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Cellular Localization of RANKL and RANK Production in Giant Cell Tumors of Bone and Tendon Sheath by Immunohistochemistry

Cheong HR, Kang H, Song DE, Cho MS

No abstract available in English.
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NF-kappaB-Mediated Regulation of Osteoclastogenesis

Boyce BF, Xiu Y, Li J, Xing L, Yao Z

Osteoclasts are multinucleated cells formed mainly on bone surfaces in response to cytokines by fusion of bone marrow-derived myeloid lineage precursors that circulate in the blood. Major advances in understanding...
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Regulation of NFATc1 in Osteoclast Differentiation

Kim JH, Kim N

Osteoclasts are unique cells that degrade the bone matrix. These large multinucleated cells differentiate from the monocyte/macrophage lineage upon stimulation by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and receptor...
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Identification of Receptor Activator of Nuclear Factor-kappa B Ligand(RANKL) and Osteoprotegerin(OPG) in Ameloblastoma

Ha WH, Hwang DS, Kim YD, Shin SH, Kim UK, Kim JR, Chung IK

  • KMID: 2190304
  • J Korean Assoc Oral Maxillofac Surg.
  • 2007 Apr;33(2):94-102.
The ameloblastoma is a common odontogenic tumor of the jaw bone and represents approximately 1% of tumor in the jaw. However, it might be able to infiltrate into the adjacent...
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Alterations in Serum Levels of Receptor Activator of Nuclear Factor-kappa B Ligand and Osteoprotegerin in Patients with Head Injury and Fracture

Park SY, Suh KT, Ryu CH, Woo SH, Lee JS, Kim SG

PURPOSE: Receptor activator of nuclear factor-kappa B ligand (RANKL), osteoprotegerin (OPG) have been shown to be important regulators of osteoclastogenesis during bone remodeling, and their expressions were examined during fracture...
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The effect of progressive tensional force on mRNA expression of osteoprotegerin and receptor activator of nuclear factor kappa B ligand in the human periodontal ligament cell

Lee KJ, Lee SI, Hwang CJ, Ohk SH, Tian YS

  • KMID: 1762553
  • Korean J Orthod.
  • 2005 Aug;35(4):262-274.
Tooth movement is a result of mutual physiologic responses between the periodontal ligament and alveolar bone stimulated by mechanical strain. The PDL cell and osteoblast are known to have an...
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Salivary soluble receptor activator of nuclear factor kappa B ligand/osteoprotegerin ratio in periodontal disease and health

Tabari ZA, Azadmehr A, Tabrizi MA, Hamissi J, Ghaedi FB

PURPOSE: The receptor activator of nuclear factor kappa B (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system plays a significant role in osteoclastogenesis, activation of osteoclasts, and regulation of bone resorption. This study...
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Receptor activator of nuclear factor kappa-B gene polymorphisms in Iranian periodontitis and peri-implantitis patients

Kadkhodazadeh M, Baghani Z, Ebadian AR, Kaghazchi , Amid R

PURPOSE: Peri-implantitis and periodontitis are inflammatory and infectious diseases of implant and tooth-supporting tissues. Recently, the role of gene polymorphisms of immune response components in the relevant pathogenesis has been...
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NFATc1 and NFATc3 is Involved in the Expression of Receptor Activator of NF-kappaB Ligand in Activated T Lymphocytes

Heo SJ, Park HJ, Baek JH

  • KMID: 1431127
  • Int J Oral Biol.
  • 2013 Mar;38(1):37-42.
Receptor activator of NF-kappaB ligand (RANKL) is an essential cytokine for osteoclast differentiation, activation and survival. T lymphocytes such as T17 cells, a subset of T helper cells that produce...
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The Relationship between Polymorphisms of Wnt Antagonists Genes and Production of Osteoprotegerin (OPG)-soluble receptor Activator of NF-kappaB Ligand (sRANKL) by Whole Blood Cells

Kim H, Lee DO, Ku SY, Kim SH, Choi YM, Kim JG

  • KMID: 2329527
  • J Reprod Endocrinol.
  • 2012 Apr;4(1):20-29.
OBJECTIVES: To investigate the association between polymorphisms of Wnt antagonists genes and the production of osteoprotegerin (OPG), and soluble receptor activator of nuclear factor-kappaB ligand (sRANKL) by whole blood cells...
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Bone Healing in Ovariectomized-rabbit Calvarial Defect with Tricalcium Phosphate Coated with Recombinant Human Bone Morphogenetic Protein-2 Genetically Engineered in Escherichia coli

