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Relationship of Oral Bacterial Load Over One Year of Smoking Cessation

Kim S, Seo MS, Hwang SJ

BACKGROUND: Smoking exerts an adverse effect on the periodontal tissue by reorganizing the ecosystem of oral microorganisms and is considered to be an important factor in the development of periodontal...
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Real-time PCR quantification of 9 periodontal pathogens in saliva samples from periodontally healthy Korean young adults

Choi H, Kim E, Kang J, Kim HJ, Lee JY, Choi J, Joo JY

PURPOSE: Few studies have examined periodontal pathogens from saliva samples in periodontally healthy young adults. The purposes of this study were to determine the prevalence of periodontopathic bacteria and to...
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Red fluorescence of oral bacteria is affected by blood in the growth medium

Jeong SH, Yang YH, Lee MA, Kim SY, Kim JS

OBJECTIVES: Dental plaque emits red fluorescence under a visible blue light near the ultra-violet end of the light spectrum. The fluorescence characteristics of each microorganism have been reported in several...
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Detection of Bacterial Species in Chronic Periodontitis Tissues at Different Stages of Disease Severity

Yoon DL, Kim S, Song H, Kim YG, Lee JM, Kim J

The goal of this research was to determine the relationship between the stage of chronic periodontitis and the presence of six bacterial pathogens (Aggregatibacter actinomycetemcomitans: AA, Fusobacterium nucleatum: FN, Porphyromonas...
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Development of Quantitative Real-Time PCR Primers for Detection of Prevotella intermedia

Park SN, Kook JK

Prevotella intermedia-specific quantitative real-time PCR (qPCR) primers were previously designed based on the nucleotide sequences of RNA polymerase beta-subunit gene (rpoB). However, the several clinical strains isolated from Korean populations...
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Humoral immune responses to periodontal pathogens in the elderly

Shet U, Oh HK, Chung HJ, Kim YJ, Kim OS, Lim HJ, Shin MH, Lee SW

PURPOSE: Elderly people are thought to be more susceptible to periodontal disease due to reduced immune function associated with aging. However, little information is available on the nature of immune...
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Antimicrobial Effect of Coptidis rhizome Extract against Mutans Streptococci and Periodontopathogens

Park SN, Lim YK, Kook JK

The purpose of the study was to investigate the antimicrobial activity of the methanol extract of Coptidis rhizome against the type strains of cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus,...
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Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.

Kim WS, Choi WJ, Lee S, Kim WJ, Lee DC, Sohn UD, Shin HS, Kim W

The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of...
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Antimicrobial Activity of Mulberry Leaf against Mutans Streptococci and Periodontopathogens

Park SN, Lim YK, Cho E, Jo E, Park PS, Kook JK

This study investigated the antimicrobial activity of methanol extract of mulberry leaf against 16 strains of mutans streptococci and four species of periodontopathogens: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and...
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Effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial

Jung GU, Kim JW, Kim SJ, Pang EK

PURPOSE: The purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling and root planing (SRP)...
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Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

Park SN, Kook JK

  • KMID: 1709608
  • Int J Oral Biol.
  • 2013 Dec;38(4):149-154.
In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However,...
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Antimicrobial Activity of Berberine against Oral Bacteria Related to Endodontic Infections

Lee D, Kim MJ, Park SN, Lim YK, Min JB, Hwang HK, Kook JK

  • KMID: 1709607
  • Int J Oral Biol.
  • 2013 Dec;38(4):141-147.
It has been established that berberine has strong antimicrobial effects. Little is known however regarding the antimicrobial activity of berberine against endodontic pathogenic bacteria or its cytotoxicity in human oral...
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Effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from Prevotella intermedia

Cho YJ, Kim SJ

PURPOSE: Nitric oxide (NO) is a short-lived bioactive molecule that is known to play an important role in the pathogenesis of periodontal disease. In the current study, we investigated the...
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Quantitative analysis of periodontal pathogens present in the saliva of geriatric subjects

Shet UK, Oh HK, Kim HJ, Chung HJ, Kim YJ, Kim OS, Choi HR, Kim OJ, Lim HJ, Lee SW

PURPOSE: At present, information regarding periodontal disease in geriatric patients is scarce. The purpose of this study was to quantify the periodontal pathogens present in the saliva of Korean geriatric...
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Periodontopathogen LPSs Regulate MicroRNA Expression in Human Gingival Epithelial Cells

Lee HS, Na HS, Jeong SY, Jeong SH, Park HR, Chung J

  • KMID: 2170740
  • Int J Oral Biol.
  • 2011 Sep;36(3):109-116.
Periodontitis results from the activation of host immune and inflammatory defense responses to subgingival plaque bacteria, most of which are gram-negative rods with lipopolysaccharides (LPSs) in their cell walls. LPSs...
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Strain-specific PCR Primers for the Detection of Prevotella intermedia ATCC 49046

Kim MJ, Min JB, Lim SA, Kook JK

  • KMID: 2170735
  • Int J Oral Biol.
  • 2011 Jun;36(2):79-82.
The aim of this study was to develop Prevotella intermedia ATCC 49046-specific PCR primers designed based on the nucleotide sequence of a DNA probe Pig28. The strain-specificity of the PCR...
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Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells

Kim SJ

PURPOSE: Curcumin is known to exert numerous biological effects including anti-inflammatory activity. In this study, we investigated the effects of curcumin on the production of interleukin-6 (IL-6) by murine macrophage-like...
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Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages

Kim SJ

PURPOSE: In addition to regulating body weight, leptin is also recognized for its role in the regulation of immune function and inflammation. The purpose of this study was to investigate...
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Identification of immunological parameters associated with the alveolar bone level in periodontal patients

Park CS, Lee JY, Kim SJ, Choi JI

PURPOSE: The present study was performed to clarify the relationship between periodontal disease severity and selected immunological parameters consisting of serum IgG titer against periodontopathogenic bacteria, the expression of the...
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Detection of Prevotella intermedia and Prevotella nigrescens using Pn17 and Pn34 DNA Probes

Park CH, Kim PS, Kim HS, Min JB, Hwang HK, Jang HS, Cho KW, Baek DH, Kook JK

  • KMID: 1719928
  • Int J Oral Biol.
  • 2010 Mar;35(1):13-19.
The DNA probes Pn17 and Pn34 were evaluated for their ability to specifically detect clinical strains of P. intermedia and P. nigrescens from a Korean population by dot blot hybridization....
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