Korean J Med.
2003 Nov;65(Suppl 3):S727-S732.
Wide QRS tachycardia during treatment with class ic antiarrhythmic agents in a patient with atrial fibrillation: report of 2 cases
- Affiliations
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- 1Division of Cardiology, Wallace Memorial Baptist Hospital, Busan, Korea. doctorsim@yahoo.co.kr
Abstract
- Wide QRS tachycardia may represent a rare proarrhythmic effect of some antiarrhythmic agents. Class Ic antiarrhythmic agents produce rate- dependent ventricular conduction slowing due to use-dependent sodium channel blockade, causing QRS prolongation in cases with an increased heart rate. The authors describe two cases of atrial flutter with 1:1 atrioventricular conduction exhibiting a wide QRS tachycardia while on therapy using flecainide and propafenone, and the difficulty in interpreting the ECG.
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