Kim JH, Kim CJ, Shin SH

  • KMID: 1704506
  • Maxillofac Plast Reconstr Surg.
  • 2014 Mar;36(2):37-49.
PURPOSE: This study compares the bone formation ability of tricalcium phosphate (TCP) with and without recombinant human bone morphogenetic protein-2 (rhBMP-2) and assesses TCP as a carrier of rhBMP-2. METHODS: Bilateral...
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The Relationship between Wnt Antagonist Genes Polymorphisms and Changes in Production of Osteoprotegerin and Soluble Receptor Activator of NF-kB by Whole Blood Cells after Hormone Therapy

Park KE, Lee DO, Kim H, Ku SY, Kim SH, Choi YM, Kim JG

  • KMID: 2314123
  • Osteoporosis.
  • 2012 Dec;10(3):112-118.
OBJECTIVES: To investigate the relationship between single nucleotide polymorphism (SNP)s in Wnt antagonist genes, and production of osteoprotegerin (OPG) and soluble receptor activator of NF-kappaB ligand (sRANKL) by whole blood...
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Effect of Cornus Officinalis on Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL)-induced Osteoclast Differentiation

Kim JY, Kim YK, Choi MK, Oh J, Kwak HB, Kim JJ

OBJECTIVES: Osteoporosis is a disease of bones that is thought to result from an imbalance between bone resorption and bone formation. Although osteoporosis itself has no symptoms, osteoporosis caused by...
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Bacterial PAMPs and Allergens Trigger Increase in [Ca2+]i-induced Cytokine Expression in Human PDL Fibroblasts

Son GY, Shin DM, Hong JH

An oral environment is constantly exposed to environmental factors and microorganisms. The periodontal ligament (PDL) fibroblasts within this environment are subject to bacterial infection and allergic reaction. However, how these...
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Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions

Fu YX, Gu JH, Zhang YR, Tong XS, Zhao HY, Yuan Y, Liu XZ, Bian JC, Liu ZP

The purpose of this study was to determine whether osteoprotegerin (OPG) could affect osteoclat differentiation and activation under serum-free conditions. Both duck embryo bone marrow cells and RAW264.7 cells were...
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The Relationship between Wnt Signaling Pathway Gene Polymorphisms and Production of Osteoprotegerin and Soluble Receptor Activator of NF-kB by Whole Blood Cells

Lee DY, Kim H, Ku SY, Suh CS, Kim SH, Choi YM, Kim JG

  • KMID: 2321566
  • J Korean Soc Osteoporos.
  • 2010 Aug;8(2):178-187.
OBJECTIVES: To investigate the relationship between single nucleotide polymorphisms (SNPs) in Wnt signal pathway genes, and production of osteoprotegerin (OPG) and soluble receptor activator of NF-kappaB ligand (sRANKL) by whole...
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The Relationship Between Leptin and Adrenergic Receptors Genes Polymorphisms and Changes in Production of Osteoprotegerin and Soluble Receptor Activator of NF-kappaB by Whole Blood Cells after Hormone Therapy

Park KE, Lee HJ, Kim H, Ku SY, Kim SH, Choi YM, Kim JG

  • KMID: 2212595
  • J Reprod Endocrinol.
  • 2013 Apr;5(1):18-26.
OBJECTIVES: To investigate the relationship between single nucleotide polymorphisms (SNPs) in leptin and adrenergic receptors genes, and the production of osteoprotegerin (OPG) and soluble receptor activator of NF-kappaB ligand (sRANKL)...
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Expression of Receptor Activator of NF-kappaB Ligand and Osteoprotegerin in Cholesteatoma

Byun JY, Cha CI, Yeo SG, Kim SW, Cho JS

  • KMID: 2276455
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Aug;48(8):955-960.
BACKGROUND AND OBJECTIVES: Bone resorption in middle ear cholesteatoma is mostly responsible for serious complications of the disease, but the pathogenesis of destruction due to bone resorption has not been...
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Methanol Extract of Croton Pycnanthus Benth. Inhibits Osteoclast Differentiation by Suppressing the MAPK and NF-kappaB Signaling Pathways

Lee J, Kim HH

BACKGROUND: Osteoclasts are differentiated from monocytes/macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-kappa B (NF-kappaB) ligand (RANKL). Croton pycnanthus Benth. (CPB) is a herbal plant that belongs to...
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TNFalpha Increases the Expression of beta2 Adrenergic Receptors in Osteoblasts

Baek K, Lee HL, Hwang HR, Park HJ, Kwon A, Qadir AS, Baek JH

  • KMID: 1445158
  • Int J Oral Biol.
  • 2011 Dec;36(4):173-178.
Tumor necrosis factor alpha (TNFalpha) is a multifunctional cytokine that is elevated in inflammatory diseases such as atherosclerosis, diabetes and rheumatoid arthritis. Recent evidence has suggested that beta2 adrenergic receptor...
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