Korean J Med.  2001 Aug;61(2):201-205.

A case report of malignant paraganglioma with hepatic metastases

Affiliations
  • 1Department of Internal Medicine, Pusan Medical Center, Pusan, Korea. docjun@netsgo.com

Abstract

We report a case of malignant paraganglioma with hepatic metastases. A 70-year old woman developed huge hepatic tumor 2years after complete resection of the retroperitoneal paraganglioma. CT imaging of abdomen revealed huge hepatic masses, which had not been found previously. A needle biopsy on the liver was performed, resulting in a diagnosis of malignant paraganglioma. These tumors are usually benign but can occasionally produce local and distant metastases. Development of metastatic localizations is the only formal proof of malignancy as histology cannot distinguish between benign and malignant paragangliomas. Surgery is the basis of treament and should be performed early in the operable course. Both chemotherapy and radiotherapy could be given, but satisfactory outcomes were not obtained. We suggest that close investigations for metastasis in patient with paraganglioma, seemed benign initially, as well as periodic follow up examinations should be emphasized.

Keyword

Paraganglioma; Liver; Neoplasm; Metastasis

MeSH Terms

Abdomen
Aged
Biopsy, Needle
Diagnosis
Drug Therapy
Female
Follow-Up Studies
Humans
Liver
Neoplasm Metastasis*
Paraganglioma*
Radiotherapy
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