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Retinal Ganglion Cell Layer Thicknesses and Visual Functions in Patients with Bilateral Temporal Optic Atrophy

Kim BG, Park JY, Oh WH, Choi J

PURPOSE: To investigate correlations between macular retinal ganglion cell (RGC) layer thickness and best-corrected visual acuity (BCVA) and visual field parameters in patients with bilateral temporal optic atrophy. METHODS: Thirty eyes...
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Retinal Nerve Fiber Layer and Macular Retinal Ganglion Cell Layer Thicknesses in Healthy Korean Children

Kim Y, Hwang YH

PURPOSE: To measure the thicknesses of the circumpapillary retinal nerve fiber layer (RNFL) and macular retinal ganglion cell-inner plexiform layer (GCIPL) by optical coherence tomography (OCT) in healthy Korean children...
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Comparison of Retinal Ganglion Cell Damage in Glaucoma and Retinal Vein Occlusion by Visual Field

Lee J, Jeon S, Park HY

PURPOSE: We analyzed and compared retinal ganglion cell damage between patients with glaucoma and those with branched retinal vein occlusion (BRVO). We performed two types of visual field examinations. METHODS: We...
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The advantage of topographic prominence-adopted filter for the detection of short-latency spikes of retinal ganglion cells

Ahn J, Choi MH, Kim K, Senok SS, Cho DI, Koo KI, Goo Y

Electrical stimulation through retinal prosthesis elicits both short and long-latency retinal ganglion cell (RGC) spikes. Because the short-latency RGC spike is usually obscured by electrical stimulus artifact, it is very...
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Effect of Anti-vascular Endothelial Growth Factor Antibody on the Survival of Cultured Retinal Ganglion Cells

Lee JM, Bae HW, Lee SY, Seong GJ, Kim CY

PURPOSE: To investigate the effects of anti-vascular endothelial growth factor (VEGF) antibody on the survival of retinal ganglion cell (RGC)-5 cells differentiated with staurosporine under oxidative stress. METHODS: We used real-time...
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Effect of Stimulus Waveform of Biphasic Current Pulse on Retinal Ganglion Cell Responses in Retinal Degeneration (rd1) mice

Ahn KN, Ahn JY, Kim JH, Cho K, Koo KI, Senok SS, Goo YS

A retinal prosthesis is being developed for the restoration of vision in patients with retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Determining optimal electrical stimulation parameters for the prosthesis...
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Characteristics of Light-evoked Retinal Ganglion Cell Activity with Postnatal Maturation in SD Rat

Ye JH, Goo YS

  • KMID: 1590883
  • Korean J Med Phys.
  • 2005 Dec;16(4):214-219.
As part of Korean retinal prosthesis project, we have provided preliminary experimental results regarding voltage parameters for the stimulation of chemically degenerated rabbit retina. Since our APB-treated chemically degenerated retina...
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Waveform Sorting of Rabbit Retinal Ganglion Cell Activity Recorded with Multielectrode Array

Jin GH, Lee TS, Goo YS

  • KMID: 2080301
  • Korean J Med Phys.
  • 2005 Sep;16(3):148-154.
Since the output of retina for visual stimulus is carried by neurons of very diverse functional properties, it is not adequate to use conventional single electrode for recording the retinal...
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Assessment of Retinal Ganglion Cell using Retinal Nerve Fiber Layer Photography in Age-related Macular Degeneration

Oh JY, Chung TY, Kim DM, Yu HG

  • KMID: 2125776
  • J Korean Ophthalmol Soc.
  • 2004 Dec;45(12):2036-2040.
PURPOSE: To determine the loss of ganglion cell layer (GCL) neurons in patients with age-related macular degeneration (AMD) with choroidal neovascularization (CNV). METHODS: Retinal nerve fiber layer (RNFL) photography was...
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The Neuroprotective Effect of Ginexin on Rat Retinal Ganglion Cell in Optic Nerve Crush Injury Model

Kang JH, Park KH, Kim YJ, Kim JH, Kwak WJ

  • KMID: 2125619
  • J Korean Ophthalmol Soc.
  • 2003 Apr;44(4):965-970.
PURPOSE: To investigate the neuroprotective effect of Ginexin (Ginkgo biloba extract) on rat retinal ganglion cell in the optic nerve crush injury model. METHODS: From 1 week before the optic...
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The Neuroprotective Effect of Intravitreally Injected CNTF on Rat Retinal Ganglion Cell in Optic Nerve Crush Injury Model

Kang JH, Park KH, Kim DM

  • KMID: 2337091
  • J Korean Ophthalmol Soc.
  • 2003 Feb;44(2):491-495.
PURPOSE: To make an optic nerve crush injury model and to investigate the neuroprotective effect of intravitreally injected ciliary neurotrophic factor (CNTF) on rat retinal ganglion cells (RGCs) in the...
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The Effect of Heat Shock Protein 70.1 gene (hsp70.1) on Retinal Ganglion Cell Damage after Partial Lesion of the Optic Nerve in Mice

Lee SM, Park KH, Seo JS

  • KMID: 2206316
  • J Korean Ophthalmol Soc.
  • 2002 Dec;43(12):2577-2584.
PURPOSE: Heat shock protein (HSP) 70 has been known to have neuroprotective effect on the retinal ganglion cells (RGCs) in vitro and in a rat glaucoma model. This study was...
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Pilocarpine Induced Expression of Nitric Oxide Synthase in R18A5 Retinal Ganglion Cell Line

Choi KD, Bae JH, Huh K, Chung JH

  • KMID: 2336932
  • J Korean Ophthalmol Soc.
  • 2000 Jul;41(7):1466-1472.
Pilocarpine is a direct cholinergic agonist and reduces intraocular pressure by enhancing aqueous outflow. A recent study reveals that pilocarpine induces apoptotic cell death in retinal ganglion cells; activation of...
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Apoptosis of Retinal Ganglion Cell after Ischemia-reperfusion Injury of Optic Nerve in Rabbits

Park KH, Kim DM

  • KMID: 2205402
  • J Korean Ophthalmol Soc.
  • 1998 Nov;39(11):2687-2700.
To develop a new animal model for ischemia-reperfusion infury of the optic nerve in rabbits and to investigate the pattern of retinal ganglion cell apoptosis and bcl-2 staining in the...
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