a less invasive procedure to treat severe aortic valve stenosis than conventional surgical aortic valve replacement. Furthermore, TAVI has shown similar clinical outcomes as...
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Isolated central venous pressure elevation caused by hematoma formation compressing the superior vena cava following a Bentall operation: a case report

Song Y, Sim J, Seo SJ, Choi SA, Shim JK

We present a case of a patient exhibiting isolated elevation of the central venous pressure with minimal hemodynamic deterioration in an immediate postoperative period after Bentall operation requiring re-exploration. Isolated...
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The Influence of Hypothermia on Transfusion Requirement in Patients Who Received Clopidogrel in Proximity to Off-Pump Coronary Bypass Surgery

Lee BR, Song JW, Kwak YL, Yoo KJ, Shim JK

PURPOSE: Hypothermia adversely affects the coagulation that could be of clinical significance in patients receiving clopidogrel. We evaluated the influence of hypothermia on transfusion requirements in patients undergoing isolated off-pump...
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Successful resuscitation of cardiac arrest caused by CO2 embolism with intra-aortic injection of epinephrine during off-pump coronary bypass surgery: a case report

Lee CS, Yoon YS, Shim JK, Lim HK

Although compressed gas (CO2) blowers have been used safely to aid accurate grafting during off-pump coronary bypass surgery, hemodynamic collapse due to gas embolism into the right coronary artery may...
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Transcatheter Aortic Valve Implantation Using CoreValve by Transaortic Approach

Chun KH, Ko YG, Shim JY, Lee S, Chang BC, Shim JK, Kwak YR, Hong MK

INTRODUCTION: Transcatheter aortic valve implantation (TAVI) is now considered as an alternative treatment option for severe aortic stenosis (AS) patients who cannot undergo surgical aortic valve replacement (AVR). CASE REPORT: We...
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